Antigen-specific production of RANTES, Macrophage Inflammatory Protein (MIP)-1α, and MIP-1β in vitro is a correlate of reduced human immunodeficiency virus burden in vivo

Journal of Infectious Diseases

Volumn 182, Issue 4, 2000, Pages 1247-1250

  Ferbas, John ^a,b   Giorgi, Janis V ^a   Amini, Shamim ^a   Grovit Ferbas, Kathie ^a,b   Wiley, Dorothy J ^a   Detels, Roger ^a   Plaeger, Susan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES;

ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CYTOKINE PRODUCTION; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL TIME; VIRUS LOAD;

CD4 LYMPHOCYTE COUNT; CD8-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; COMPARATIVE STUDY; ENZYME-LINKED IMMUNOSORBENT ASSAY; HETEROZYGOTE; HIV INFECTIONS; HOMOZYGOTE; HUMAN; MACROPHAGE INFLAMMATORY PROTEIN-1; PROTEIN ISOFORMS; RANTES; RNA, VIRAL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SURVIVORS; VIRAL LOAD;

EID: 0033795903     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315849     Document Type: Article

References (15)

1. +, T-cell clones correlates with the clinical state of human immunodeficiency virus type 1 (HIV-1)-infected individuals and may be responsible for blocking infection with non-syncytium-inducing HIV-1 in vitro
2. Production of beta-chemokines in human immunodeficiency virus (HIV) infection: Evidence that high levels of macrophage inflammatory protein-1β are associated with a decreased risk of HIV disease progression
3. Influence of host genes on HIV-1 disease progression
4. Do β-chemokines have clinical relevance in HIV infection?
5. + lymphocyte activity
6. Quantitation of CD38 expression using QuantiBRITE beads
7. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro
8. + T-lymphocyte activation in HIV-1 disease reflects an aspect of pathogenesis distinct from viral burden and immunodeficiency
9. Evolution and plasticity of CTL responses against HIV
10. + lymphocytes from exposed-uninfected individuals: Association with low expression of CCR5 and high production of β-chemokines
11. β-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans
12. C-C chemokines released by lipopolysaccharide (LPS)-stimulated human macrophages suppress HIV-1 infection in both macrophages and T cells
13. + patients produce C-C chemokines and inhibit HIV-1 infection
14. Cytokine immunotrapping: An assay to study the kinetics of production and consumption or degradation of human interferon-γ
15. The HIV coreceptors CXCR4 and CCR5 are difterentially expressed and regulated on human T lymphocytes