Parathyroid hormone-related protein regulates extracellular matrix gene expression in cementoblasts and inhibits cementoblast-mediated mineralization in vitro

Journal of Bone and Mineral Research

Volumn 15, Issue 11, 2000, Pages 2140-2153

  Ouyang, Hongjiao ^a   McCauley, Laurie K ^a   Berry, Janice E ^a   Saygin, N Esra ^a   Tokiyasu, Yoshihiko ^a,b   Somerman, Martha J ^a,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Biomineralization; Bone sialoprotein; Cementoblasts; Parathyroid hormone related protein; Parathyroid hormone parathyroid hormone related protein receptor

Indexed keywords

PARATHYROID HORMONE RELATED PROTEIN; SIALOPROTEIN;

ANIMAL CELL; ARTICLE; BONE GROWTH; CELL IMMORTALIZATION; CEMENTUM; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENE INDUCTION; IN VITRO STUDY; MINERALIZATION; MOLECULAR CLONING; NONHUMAN; ONCOGENE C FOS; OSTEOBLAST; PROTEIN SYNTHESIS REGULATION; SPINDLE CELL; TOOTH ERUPTION;

ANIMAL; CELL TRANSPLANTATION; CELLS, CULTURED; CLONE CELLS; COLLAGEN; CYCLIC AMP; DENTAL CEMENTUM; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENES, FOS; MICE; MICE, INBRED STRAINS; MICE, SCID; MINERALS; OSTEOCALCIN; PERIODONTAL LIGAMENT; PROTEINS; RECEPTORS, PARATHYROID HORMONE; SIALOGLYCOPROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0033787957     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2000.15.11.2140     Document Type: Article

References (60)

1. Dental cementum: The dynamic tissue covering of the root
2. Immunocytochemical investigation of the rat cementoblast phenotype
3. Developmental appearance and distribution of bone sialoprotein and osteopontin in human and rat cementum
4. Osteopontin and bone sialoprotein expression in regenerating rat periodontal ligament and alveolar bone
5. Extracellular matrix in tooth cementum and mantle dentin: Localization of osteopontin and other noncollagenous proteins, plasma proteins, and glycoconjugates by electron microscopy
6. Mechanism of fibroblast attachment to bone extracellular matrix: Role of a 44 kilodalton bone phosphoprotein
7. Expression of bone associated markers by tooth root lining cells, in situ and in vitro
8. Site-specific expression of mRNAs for osteonectin, osteocalcin, and osteopontin revealed by in situ hybridization in rat periodontal ligament during physiological tooth movement
9. Expression of attachment proteins during cementogenesis
10. A new look at the etiology and pathogenesis of early-onset periodontitis. Cementopathia revisited
11. The new concept of periodontoclasia
12. Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation
13. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene
14. Expression of parathyroid hormone-related peptide and its receptor messenger ribonucleic acids during fetal development of rats
15. PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth
16. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
17. The expression of the gene coding for parathyroid hormone-related protein (PTHrP) during tooth development in the rat
18. An immunohistochemical investigation of the expression of parathyroid hormone receptors in rat cementoblasts
19. Response of immortalized murine cementoblasts/periodontal ligament cells to parathyroid hormone and parathyroid hormone-related protein in vitro
20. Parathyroid hormone-related protein is required for tooth eruption
21. Normal human cementum-derived cells: Isolation, clonal expansion, and in vitro and in vivo characterization
22. Isolation of human tumor cells that produce cementum proteins in culture
23. Immortalized cementoblasts and periodontal ligament cells in culture
24. Employing a transgenic animal model to obtain cementoblasts, in vitro
25. Bone sialoprotein is localized to the root surface during cementogenesis
26. Osteoblastic cell lines derived from a transgenic mouse containing the osteocalcin promoter driving SV40 T-antigen
27. 1 regulates steady-state PTH/PTHrP receptor mRNA levels and PTHrP binding in ROS 17/2.8 osteosarcoma cells
28. Murine bone sialoprotein (BSP): cDNA cloning, mRNA expression, and genetic mapping
29. The bone morphogenetic protein family and osteogenesis
30. Matrix sialoprotein of developing bone
31. cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)
32. A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide
33. Protooncogene c-fos is transcriptionally regulated by parathyroid hormone (PTH) and PTH-related protein in a cyclic adenosine monophosphate-dependent manner in osteoblastic cells
34. Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle
35. Ribosomal DNA of fly Sciara coprophila has a very small and homogeneous repeat unit
36. PTH/PTHrP receptor is temporally regulated during osteoblast differentiation and is associated with collagen synthesis
37. Parathyroid hormone-related protein binding to human T-cell lymphotropic virus type I-infected lymphocytes
38. Effects of differentiation and transforming growth factor beta 1 on PTH/PTHrP receptor mRNA levels in MC3T3-E1 cells
39. Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells
40. Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
41. Evolution of periodontal regeneration: From the roots' point of view
42. Bone formation in vivo: Comparison of osteogenesis by transplanted mouse and human marrow stromal fibroblasts
43. Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium
44. Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: In situ localization of its receptor and c-fos messenger ribonucleic acids
45. Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: A model for intercellular communication in bone
46. Parathyroid hormone induces c-fos promoter activity in osteoblastic cells through phosphorylated cAMP response element (CRE)-binding protein binding to the major CRE
47. Models for the study of cementogenesis
48. Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
49. Cementum-forming cells are phenotypically distinct from bone-forming cells
50. Demonstration of receptors for parathyroid hormone on cultured rabbit costal chondrocytes
51. Effects of various growth and differentiation factors on expression of parathyroid hormone receptors on rabbit costal chondrocytes in culture
52. 3',5'- Cyclic adenosine monophosphate activation in osteoblastic cells: Effects on parathyroid hormone-1 receptors and osteoblastic differentiation in vitro
53. Comparative effects of parathyroid hormone on osteoblasts and cementoblasts
54. Dental aspects of hyperparathyroidism
55. Role of two mineral-associated adhesion molecules, osteopontin and bone sialoprotein, during cementogenesis
56. Modulation of crystal formation by bone phosphoproteins: Structural specificity of the osteopontin-mediated inhibition of hydroxyapatite formation
57. Signal transduction pathways mediating parathyroid hormone stimulation of bone sialoprotein gene expression in osteoblasts
58. Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells
59. Anabolic or catabolic responses of MC3T3-E1 osteoblastic cells to parathyroid hormone depend on time and duration of treatment
60. Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages