메뉴 건너뛰기




Volumn 255, Issue 2, 1998, Pages 391-399

Expression, structure and chromosomal localization of the human cGMP-binding cGMP-specific phosphodiesterase PDE5A gene

Author keywords

Genome; Guanosine 3',5' phosphate; Human cDNA; Phosphodiesterase

Indexed keywords

CYCLIC GMP PHOSPHODIESTERASE; MESSENGER RNA;

EID: 7344243173     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2550391.x     Document Type: Article
Times cited : (113)

References (40)
  • 1
    • 0026844552 scopus 로고
    • Regulation and function of cyclic nucleotides
    • Bentley, J. K. & Beavo, J. A. (1992) Regulation and function of cyclic nucleotides, Curr. Opin. Cell Biol. 2, 233-240.
    • (1992) Curr. Opin. Cell Biol. , vol.2 , pp. 233-240
    • Bentley, J.K.1    Beavo, J.A.2
  • 3
    • 0025215525 scopus 로고
    • Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors
    • Beavo, J. A. & Reifsnyder, D. H. (1990) Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors, Trends. Pharmacol. Sci. 11, 150-155.
    • (1990) Trends. Pharmacol. Sci. , vol.11 , pp. 150-155
    • Beavo, J.A.1    Reifsnyder, D.H.2
  • 4
    • 0018595710 scopus 로고
    • Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments
    • Bachr, W., Devlin, M. J. & Applebury, M. L. (1979) Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments, J. Biol. Chem. 254, 11669-11677.
    • (1979) J. Biol. Chem. , vol.254 , pp. 11669-11677
    • Bachr, W.1    Devlin, M.J.2    Applebury, M.L.3
  • 5
    • 0023918102 scopus 로고
    • Characterization of a bovine cone photoreceptor phosphodiesterase purified by cyclic GMP-sepharose chromatograph
    • Gillespie, P. G. & Beavo, J. A. (1988) Characterization of a bovine cone photoreceptor phosphodiesterase purified by cyclic GMP-sepharose chromatograph, J. Biol. Chem. 263, 8133-8141.
    • (1988) J. Biol. Chem. , vol.263 , pp. 8133-8141
    • Gillespie, P.G.1    Beavo, J.A.2
  • 6
    • 0019136606 scopus 로고
    • Cyclic GMP-specific, high affinity, noncatalytic binding sites on light-activated phosphodiesterase
    • Yamazaki, A., Sen, I., Bitensky, M. W., Casnellie, J. E. & Greengard, P. (1980) Cyclic GMP-specific, high affinity, noncatalytic binding sites on light-activated phosphodiesterase. J. Biol. Chem. 255, 11619-11624.
    • (1980) J. Biol. Chem. , vol.255 , pp. 11619-11624
    • Yamazaki, A.1    Sen, I.2    Bitensky, M.W.3    Casnellie, J.E.4    Greengard, P.5
  • 7
    • 0019205204 scopus 로고
    • Characteristics of a new binding protein distinct from the kinase for guanosine 3′:5′-monophosphate in rat platelets
    • Coquil, J.-F., Franks, D. J, Wells, J. N., Dupuis, M. & Hamet, P. (1980) Characteristics of a new binding protein distinct from the kinase for guanosine 3′:5′-monophosphate in rat platelets, Biochim. Biophys. Acta 631, 148-165.
    • (1980) Biochim. Biophys. Acta , vol.631 , pp. 148-165
    • Coquil, J.-F.1    Franks, D.J.2    Wells, J.N.3    Dupuis, M.4    Hamet, P.5
  • 8
    • 0021996920 scopus 로고
    • Occurrence of the methylisobutylxanthine-stimulated cyclic GMP binding protein in various rat tissues
    • Coquil, J.-F., Brunelle, G. & Guédon. J. (1985) Occurrence of the methylisobutylxanthine-stimulated cyclic GMP binding protein in various rat tissues, Biochem. Biophys. Res. Commun. 127, 226-231.
    • (1985) Biochem. Biophys. Res. Commun. , vol.127 , pp. 226-231
    • Coquil, J.-F.1    Brunelle, G.2    Guédon, J.3
  • 9
    • 0023723086 scopus 로고
    • Purification of cGMP-binding protein phosphodiesterase from rat lung
    • Francis, S. H. & Corbin, J. D. (1988) Purification of cGMP-binding protein phosphodiesterase from rat lung, Methods Enzymol. 159, 722-799.
    • (1988) Methods Enzymol. , vol.159 , pp. 722-799
    • Francis, S.H.1    Corbin, J.D.2
  • 11
    • 0025041146 scopus 로고
    • Characterization of a purified bovine lung cGMP-binding cGMP phosphodiesterase
    • Thomas, M. K., Francis, S. H. & Corbin, J. D. (1990) Characterization of a purified bovine lung cGMP-binding cGMP phosphodiesterase, J. Biol. Chem. 265, 14971-14978.
    • (1990) J. Biol. Chem. , vol.265 , pp. 14971-14978
    • Thomas, M.K.1    Francis, S.H.2    Corbin, J.D.3
  • 12
    • 0025092063 scopus 로고
    • Characterization and selective inhibition of cyclic nucleotide phosphodiesterase isozymes in canine tracheal smooth muscle
    • Torphy, T. J. & Cieslinski, L. B. (1990) Characterization and selective inhibition of cyclic nucleotide phosphodiesterase isozymes in canine tracheal smooth muscle, Mol. Pharmacol. 37, 206-214.
    • (1990) Mol. Pharmacol. , vol.37 , pp. 206-214
    • Torphy, T.J.1    Cieslinski, L.B.2
  • 13
    • 0021874540 scopus 로고
    • Evidence that cyclic guanosine monophosphate (cGMP) mediates endothelium-dependent relaxation
    • Griffith, T. M., Edwards, D. H., Lewis, M. J. & Henderson, A. H. (1985) Evidence that cyclic guanosine monophosphate (cGMP) mediates endothelium-dependent relaxation, Eur. J. Pharmacol. 112, 195-202.
    • (1985) Eur. J. Pharmacol. , vol.112 , pp. 195-202
    • Griffith, T.M.1    Edwards, D.H.2    Lewis, M.J.3    Henderson, A.H.4
  • 14
    • 0015335885 scopus 로고
    • Hypoxic pulmonary hypertension its modification by dipyridamole
    • Rosenkrantz, J. G., Lynch, F. P. & Vogel, J. H. K. (1972) Hypoxic pulmonary hypertension its modification by dipyridamole, J. Surg. Res. 12, 330-333.
    • (1972) J. Surg. Res. , vol.12 , pp. 330-333
    • Rosenkrantz, J.G.1    Lynch, F.P.2    Vogel, J.H.K.3
  • 15
    • 0027406998 scopus 로고
    • M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs
    • Braner, D. A. V., Fineman, J. R., Chang, R. & Soifer, S. J. (1993) M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs. Am. J. Physiol. 264, H252-H258.
    • (1993) Am. J. Physiol. , vol.264
    • Braner, D.A.V.1    Fineman, J.R.2    Chang, R.3    Soifer, S.J.4
  • 16
    • 0030070656 scopus 로고    scopus 로고
    • Inhibition of cyclic 3′-5′-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats
    • Cohen, A. H., Hanson, K., Morris, K., Fouty, B., McMurtry, I. F., Clarke, W. & Rodman, D. M. (1996) Inhibition of cyclic 3′-5′-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats, J. Clin. Invest. 97, 172-179.
    • (1996) J. Clin. Invest. , vol.97 , pp. 172-179
    • Cohen, A.H.1    Hanson, K.2    Morris, K.3    Fouty, B.4    McMurtry, I.F.5    Clarke, W.6    Rodman, D.M.7
  • 17
    • 0027167474 scopus 로고
    • Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed
    • McMahon, T. J., Ignarro, L. J. & Kadowitz, P. J. (1993) Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed, J. Appl. Physiol. 74, 1704-1711.
    • (1993) J. Appl. Physiol. , vol.74 , pp. 1704-1711
    • McMahon, T.J.1    Ignarro, L.J.2    Kadowitz, P.J.3
  • 18
    • 0028131402 scopus 로고
    • Effects of a novel, selective and potent phosphodiesterase type V inhibitor, E4021, on myocardial ischemia in guinea pigs
    • Kodama, K., Adachi, H., Mori, N. & Saito, I. (1994) Effects of a novel, selective and potent phosphodiesterase type V inhibitor, E4021, on myocardial ischemia in guinea pigs, Eur. J. Pharmacol. 263, 93-99.
    • (1994) Eur. J. Pharmacol. , vol.263 , pp. 93-99
    • Kodama, K.1    Adachi, H.2    Mori, N.3    Saito, I.4
  • 19
    • 0027217383 scopus 로고
    • Zaprinast, cicletanine, and verapamil attenuate overdrive pacing-induced myocardial ischemia in conscious rabbits
    • Szilvassy, Z., Jakab, I., Ferdinandy, P., Koltai, M., Lonovics, J., Tarrade, T. & Braquet, P. G. (1993) Zaprinast, cicletanine, and verapamil attenuate overdrive pacing-induced myocardial ischemia in conscious rabbits, Life Sci. 53, 13-18.
    • (1993) Life Sci. , vol.53 , pp. 13-18
    • Szilvassy, Z.1    Jakab, I.2    Ferdinandy, P.3    Koltai, M.4    Lonovics, J.5    Tarrade, T.6    Braquet, P.G.7
  • 20
    • 0030438222 scopus 로고    scopus 로고
    • Sildenafil, a novel effective therapy for male erectile dysfunction
    • Boolell, M., Gepi-Attee, S., Gingell, J. C. & Allen, M. J. (1996) Sildenafil, a novel effective therapy for male erectile dysfunction, Br. J. Urol. 78, 257-261.
    • (1996) Br. J. Urol. , vol.78 , pp. 257-261
    • Boolell, M.1    Gepi-Attee, S.2    Gingell, J.C.3    Allen, M.J.4
  • 22
    • 0030725663 scopus 로고    scopus 로고
    • Expression of rat cGMP-binding, cGMP-specific phosphodiesterase mRNA in Purkinje cell layers during postnatal neuronal development
    • Kotera, J., Yanaka, N., Fujishige, K., Imai, Y., Akatsuka, H., Ishizuka, T., Kawashima, K. & Omori, K. (1997) Expression of rat cGMP-binding, cGMP-specific phosphodiesterase mRNA in Purkinje cell layers during postnatal neuronal development, Eur. J. Biochem. 249, 434-442.
    • (1997) Eur. J. Biochem. , vol.249 , pp. 434-442
    • Kotera, J.1    Yanaka, N.2    Fujishige, K.3    Imai, Y.4    Akatsuka, H.5    Ishizuka, T.6    Kawashima, K.7    Omori, K.8
  • 24
    • 0016684404 scopus 로고
    • Cyclic nucleotide phosphodiesterase activates of pig coronary arteries
    • Wells, J. N., Baird, C. E., Wu, Y. J. & Hardman, J. G. (1975) Cyclic nucleotide phosphodiesterase activates of pig coronary arteries, Biochim. Biophys. Acta 384, 430-442.
    • (1975) Biochim. Biophys. Acta , vol.384 , pp. 430-442
    • Wells, J.N.1    Baird, C.E.2    Wu, Y.J.3    Hardman, J.G.4
  • 25
    • 0028919274 scopus 로고
    • Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C tochromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23
    • Okumura, K., Nogami, M., Taguchi, H., Dean, F. B., Chen. M., Pan, Z.-Q., Hurwitz, J., Shiratori, A., Murakami, Y., Ozawa, K. & Eki, T. (1995) Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C tochromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23, Genomics 25, 274-278.
    • (1995) Genomics , vol.25 , pp. 274-278
    • Okumura, K.1    Nogami, M.2    Taguchi, H.3    Dean, F.B.4    Chen, M.5    Pan, Z.-Q.6    Hurwitz, J.7    Shiratori, A.8    Murakami, Y.9    Ozawa, K.10    Eki, T.11
  • 26
    • 0025200279 scopus 로고
    • R-banding and nonisotopic in situ hybridization: Precise localization of the human type II collagen gene (COL2A1)
    • Takahashi, E., Hori, T., O'Connell, P., Leppert, M. & White, R. (1990) R-banding and nonisotopic in situ hybridization: precise localization of the human type II collagen gene (COL2A1), Hum. Genet. 86, 14-16.
    • (1990) Hum. Genet. , vol.86 , pp. 14-16
    • Takahashi, E.1    Hori, T.2    O'Connell, P.3    Leppert, M.4    White, R.5
  • 27
    • 0023692635 scopus 로고
    • Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries
    • Lichter, P., Cremer, T., Borden, J., Manuelidis, L. & Ward, D. C. (1988) Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries, Hum. Genet. 80, 224-234.
    • (1988) Hum. Genet. , vol.80 , pp. 224-234
    • Lichter, P.1    Cremer, T.2    Borden, J.3    Manuelidis, L.4    Ward, D.C.5
  • 28
    • 0025041146 scopus 로고
    • Substrate- and kinase-directed regulation of phosphorylation of a cGMP-binding phosphodiesterase by cGMP
    • Thomas, M. K., Francis, S. H. & Corbin, J. D. (1990) Substrate- and kinase-directed regulation of phosphorylation of a cGMP-binding phosphodiesterase by cGMP, J. Biol. Chem. 265, 14964-14970.
    • (1990) J. Biol. Chem. , vol.265 , pp. 14964-14970
    • Thomas, M.K.1    Francis, S.H.2    Corbin, J.D.3
  • 29
    • 0017089669 scopus 로고
    • 3′ Non-coding region sequences in eukaryotic messenger RNA
    • Proudfoot, N. J. & Brownlee, G. G. (1976) 3′ Non-coding region sequences in eukaryotic messenger RNA, Nature 263, 211-214.
    • (1976) Nature , vol.263 , pp. 211-214
    • Proudfoot, N.J.1    Brownlee, G.G.2
  • 30
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw, G. & Kamen, R. (1986) A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation, Cell 46, 659-667.
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 31
    • 0029084745 scopus 로고
    • Isoenzymes of cyclic nucleotide phosphodiesterase in the human aorta: Characterization and the effects of E4021
    • Miyahara, M., Ito, M., Itoh, H., Shiraishi, T., Isaka, N., Konishi, T. & Nakano, T. (1995) Isoenzymes of cyclic nucleotide phosphodiesterase in the human aorta: characterization and the effects of E4021, Eur. J. Pharmacol. 284, 25-33.
    • (1995) Eur. J. Pharmacol. , vol.284 , pp. 25-33
    • Miyahara, M.1    Ito, M.2    Itoh, H.3    Shiraishi, T.4    Isaka, N.5    Konishi, T.6    Nakano, T.7
  • 32
    • 0025321246 scopus 로고
    • Splice junctions, branch point sites, and exons: Sequence statistics, identification, and applications to genome project
    • Senapathy, P., Shapiro, M. B. & Harris, N. L. (1990) Splice junctions, branch point sites, and exons: sequence statistics, identification, and applications to genome project, Methods Enzymol. 183, 252-278.
    • (1990) Methods Enzymol. , vol.183 , pp. 252-278
    • Senapathy, P.1    Shapiro, M.B.2    Harris, N.L.3
  • 33
    • 0025992248 scopus 로고
    • Genomic organization and complete sequence of the human gene encoding the b-subunit of the cGMP phosphodiesterase and its localization to 4p16.3
    • Weber, B., Riess, O., Hutchinson, G., Collins, C., Lin, B.-Y., Kowbel, D., Andrew, S., Schappert, K. & Hayden, M. R. (1991) Genomic organization and complete sequence of the human gene encoding the b-subunit of the cGMP phosphodiesterase and its localization to 4p16.3, Nucleic Acids Res. 19, 6263-6268.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 6263-6268
    • Weber, B.1    Riess, O.2    Hutchinson, G.3    Collins, C.4    Lin, B.-Y.5    Kowbel, D.6    Andrew, S.7    Schappert, K.8    Hayden, M.R.9
  • 34
    • 0029038905 scopus 로고
    • Drosophila midgut morphogenesis requires the function of the segmentation gene odd-paired
    • Cimbora, D. M. & Sakonju, S. (1995) Drosophila midgut morphogenesis requires the function of the segmentation gene odd-paired. Dev. Biol. 169, 580-595.
    • (1995) Dev. Biol. , vol.169 , pp. 580-595
    • Cimbora, D.M.1    Sakonju, S.2
  • 36
    • 0030047931 scopus 로고    scopus 로고
    • Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts. Characterization of a novel tissue-specific isoform, RNPDE4A8
    • Bolger, G. B., McPhee, I. & Houslay, M. D. (1996) Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts. Characterization of a novel tissue-specific isoform, RNPDE4A8, J. Biol. Chem. 271, 1065-1071.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1065-1071
    • Bolger, G.B.1    McPhee, I.2    Houslay, M.D.3
  • 37
    • 0027509357 scopus 로고
    • Molecular cloning of a cDNA encoding the "61-kDa" calmodulin-stimulated cyclic nucleotide phosphodiesterase. Tissue-specific expression of structurally related isoforms
    • Sonnenburg, W. K., Seger, D. & Beavo, J. A. (1993) Molecular cloning of a cDNA encoding the "61-kDa" calmodulin-stimulated cyclic nucleotide phosphodiesterase. Tissue-specific expression of structurally related isoforms, J. Biol. Chem. 268, 645-652.
    • (1993) J. Biol. Chem. , vol.268 , pp. 645-652
    • Sonnenburg, W.K.1    Seger, D.2    Beavo, J.A.3
  • 39
    • 0028822195 scopus 로고
    • An endogenous protectant effect of cardiac cyclic GMP against reperfusion-induced ventricular fibrillation in the rat heart
    • Pabla, R., Bland-Ward, P., Moore, P. K. & Curtis, M. J. (1995) An endogenous protectant effect of cardiac cyclic GMP against reperfusion-induced ventricular fibrillation in the rat heart, Br. J. Pharmacol. 116, 2923-2930.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 2923-2930
    • Pabla, R.1    Bland-Ward, P.2    Moore, P.K.3    Curtis, M.J.4
  • 40
    • 0028946977 scopus 로고
    • 2+ channel activity by human natriuretic peptide in rabbit heart cells
    • 2+ channel activity by human natriuretic peptide in rabbit heart cells, Br. J. Pharmacol. 114, 1076-1082.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 1076-1082
    • Tohse, N.1    Nakaya, H.2    Takeda, Y.3    Kanno, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.