메뉴 건너뛰기




Volumn 69, Issue 5, 2000, Pages 574-578

Psychological impact of genetic testing for Huntington's disease: An update of the literature

Author keywords

Genetic testing; Huntington's disease; Psychological adjustment

Indexed keywords

ADJUSTMENT; DISTRESS SYNDROME; GENE MUTATION; GENETIC ANALYSIS; GENETIC COUNSELING; GENETIC LINKAGE; HUMAN; HUNTINGTON CHOREA; PREDICTION; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; REVIEW;

EID: 0033785340     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.69.5.574     Document Type: Review
Times cited : (172)

References (38)
  • 2
    • 0021028244 scopus 로고
    • A polymorphic DNA marker genetically linked to Huntington's disease
    • Gusella JF, Wexler NS, Conneally PM, et al. A polymorphic DNA marker genetically linked to Huntington's disease. Nature 1983;306:234-9.
    • (1983) Nature , vol.306 , pp. 234-239
    • Gusella, J.F.1    Wexler, N.S.2    Conneally, P.M.3
  • 3
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable in Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable in Huntington's disease chromosomes. Cell 1993;72:971-83.
    • (1993) Cell , vol.72 , pp. 971-983
  • 4
    • 0028023974 scopus 로고
    • Proceed with care: Direct predictive testing for Huntington's disease
    • Benjamin C, Adam S, Wiggins S, et al. Proceed with care: direct predictive testing for Huntington's disease. Am J Med Genet 1994;55:606-7.
    • (1994) Am J Med Genet , vol.55 , pp. 606-607
    • Benjamin, C.1    Adam, S.2    Wiggins, S.3
  • 5
    • 0022548975 scopus 로고
    • Suicide and attempted suicide in Huntington's disease: Implications for preclinical testing of persons at risk
    • Farrer LA. Suicide and attempted suicide in Huntington's disease: implications for preclinical testing of persons at risk. Am J Med Genet 1986;24:305-11.
    • (1986) Am J Med Genet , vol.24 , pp. 305-311
    • Farrer, L.A.1
  • 6
    • 0022859160 scopus 로고
    • Attitudes toward presymptomatic testing in Huntington's disease
    • Mastromauro C, Myers RH, Berkman B. Attitudes toward presymptomatic testing in Huntington's disease. Am J Med Genet 1987;26:271-82.
    • (1987) Am J Med Genet , vol.26 , pp. 271-282
    • Mastromauro, C.1    Myers, R.H.2    Berkman, B.3
  • 7
    • 0021171868 scopus 로고
    • Potential impact of a predictive test on the gene frequency of Huntington's disease
    • Schoenfeld M, Myers RH, Berkman B, et al. Potential impact of a predictive test on the gene frequency of Huntington's disease. Am J Med Genet 1984;18:423-9.
    • (1984) Am J Med Genet , vol.18 , pp. 423-429
    • Schoenfeld, M.1    Myers, R.H.2    Berkman, B.3
  • 8
    • 0023180404 scopus 로고
    • Attitudes towards predictive testing in Huntington's disease: A recent survey in Belgium
    • Evers Kiebooms G, Cassiman JJ, Van den Berghe H. Attitudes towards predictive testing in Huntington's disease: a recent survey in Belgium. J Med Genet 1987;24: 275-9.
    • (1987) J Med Genet , vol.24 , pp. 275-279
    • Evers Kiebooms, G.1    Cassiman, J.J.2    Van Den Berghe, H.3
  • 9
    • 0024493002 scopus 로고
    • The motivation of at-risk individuals and their partners in deciding for or against predictive testing for Huntington's disease
    • Evers Kiebooms G, Swerts A, Cassiman JJ, et al. The motivation of at-risk individuals and their partners in deciding for or against predictive testing for Huntington's disease. Clin Genet 1989;35:29-40.
    • (1989) Clin Genet , vol.35 , pp. 29-40
    • Evers Kiebooms, G.1    Swerts, A.2    Cassiman, J.J.3
  • 10
    • 0022904060 scopus 로고
    • Attitudes of persons at risk for Huntington's disease towards predictive testing
    • Kessler S, Field T, Worth L, et al. Attitudes of persons at risk for Huntington's disease towards predictive testing. Am J Med Genet 1987;26:259-70.
    • (1987) Am J Med Genet , vol.26 , pp. 259-270
    • Kessler, S.1    Field, T.2    Worth, L.3
  • 11
    • 0022879806 scopus 로고
    • At-risk persons' attitudes toward presymptomatic and prenatal testing of Huntington's disease in Michigan
    • Markel DS, Young AB, Penney JB. At-risk persons' attitudes toward presymptomatic and prenatal testing of Huntington's disease in Michigan. Am J Med Genet 1987;26:295-305.
    • (1987) Am J Med Genet , vol.26 , pp. 295-305
    • Markel, D.S.1    Young, A.B.2    Penney, J.B.3
  • 12
    • 0022860048 scopus 로고
    • Intended use of predictive testing by those at risk for Huntington's disease
    • Meissen GJ, Berchek RL. Intended use of predictive testing by those at risk for Huntington's disease. Am J Med Genet 1987;26:283-93.
    • (1987) Am J Med Genet , vol.26 , pp. 283-293
    • Meissen, G.J.1    Berchek, R.L.2
  • 13
    • 0026675279 scopus 로고
    • Attitudes of persons at risk and their partners toward predictive testing
    • Evers-Kiebooms G, Fryns JP, Cassiman JJ, et al., eds. New York: Wiley-Liss
    • Jacopini GA, D'Amico R, Frontali M, et al. Attitudes of persons at risk and their partners toward predictive testing. In: Evers-Kiebooms G, Fryns JP, Cassiman JJ, et al., eds. Psychosocial aspects of genetic counseling. New York: Wiley-Liss, 1992:113-7.
    • (1992) Psychosocial Aspects of Genetic Counseling , pp. 113-117
    • Jacopini, G.A.1    D'Amico, R.2    Frontali, M.3
  • 14
    • 0027437616 scopus 로고
    • Attitudes towards direct predictive testing for the Huntington's disease gene
    • Babul R, Adam S, Kremer B, et al. Attitudes towards direct predictive testing for the Huntington's disease gene. JAMA 1993;270:2321-5.
    • (1993) JAMA , vol.270 , pp. 2321-2325
    • Babul, R.1    Adam, S.2    Kremer, B.3
  • 15
    • 0026692066 scopus 로고
    • Presymptomatic testing for Huntington's disease in the United Kingdom
    • Tyler A, Ball D, Craufurd D. Presymptomatic testing for Huntington's disease in the United Kingdom. BMJ 1992;304:1593-6.
    • (1992) BMJ , vol.304 , pp. 1593-1596
    • Tyler, A.1    Ball, D.2    Craufurd, D.3
  • 16
    • 0024426983 scopus 로고
    • Uptake of presymptomatic predictive testing for Huntington's disease
    • Craufurd D, Dodge A, Kerzin-Storrar L, et al. Uptake of presymptomatic predictive testing for Huntington's disease. Lancet 1989;8663:6035.
    • (1989) Lancet , vol.8663 , pp. 6035
    • Craufurd, D.1    Dodge, A.2    Kerzin-Storrar, L.3
  • 17
    • 0024541980 scopus 로고
    • Predictive testing for Huntington's disease: II. Demographic characteristics, life-style patterns, attitudes and psychosocial assessments of the first 51 test candidates
    • Bloch M, Fahy M, Fox S, et al. Predictive testing for Huntington's disease: II. Demographic characteristics, life-style patterns, attitudes and psychosocial assessments of the first 51 test candidates. Am J Med Genet 1989;32:217-24.
    • (1989) Am J Med Genet , vol.32 , pp. 217-224
    • Bloch, M.1    Fahy, M.2    Fox, S.3
  • 18
    • 0027397173 scopus 로고
    • Reluctance to undergo predictive testing: The case of Huntington's disease
    • Quaid KA, Morris M. Reluctance to undergo predictive testing: the case of Huntington's disease. Am J Med Genet 1993;45:41-5.
    • (1993) Am J Med Genet , vol.45 , pp. 41-45
    • Quaid, K.A.1    Morris, M.2
  • 19
    • 0028018162 scopus 로고
    • Predictive testing for Huntington's disease: Nonparticipants compared with participants in the Dutch program
    • Van der Steenstraten IM, Tibben A, Roos RAC, et al. Predictive testing for Huntington's disease: nonparticipants compared with participants in the Dutch program. Am J Human Genet 1994;55:618-25.
    • (1994) Am J Human Genet , vol.55 , pp. 618-625
    • Van Der Steenstraten, I.M.1    Tibben, A.2    Roos, R.A.C.3
  • 20
    • 0028922351 scopus 로고
    • Predictive testing for Huntington's disease: Risk perception, reasons for testing and psychological profile of test applicants
    • Decruyenaere M, Evers-Kiebooms G, Boogaerts A. Predictive testing for Huntington's disease: risk perception, reasons for testing and psychological profile of test applicants. Genet Couns 1995;6:1-13.
    • (1995) Genet Couns , vol.6 , pp. 1-13
    • Decruyenaere, M.1    Evers-Kiebooms, G.2    Boogaerts, A.3
  • 21
    • 0028100407 scopus 로고
    • Predictive testing for Huntington's disease: A psychologist's view
    • Kessler S. Predictive testing for Huntington's disease: a psychologist's view. Am J Med Genet 1994;54:161-6.
    • (1994) Am J Med Genet , vol.54 , pp. 161-166
    • Kessler, S.1
  • 22
    • 0007711388 scopus 로고
    • Predictive testing for Huntington's disease (HD): Differences in uptake and characteristics of linked marker and direct test cohorts
    • Adam S, Wiggins S, Lawson K, et al. Predictive testing for Huntington's disease (HD): differences in uptake and characteristics of linked marker and direct test cohorts. Am J Human Genet 1995;57(suppl):A292.
    • (1995) Am J Human Genet , vol.57 , Issue.SUPPL.
    • Adam, S.1    Wiggins, S.2    Lawson, K.3
  • 23
    • 0026463796 scopus 로고
    • The psychological consequences of predictive testing for Huntington's disease
    • Wiggins S, Whyte P, Huggins M, et al. The psychological consequences of predictive testing for Huntington's disease. N Engl Med 1992;327:1401-5.
    • (1992) N Engl Med , vol.327 , pp. 1401-1405
    • Wiggins, S.1    Whyte, P.2    Huggins, M.3
  • 24
    • 0030635987 scopus 로고    scopus 로고
    • Predictors of psychological adjustment to genetic testing for Huntington's disease
    • Codori AM, Slavney PR, Young C, et al. Predictors of psychological adjustment to genetic testing for Huntington's disease. Health Psychol 1997;16:36-50.
    • (1997) Health Psychol , vol.16 , pp. 36-50
    • Codori, A.M.1    Slavney, P.R.2    Young, C.3
  • 25
    • 0024846048 scopus 로고
    • Optimistic biases about personal risks
    • Weinstein ND. Optimistic biases about personal risks. Science 1989;246:1232-3.
    • (1989) Science , vol.246 , pp. 1232-1233
    • Weinstein, N.D.1
  • 26
    • 0348183049 scopus 로고
    • Effects of optimism on psychological and physical well-being: Theoretical overview and empirical update
    • Scheier MF, Carver CS. Effects of optimism on psychological and physical well-being: theoretical overview and empirical update. Cognit Ther Res 1992;16:201-8.
    • (1992) Cognit Ther Res , vol.16 , pp. 201-208
    • Scheier, M.F.1    Carver, C.S.2
  • 27
    • 0029766883 scopus 로고    scopus 로고
    • Prediction of psychological functioning one year after the predictive test for Huntington's disease and impact of the test result on reproductive decision making
    • Decruyenaere M, Evers-Kiebooms G, Boogaerts A. Prediction of psychological functioning one year after the predictive test for Huntington's disease and impact of the test result on reproductive decision making. J Med Genet 1996; 33:737-43.
    • (1996) J Med Genet , vol.33 , pp. 737-743
    • Decruyenaere, M.1    Evers-Kiebooms, G.2    Boogaerts, A.3
  • 28
    • 0028034011 scopus 로고
    • Psychological effects of presymptomatic DNA testing for Huntington's disease in the Dutch program
    • Tibben A, Duivenvoorden HJ, Niermeijer MF, et al. Psychological effects of presymptomatic DNA testing for Huntington's disease in the Dutch program. Psychosom Med 1994;56:526-32.
    • (1994) Psychosom Med , vol.56 , pp. 526-532
    • Tibben, A.1    Duivenvoorden, H.J.2    Niermeijer, M.F.3
  • 29
    • 0025021343 scopus 로고
    • Relationship between hopelessness and ultimate suicide: A replication with psychiatric outpatients
    • Beck A, Brown G, Berchick RJ, et al. Relationship between hopelessness and ultimate suicide: a replication with psychiatric outpatients. Am J Psychiatry 1990;147:190-5.
    • (1990) Am J Psychiatry , vol.147 , pp. 190-195
    • Beck, A.1    Brown, G.2    Berchick, R.J.3
  • 30
    • 0027501735 scopus 로고
    • Presymptomatic DNA testing for Huntington's disease: Identifying the need for psychological intervention
    • Tibben A, Duivenvoorden HJ, Vegter-van der Vlis M, et al. Presymptomatic DNA testing for Huntington's disease: identifying the need for psychological intervention. Am J Med Genet 1993;48:137-44.
    • (1993) Am J Med Genet , vol.48 , pp. 137-144
    • Tibben, A.1    Duivenvoorden, H.J.2    Vegter-van Der Vlis, M.3
  • 31
    • 0026524216 scopus 로고
    • Predictive testing for Huntington's disease in Canada: Adverse effects and unexpected results in those receiving a decreased risk
    • Huggins M, Bloch M, Wiggins S, et al. Predictive testing for Huntington's disease in Canada: adverse effects and unexpected results in those receiving a decreased risk. Am J Med Genet 1992;42:508-15.
    • (1992) Am J Med Genet , vol.42 , pp. 508-515
    • Huggins, M.1    Bloch, M.2    Wiggins, S.3
  • 32
    • 0030636102 scopus 로고    scopus 로고
    • Three year follow up after presymptomatic testing for Huntington's disease in tested individuals and partners
    • Tibben A, Timman R, Bannink EC, et al. Three year follow up after presymptomatic testing for Huntington's disease in tested individuals and partners. Health Psychol 1997;16:20-35.
    • (1997) Health Psychol , vol.16 , pp. 20-35
    • Tibben, A.1    Timman, R.2    Bannink, E.C.3
  • 33
    • 0029007707 scopus 로고
    • Exploration of the effects of predictive testing for Huntington's disease on intimate relationships
    • Quaid KA, Wesson MK. Exploration of the effects of predictive testing for Huntington's disease on intimate relationships. Am J Med Genet 1995;57:46-51.
    • (1995) Am J Med Genet , vol.57 , pp. 46-51
    • Quaid, K.A.1    Wesson, M.K.2
  • 35
    • 0026441237 scopus 로고
    • Genetic testing for Huntington's disease: A family issue
    • Hayes CV. Genetic testing for Huntington's disease: a family issue. N Engl J Med 1992;327:1449-51.
    • (1992) N Engl J Med , vol.327 , pp. 1449-1451
    • Hayes, C.V.1
  • 36
    • 19244362641 scopus 로고    scopus 로고
    • Adverse psychological effects occurring in the first year after predictive testing for Huntington's disease
    • Lawson K, Wiggins S, Green T, et al. Adverse psychological effects occurring in the first year after predictive testing for Huntington's disease. J Med Genet 1996;33:856-62.
    • (1996) J Med Genet , vol.33 , pp. 856-862
    • Lawson, K.1    Wiggins, S.2    Green, T.3
  • 37
    • 4243238675 scopus 로고    scopus 로고
    • A survey of catastrophic events following predictive testing for Huntington's disease
    • Bloch M, Adam S, Hayden M. A survey of catastrophic events following predictive testing for Huntington's disease. Am J Med Genet 1996;57(suppl):A333.
    • (1996) Am J Med Genet , vol.57 , Issue.SUPPL.
    • Bloch, M.1    Adam, S.2    Hayden, M.3
  • 38
    • 0030903164 scopus 로고    scopus 로고
    • Psychological consequences of presymptomatic testing for Huntington's disease
    • Mlynik Szmid A. Psychological consequences of presymptomatic testing for Huntington's disease. Lancet 1997;349: 808.
    • (1997) Lancet , vol.349 , pp. 808
    • Mlynik Szmid, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.