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Volumn 48, Issue 10, 2000, Pages 1567-1569
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Enantioselective synthesis of the key intermediate of the acyl-CoA: Cholesterol acyltransferase (ACAT) inhibitor (R-106578) using 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (BINAP)-Ru(OAc)2 as a catalyst
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Author keywords
(R) BINAP Ru(OAc)2; ACAT inhibitor; Coumarin derivative; Enantioselective hydrogenation
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Indexed keywords
2,2' BIS(DIPHENYLPHOSPHINO) 1,1' BINAPHTHYL DERIVATIVE;
3 (2,4 DIMETHOXYPHENYL)OCT 2 ENOIC ACID;
4 N PENTYL 7 HYDROXYCOUMARIN;
ALKENE DERIVATIVE;
ANTILIPEMIC AGENT;
CHOLESTEROL ACYLTRANSFERASE INHIBITOR;
COUMARIN DERIVATIVE;
METHANOL;
PHOSPHINE DERIVATIVE;
R 106578;
RUTHENIUM COMPLEX;
UNCLASSIFIED DRUG;
ARTICLE;
ATHEROSCLEROSIS;
CATALYST;
DRUG SYNTHESIS;
ENANTIOMER;
HYDROGENATION;
HYPERLIPIDEMIA;
PRESSURE;
STEREOCHEMISTRY;
TEMPERATURE;
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EID: 0033783763
PISSN: 00092363
EISSN: None
Source Type: Journal
DOI: 10.1248/cpb.48.1567 Document Type: Article |
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Times cited : (10)
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References (17)
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