Platelet glycoprotein IIb/IIIa receptor inhibitor preserves coronary flow reserve during progressive coronary arteriostenosis in Swine

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 20, Issue 10, 2000, Pages 2309-2315

  Shen, You Tang ^a   Wiedmann, Richard T ^a   Lynch Jr , Joseph J ^a   Gould, Robert J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Aspirin; Coronary injury; Coronary reactive hyperemia; Coronary reserve; Glycoprotein IIb IIIa; Heparin

Indexed keywords

ACETYLSALICYLIC ACID; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; L 739758; SODIUM CHLORIDE; TIROFIBAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY CIRCUMFLEX BRANCH; CORONARY ARTERY OBSTRUCTION; CORONARY ARTERY THROMBOSIS; HYPEREMIA; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL; SWINE; THROMBOCYTE AGGREGATION;

EID: 0033782308     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.20.10.2309     Document Type: Article

References (27)

1. Coronary artery, vasoconstriction routinely occurs after percutaneous transluminal coronary angioplasty
2. Intense microvascular constriction after angioplasty of acute thrombotic coronary arterial lesion
3. Intracoronary thrombus formation causes focal vasoconstriction of epicardial arteries in patients with coronary artery disease
4. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infraction
5. A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina
6. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high risk coronary angioplasty
7. Platelet glycoprotein IIb/IIIa receptor blockade and low dose heparin during percutaneous coronary revascularization
8. Randomized placebo-controlled trial of abciximab before and during coronary interventions in refractory unstable angina: The CAPTURE Study
9. Randomized placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention IMPACT-II
10. Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty
11. Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina
12. Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina
13. Non-peptide GP IIb/IIIa inhibitors: Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation
14. A quantitative study of the anatomy and distribution of coronary arteries in swine in comparison with other animals and man
15. Swine in cardiovascular research
16. Mechanism of impaired myocardial function during progressive coronary stenosis in conscious pigs: Hibernation versus stunning?
17. Myocardial reactive hyperemia in the unanesthetized dogs
18. Effects of anesthesia and open-thorax surgery on coronary vascular reserve in swine
19. Ineffective perfusion-contraction matching in conscious, chronically instrumented pigs with an extended period of coronary stenosis
20. Coronary circulation
21. Metabolic regulation of coronary blood flow
22. Regulation of coronary blood flow
23. The local control of coronary blood flow
24. Characteristics of canine coronary resistance arteries: Importance of endothelium
25. Evidence for functional 5-HT2 receptor sites on human blood platelets
26. Effects of combinations of 5-hydroxytryptamine receptor antagonists on 5-HT-induced human platelet aggregation
27. Platelet-mediated endothelium-dependent vasodilatation is impaired by platelets from patients with diabetes mellitus