Aberrant development of thymocytes in mice lacking laminin-2

Developmental Immunology

Volumn 7, Issue 2-4, 2000, Pages 179-193

  Magner, W J ^a   Chang, A C ^a   Owens, J ^a   Hong, M J P ^a   Brooks, A ^a   Coligan, J E ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Apoptosis; Dystrophic; Integrins; Laminin; Thymocytes

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; HERMES ANTIGEN; INTEGRIN RECEPTOR; INTERLEUKIN 2 RECEPTOR; MEROSIN; MUTANT PROTEIN; VERY LATE ACTIVATION ANTIGEN 6;

ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; THYMUS;

ANIMALS; APOPTOSIS; CELL ADHESION; FEMALE; FLOW CYTOMETRY; INTEGRIN ALPHA6BETA1; INTEGRINS; LAMININ; MALE; MICE; MICE, INBRED C57BL; MUSCULAR DYSTROPHIES; T-LYMPHOCYTES;

ANIMALIA;

EID: 0033781196     PISSN: 10446672     EISSN: None     Source Type: Journal    
DOI: 10.1155/2000/90943     Document Type: Article

References (38)

1. Flow cytoenzymology as a tool for rapid cell-type and cell-lineage identification of red blood cells and blast cells
2. Cell proliferation and apoptosis in prostate cancer - Correlation with pathologic stage?
3. A new nomenclature for the laminins
4. Three muscular dystrophies: Loss of cytoskeleton-extracellular matrix linkage
5. Expression of laminin-2 in the thymus and its interaction with thymocytes
6. 1 integrins mediate laminin/merosin binding and function as costimulatory molecules for human thymocyte proliferation
7. Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintanence of secondary and tertiary structure in its rod and globular domain
8. The muscular dystrophies
9. Merosin, a tissue-specific basement membrane protein, is a laminin-like protein
10. Consequences of lack of beta 1 integrin gene expression in mice
11. Integrin signaling: Specificity and control of cell survival and cell cycle progression
12. A developmental pathway revolving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
13. Onset of TCR-β gne rearrangement and role of TCR-β expression during CD3-CD4-CD8-thymocyte differentiation
14. Positive selection of CD4+ and CD8+ T cells
15. Integrins: Versatility, modulation, and signaling in cell adhesion
16. Extracellular matrix components of the mouse thymic microenvironment. III. Thymic epithelial cells express the VLA6 complex that is involved in laminin-mediated interaction with thymocytes
17. Extracellular matrix components of the mouse thymus microenvironment: Ontogenetic studies and modulation by glucocorticoid hormones
18. Merosin, a protein specific for basement membranes of Schwann cells, striated muscle, and trophoblast, is expressed late in nerve and muscle development
19. Regulation of apoptosis by integrin receptors
20. Deficiency of dystrophin-associated proteins: A common mechanism leading to muscle cell necrosis in severe childhood muscular dystrophies
21. The extracellular matrix as a cell survival factor
22. Emerging roles of caspase-3 in apoptosis
23. Development in the thymus: It takes two to tango
24. 6 Integrins participate in pro-T cell homing to the thymus
25. Laminin/VLA-6 interactions and T cell function
26. Thymic emigration: Conveyor belts or lucky dips?
27. 1) integrin receptors on T cells
28. T cell selection in the thymus
29. Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality
30. Deficiency of merosin in dystrophic dy mice and genetic linkage of laminin M chain gene to dy locus
31. Identification of a novel mutant transcript of laminin α2 chain gene responsible for muscular dystrophy and dysmyelination in dy2J mice
32. Merosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival
33. Multiple changes in VLA protein glycosylation, expression, and function occur during mouse T cell ontogeny
34. Laminins
35. Selective assembly of laminin variants by human carcinoma cells
36. Muscular dystrophies: Diseases of the dystrophin-glycoprotein complex
37. Murine muscular dystrophy caused by a mutation in the laminin α2 (Lama2) gene
38. Defective muscle basement membrane and lack of M-laminin in the dystrophic dy/dy mouse