Prostaglandin B2 delivers a co-stimulatory signal leading to T cell activation

European Cytokine Network

Volumn 11, Issue 2, 2000, Pages 293-299

  Cattan, N ^a   Mary, D ^a   Peleraux, A ^a   Mari, B ^a   Aussel, C ^a   Rossi, B ^a  

^a INSERM   (France)

Author keywords

Interleukin 2; Prostaglandin B2; T lymphocytes; Tyrosine kinase

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MESSENGER RNA; PROSTAGLANDIN B2; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; LEUKEMIA CELL LINE; MEDIATOR RELEASE; ONCOGENE C FOS; PERIPHERAL LYMPHOCYTE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL DIVISION; ENZYME ACTIVATION; GENES, FOS; HUMAN; IN VITRO; INTERLEUKIN-2; JURKAT CELLS; LYMPHOCYTE ACTIVATION; NF-KAPPA B; PROSTAGLANDINS B; PROTEIN-TYROSINE KINASE; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-2; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES;

EID: 0033778571     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Prostaglandin E inhibits the production of human interleukin-2
2. Regulation of the immune response by prostaglandins
3. Modulation of helper T cell function by prostaglandins
4. 2 inhibits IL-2 and IL-4-dependent proliferation of CTLL-2 and HT2 cells
5. 2, IL-4, and IL-10 is responsible for UV-induced systemic immune suppression
6. 2 and the increase of intracellular cAMP inhibit the expression of IL-2 receptors in human T cells
7. Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: Role of cAMP in T cell proliferation
8. Cyclic AMP suppresses interleukin-5 synthesis by human helper T cells via the down regulation of the calcium mobilization pathway
9. Human IL-2. Detection at the picomolar level by sandwich enzyme immunoassay
10. Single-step method of RNA isolation by guanidium thiocyanate-phenol-chloroform extraction
11. 2 and V937 cells
12. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
13. Direct expression cloning of vascular cell adhesion molecule-l, a cytokine-induced endothelial protein that binds to lymphocytes
14. Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages
15. ++) and stimulation of protein kinase C
16. Functionally distinct NF-κB binding sites in the immunoglobin κ and IL-2 receptor α-chain genes
17. Nuclear transcription factors that bind to elementsof the IL-2 promoter. Induction requirements in primary human T cells
18. Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: Potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins
19. NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
20. 2 receptor and receptor-coupled functions in the choroidal vasculature of the pig during development
21. Flow- and agonist-mediated nitric oxide- and prostaglandin-dependent dilatation in spinal arteries
22. 2-induced fever in young and old Long-Evans rats
23. Signaling requirements for the expression of the transactivating factor NF-AT in human T lymphocytes
24. Effects of PGA and PGB compounds on gastrointestinal tract smooth muscle from man and laboratory animals
25. 2 receptor stimulation
26. Prostaglandin F2 alpha stimulates tyrosine phosphorylation and mitogen-activated protein kinase in osteoblastic MC3T3-El cells via protein kinase C activation