Gelatinase activities in wounds of healing-impaired mice versus wounds of non-healing-impaired mice

Journal of Burn Care and Rehabilitation

Volumn 21, Issue 5, 2000, Pages 395-402

  Neely, A N ^a   Clendening, C E ^a   Gardner, J ^a   Greenhalgh, D G ^a  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE; GELATINASE A; GELATINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; FULL THICKNESS SKIN GRAFT; MOUSE; NONHUMAN; PROTEIN DEGRADATION; SCAR FORMATION; WOUND CARE; WOUND CLOSURE; WOUND HEALING; ZYMOGRAPHY;

EID: 0033795456     PISSN: 02738481     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004630-200021050-00001     Document Type: Article

References (34)

1. Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
2. Diabetes-obesity syndromes in mice
3. PDGF and FGF stimulates wound healing in the genetically diabetic mouse
4. Apoptosis down-regulates inflammation under the advancing epithelial wound edge: Delayed patterns in diabetes and improvement with topical growth factors
5. Apoptosis is increased in a model of diabetes-impaired wound healing in genetically diabetic mice
6. A wound healing model using healing-impaired diabetic mice
7. Synergistic actions of platelet-derived growth factor and the insulin-like growth factors in vivo
8. Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse
9. Assessment of full-thickness wounds in the genetically diabetic mouse for suitability as a wound healing model
10. Cutaneous wound repair
11. Proteinases and matrix degradation
12. Purification and characterisation of human 72-kDA gelatinase (type IV collagenase): Use of immunolocalization to demonstrate the non-coordinate regulation of the 72-kDA and 92-kDA gelatinases by human fibroblasts
13. The matrix-degrading metalloproteinases
14. Gelatinase activity during wound healing
15. Quantification of matrix metalloproteinases in tissue samples
16. Comparison of wound healing among excisional, laser-created, and standard thermal burns in porcine wounds of equal depth
17. Matrix metalloproteinases (MMPs) and their physiological inhibitors (TIMPs) are differentially expressed during excisional skin wound repair
18. Transforming growth factor-β and insulin-like growth factor-1 in relation to diabetes-induced impairment of wound healing
19. Metalloproteinase activation cascade after burn injury: A longitudinal analysis of the human wound environment
20. Proteolytic activity in human burn wounds
21. Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9
22. Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids
23. Matrix metalloproteinases, gelatinase and collagenase in chronic leg ulcers
24. Interactions of cytokines, growth factors, and proteases in acute and chronic wounds
25. Bacterial collagenases and collagen-degrading enzymes and their potential role in human disease
26. Noncytotoxic combinations of topical antimicrobial agents for use with cultured skin substitutes
27. Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines
28. Activity of type IV coliagenases in benign and malignant breast disease
29. Gelatinase activity in keloids and hypertrophic scars
30. Detergent-activation of latent collagenase and resolution of its component molecules
31. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing SDS and copolymerized substrates
32. Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodeling cornea
33. Demonstration of 72-kDa and 92-kDa forms of type IV collagenase in human skin: Variable expression in various blistering diseases, induction during re-epithelialization, and decrease by topical glucocorticoids
34. Role and regulation of the matrix metalloproteinase, gelatinase B, in normal and repairing skin