Characterization of cleaved plasma protein S with a monoclonal antibody-based assay

Thrombosis and Haemostasis

Volumn 84, Issue 4, 2000, Pages 604-610

  Morboeuf, O ^a   Borgel, D ^a   Gaussem, P ^a   Vincenot, A ^a   Pittet, J L ^a   Aiach, M ^a   Gandrille, S ^a  

^a INSERM   (France)

Author keywords

Cleaved plasma protein S; Epitope mapping; Monoclonal antibody; Thrombin sensitive region

Indexed keywords

ANTICOAGULANT AGENT; ARGININE DERIVATIVE; BLOOD CLOTTING FACTOR 10A; MONOCLONAL ANTIBODY; PLASMA PROTEIN; PROTEIN S; PROTHROMBIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BLOOD CLOTTING DISORDER; CLINICAL ARTICLE; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; HEMOPHILIA; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; SERUM CHARACTERISTICS;

EID: 0033790726     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1614075     Document Type: Article

References (22)

1. Characterization of protein S, a γ-carboxyglutamic acid containing protein from bovine and human plasma
2. A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor) and protein S
3. Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C
4. Inactivation of factor VIII by activated protein C and protein S
5. Familial protein S deficiency is associated with recurrent thrombosis
6. High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein
7. Inhibition of protein Ca cofactor function of human and bovine protein S by C4-binding protein
8. Purification of human vitamin-K dependent protein S and its limited proteolysis by thrombin
9. Regulation of vitamin K-dependent protein S, inactivation by thrombin
10. Regulation of activated protein C by thrombin-modified protein S
11. The effect of N-linked glycosylation on molecular weight, thrombin cleavage, and functional activity of human protein S
12. Control of thrombin mediated cleavage of protein S
13. Human protein S cleavage and inactivation by coagulation factor Xa
14. Protein S degradation in vitro by neutrophil elastase
15. The factor V gene A4070G mutation and the risk of venous thrombosis
16. Detection of factor X activation in humans
17. Factor IXa-factor VIIIa-cell surface complex does not contribute to the basal activation of the coagulation mechanism in vivo
18. Acquired deficiencies of protein S. Protein S activity during oral anticoagulation, in liver disease, and in disseminated intravascular coagulation
19. Evaluation of the relationship between protein S and C4b-binding protein isoforms in hereditary protein S deficiency demonstrating type I and type III deficiencies to be phenotypic variants of the same genetic disease
20. Activation and complexation of protein C and cleavage and decrease of protein S in plasma of patients with intravascular coagulation
21. Monitoring 'mini-intensity' anticoagulation with warfarin: Comparison of the prothrombin time using a sensitive thromboplastin with prothrombin fragment F1+2 levels