Deregulation of the arginine deiminase (arc) operon in penicillin-tolerant mutants of Streptococcus gordonii

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 10, 2000, Pages 2802-2810

  Caldelari, I ^a   Loeliger, B ^a   Langen, H ^a   Glauser, M P ^a   Moreillon, P ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ARGININE DEIMINASE; BACTERIAL DNA; BACTERIAL PROTEIN; BETA LACTAM ANTIBIOTIC; CEFEPIME; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CIPROFLOXACIN; GENTAMICIN; IMIPENEM; ISOPROTEIN; ORNITHINE CARBAMOYLTRANSFERASE; PENICILLIN BINDING PROTEIN; PENICILLIN G; PROTEIN TOL1; RIFAMPICIN; SPARFLOXACIN; STREPTOMYCIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COUNT; BACTERICIDAL ACTIVITY; BACTERIUM CULTURE; BACTERIUM MUTANT; BACTERIUM TRANSFORMATION; CONTROLLED STUDY; DRUG EXPOSURE; DRUG TOLERANCE; GENE CONTROL; GENE FUNCTION; GENE INSERTION; GENE LOCATION; GENETIC RESISTANCE; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PENICILLIN RESISTANCE; POINT MUTATION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE; STREPTOCOCCUS GORDONII;

AMINO ACIDS; BACTERIAL OUTER MEMBRANE PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, BACTERIAL; DNA, BACTERIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROLASES; LUCIFERASE; MEMBRANE PROTEINS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; OPERON; PENICILLIN RESISTANCE; PROTEIN KINASES; STREPTOCOCCUS; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TRANSFORMATION, GENETIC;

EID: 0033802499     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.10.2802-2810.2000     Document Type: Article

References (41)

1. Cross-over study of penicillin pharmacokinetics after intravenous infusions
2. Use of pulsed field gel electrophoresis to compare large DNA-restriction fragments of Listeria monocytogenes strains belonging to serogroups 1/2 3
3. Role of the arginine deiminase system in protecting oral bacteria and an enzymatic basis for acid tolerance
4. Cloning of Streptococcus pneumoniae DNA fragments in Escherichia coli requires vectors protected by strong transcriptional terminators
5. Arginine deiminase system and acid adaptation of oral streptococci
6. Penicillin tolerance in Enterococcus hirae ATCC 9790
7. Inhibition of human peripheral blood mononuclear cell proliferation by Streptococcus pyogenes cell extracts is associated with arginine deiminase activity
8. Origin and molecular epidemiology of penicillin binding-protein-mediated resistance to beta-lactam antibiotics
9. Importance of genotypic and phenotypic tolerance in the treatment of experimental endocarditis due to Streptococcus gordonii
10. Efficacy of levofloxacin in the treatment of experimental endocarditis caused by viridans group streptococci
11. Opposing roles of the Staphylococcus aureus virulence regulators, Agr and Sar, in Triton X-100- and penicillininduced autolysis
12. Serine beta-lactamases and penicillin-binding proteins
13. A novel, 'hidden' penicillin-induced death of staphylococci at high drug concentration, occurring earlier than murosome-mediated killing processes
14. Penicillin-resistant and penicillin-tolerant mutants of group A streptococci
15. Role of porins in outer membrane permeability
16. Antibiotic tolerance among clinical isolates of bacteria
17. Catabolite repression in Bacillus subtilis: A global regulatory mechanism for the gram-positive bacteria?
18. Analysis of a cis-active sequence mediating catabolite repression in gram-positive bacteria
19. Streptococcal antitumor protein: Expression in Escherichia coli cells and properties of the recombinant protein
20. Association of penicillin tolerance with failure to eradicate group A streptococci from patients with pharyngitis
21. Two-dimensional map of the proteome of Haemophilus influenzae
22. Penicillin tolerance in multiply drugresistant natural isolates of Streptococcus pneumoniae
23. The arc-ABDC gene cluster, encoding the arginine deiminase pathway of Bacillus licheniformis, and its activation by the arginine repressor argR
24. Rapid preparation of bacterial DNA for pulsed-field gel electrophoresis
25. Absence of autolytic activity (peptidoglycan nicking) in penicillin-induced nonlytic death in a group A streptococcus
26. Two bactericidal targets for penicillin in pneumococci: Autolysis-dependent and autolysis-independent killing mechanisms
27. Penicillin resistance and defective lysis in clinical isolates of pneumococci: Evidence for two kinds of antibiotic pressure operating in the clinical environment
28. Prevention of drug access to bacterial targets: Permeability barriers and active efflux
29. Penicillin tolerance genes of Streptococcus pneumoniae: The ABC-type manganese permease complex Psa
30. Identification of a Streptococcus pneumoniae gene locus encoding proteins of an ABC phosphate transporter and a two-component regulatory system
31. Emergence of vancomycin tolerance in Streptococcus pneumoniae
32. Collagenase gene (colA) is located in the 3'-flanking region of the perfringolysin O (pfoA) locus in Clostridium perfringens
33. Method and parameters for genetic transformation of Streptococcus sanguis Challis
34. A new type of penicillin resistance of Staphylococcus aureus
35. Suppression of penicillin-induced lysis of Staphylococcus aureus by cibacron blue 3G-A
36. Localized perforation of the cell wall by a major autolysin: Atl gene products and the onset of penicillin-induced lysis of Staphylococcus aureus
37. Multiple antibiotic resistance in a bacterium with suppressed autolytic system
38. Phenotypic tolerance: The search for beta-lactam antibiotics that kill nongrowing bacteria
39. Antimicrobial susceptibility tests: Dilution and disk diffusion methods
40. Structural and functional analysis of the gene cluster encoding the enzymes of the arginine deiminase pathway of Lactobacillus sake