Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block

European Journal of Immunology

Volumn 30, Issue 10, 2000, Pages 2782-2790

  Eftekhari, Pierre ^a   Sallé, Laurent ^b   Lezoualc'h, Frank ^c   Mialet, Jeanne ^c   Gastineau, Monique ^c   Briand, Jean Paul ^a   Isenberg, David A ^d   Fournié, Gilbert J ^c   Argibay, Jorge ^b   Fischmeister, Rodolphe ^c   Muller, Sylviane ^a   Hoebeke, Johan ^a  

^a INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CNRS   (France)

^c INSERM   (France)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

5 HT4 serotonin receptor; Congenital heart block; Cross reactivity; Neonatal lupus; Ro52; SSA

Indexed keywords

AUTOANTIBODY; CALCIUM CHANNEL; EPITOPE; RIBONUCLEOPROTEIN ANTIBODY; SEROTONIN 4 RECEPTOR; SYNTHETIC PEPTIDE;

ANTIBODY AFFINITY; ANTIBODY BLOOD LEVEL; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNITY; CONGENITAL HEART BLOCK; CONTROLLED STUDY; CROSS REACTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; AGED; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, ANTINUCLEAR; ANTIBODY SPECIFICITY; AUTOANTIGENS; AUTOIMMUNE DISEASES; CALCIUM CHANNELS; CHO CELLS; CRICETULUS; CROSS REACTIONS; FEMALE; HAMSTERS; HEART BLOCK; HUMAN; IMMUNITY, MATERNALLY-ACQUIRED; INFANT, NEWBORN; ION CHANNEL GATING; ION TRANSPORT; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; MYOCARDIUM; PEPTIDE FRAGMENTS; PREGNANCY; PREGNANCY COMPLICATIONS; RABBITS; RECEPTORS, SEROTONIN; RECOMBINANT FUSION PROTEINS; RIBONUCLEOPROTEINS; SUPPORT, NON-U.S. GOV'T; TRANSFECTION;

EID: 0033785022     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200010)30:10<2782::AID-IMMU2782>3.0.CO;2-9     Document Type: Article

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