Single tube melting temperature assay for rapid and sensitive detection of the most frequent hemocromatosis mutations, C282Y and H63D

Haematologica

Volumn 85, Issue 9, 2000, Pages 990-991

  Marziliano, N ^a   Bevilacqua, E ^a   Pirulli, D ^a   Spano, A ^a   Amoroso, A ^a   Crovella, S ^a  

^a INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

Author keywords

Hemochromatosis; HFE; Melting temperature; Mutation detection

Indexed keywords

DNA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE AMPLIFICATION; GENE MUTATION; GENETIC DISORDER; GENOTYPE; HEMOCHROMATOSIS; HUMAN; MELTING POINT; POLYMERASE CHAIN REACTION;

DNA MUTATIONAL ANALYSIS; GENOTYPE; HEMOCHROMATOSIS; HUMAN; MUTATION, MISSENSE; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SUPPORT, NON-U.S. GOV'T; TEMPERATURE;

EID: 0033782454     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. HFE genotype in patients with hemochromatosis and other liver diseases
2. Product differentiation by analysis of DNA melting curves during the polymerase chain reaction
3. Single-tube genotyping without oligonucleotide probes