PGE2 inhibits IL-2 and IL-4-dependent proliferation of CTLL-2 and HT2 cells

Cytokine

Volumn 10, Issue 4, 1998, Pages 265-274

  Gurlo, Tatyana ^a   Huang, Wei Wei ^a   Von Grafenstein, Hermann ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Interleukin 2; Interleukin 4; Prostaglandin E2; T lymphocytes

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 4; PROSTAGLANDIN E2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DOSE RESPONSE; HELPER CELL; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL DIVISION; CELL LINE; DRUG ANTAGONISM; PHYSIOLOGY;

ANIMALS; CELL DIVISION; CELL LINE; DINOPROSTONE; INTERLEUKIN-2; INTERLEUKIN-4; MICE;

EID: 0032034245     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1997.0288     Document Type: Article

References (40)

1. 1. Cantrell DA, Smith KA (1983) Transient expression of interleukin 2 receptors. Consequences for T cell growth. J Exp Med 158:1895-1911.
2. 2. Mosmann TR, Schumacher JH, Street NF, Budd R, OGarra A, Fong TA, Bond MW, Moore KW, Sher A, Fiorentino DF (1991) Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunol Rev 123:209-229.
3. 3. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL (1986) Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136:2348-2357.
4. 4. Kim J, Woods A, Becker Dunn E, Bottomly K (1985) Distinct functional phenotypes of cloned Ia-restricted helper T cells. J Exp Med 162:188-201.
5. 5. Kichtman AH, Kurt Jones EA, Abbas AK (1987) B-cell stimulatory factor 1 and not interleukin 2 is the autocrine growth factor for some helper T lymphocytes. Proc Natl Acad Sci USA 84:824-827.
6. 6. Goodwin JS, Bankhurst AD, Messner RP (1977) Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin producing suppressor cell. J Exp Med 146:1719-1734.
7. 7. Goodwin JS, Messner RP, Peake GT (1978) Prostaglandin suppression of mitogen-stimulated lymphocytes in vitro. Changes with mitogen dose and preincubation. J Exp Med 62:753-760.
8. 8. Roper RL, Phipps RP (1994) Prostaglandin E2 regulation of the immune response. Adv Prostagl Thromb Leukotr Res 22:101-111.
9. 9. Walker C, Kristensen F, Bettens F, deWeck AL (1983) Lymphokine regulation of activated (G1) lymphocytes. I. Prostaglandin E2-induced inhibition of interleukin 2 production. J Immunol 130:1770-1773.
10. 10. Snijdewint FG, Kalinski P, Wierenga EA, Bos JD, Kapsenberg ML (1993) Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 150:5321-5329.
11. 11. Hilkens CM, Vermeulen H, van Neerven RJ, Snijdewint FG, Wierenga EA, Kapsenberg ML (1995) Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin-2. Eur J Immunol 25:59-63.
12. 12. Paliogianni F, Kincaid RL, Boumpas DT (1993) Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways. J Exp Med 178:1813-1817.
13. 13. Lacour M, Arrighi JF, Muller KM, Carlberg C, Saurat JH, Hauser C (1994) cAMP up-regulates IL-4 and IL-5 production from activated CD4+ T cells while decreasing IL-2 release and NF-AT induction. Int Immunol 6:1333-1343.
14. 14. Gold KN, Weyand CM, Goronzy JJ (1994) Modulation of helper T cell function by prostaglandins. Arthritis Rheum 37:925-933.
15. 15. McArthur JG, Raulet DH (1993) CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4. J Exp Med 178:1645-1653.
16. 16. van der Pouw Kraan TC, Boeije LC, Smeenk RJ, Wijdenes J, Aarden LA (1995) Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. J Exp Med 181:775-779.
17. 17. Katamura K, Shintaku N, Yamauchi Y, Fukui T, Ohshima Y, Mayumi M, Furusho K (1995) Prostaglandin E2 at priming of naive CD4+ T cells inhibits acquisition of ability to produce IFN-gamma and IL-2, but not IL-4 and IL-5. J Immunol 155:4604-4612.
18. 18. Rincon M, Tugores A, Lopez Rivas A, Silva A, Alonso M, De Landazuri MO, Lopez Botet M (1988) Prostaglandin E2 and the increase of intracellular cAMP inhibit the expression of interleukin 2 receptors in human T cells. Eur J Immunol 18:1791-1796.
19. 19. Krause DS, Deutsch C (1991) Cyclic AMP directly inhibits IL-2 receptor expression in human T cells: expression of both p55 and p75 subunits is affected. J Immunol 146:2285-2296.
20. 20. Anastassiou ED, Paliogianni F, Balow JP, Yamada H, Boumpas DT (1992) Prostaglandin E2 and other cyclic AMP-elevating agents modulate IL-2 and IL-2R alpha gene expression at multiple levels. J Immunol 148:2845-2852.
21. 21. Depper JM, Leonard WJ, Drogula C, Kronke M, Waldmann TA, Greene WC (1985) Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Proc Natl Acad Sci USA 82:4230-4234.
22. 22. Maca RD (1983) The effects of prostaglandins on the proliferation of cultured human T lymphocytes. Immunopharmacology 6:267-277.
23. 23. Klingemann H-G, Tsoi M-S, Storb R (1986) Inhibition of prostaglandin E2 restores defective lymphocyte proliferation and cell-mediated lympholysis in recipients after allogeneic marrow grafting. Blood 68:102-107.
24. 24. Minakuchi R, Wacholtz MC, Davis LS, Lipsky PE (1990) Delineation of the mechanism of inhibition of human T cell activation by PGE2. J Immunol 145:2616-2625.
25. 25. Izuhara K, Harada N (1993) Interleukin-4 (IL-4) induces protein phosphorylation of the IL-4 receptor and association of phosphatydylinosotol 3-phosphate to the IL-4 receptor in a mouse T-cell line, HT2. J Biol Chem 268:13097-13102.
26. 26. Nelson BH, Lord JD, Greenberg PD (1996) A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells. Mol Cell Biol 16:309-317.
27. 27. Wood MJ, Sloan DJ, Dallman MJ, Charlton HM (1993) Specific tolerance to neural allografts induced with an antibody to the interleukin 2 receptor. J Exp Med 177:597-603.
28. 28. Mannie MD, Prevost KD, Marinakis CA (1995) Prostaglandin E2 promotes the induction of anergy during T helper cell recognition of myelin basic protein. Cell Immunol 160:132-138.
29. 29. Sunder Plassmann R, Majdic O, Knapp W, Holter W (1991) In vitro and in vivo activated T cells display increased sensitivity to PGE2. Cell Immunol 138:289-299.
30. 30. Bourne HR, Lichenstein LM, Melmon KL, Henney CS, Weinstein Y, Shearer GM (1974) Modulation of inflammation and immunity by cyclic AMP. Science 184:19-28.
31. 31. Coleman RA, Smith WL, Narumiya S (1994) VIII. International Union of Pharmacology classification of prostanoid receptors: properties, distribution and structure of the receptors and their subtypes. Pharmacol Rev 46:205-226.
32. 32. Breyer RM, Davis LS, Nian C, Redha R, Stillman B, Jacobson HR, Breyer MD (1996) Cloning and expression of the rabbit prostaglandin EP4 receptor. Am J Physiol 270: F485-F493.
33. 33. Goetzl EJ, An S, Smith WL (1995) Specificity of expression and effects of eicosanoid mediators in normal physiology and human disease. FASEB J 9:1051-1058.
34. 34. Li TK, Fox BS (1993) Effect of prostaglandin E2 (PGE2) on IL-3/granulocyte-macrophage colony-stimulating factor production by T helper cells. Mode of stimulation and presence of costimulation can determine response to PGE2. J Immunol 150:1680-1690.
35. 35. Bartik MM, Bauman GP, Brooks WH, Roszman TL (1994) Costimulatory signals modulate the antiproliferative effects of agents that elevate cAMP in T cells. Cell Immunol 158:116-130.
36. 36. Vercammen C, Ceuppens JL (1987) Prostaglandin E2 inhibits human T-cell proliferation after crosslinking of the CD3-Ti complex by directly affecting T cells at an early step of the activation process. Cell Immunol 104:24-36.
37. 37. Maca RD (1987) The combined effect of prostaglandin E2 and interleukin 1 on interleukin 2 production and lymphocyte proliferation. Int J Immunopharmacol 9:611-618.
38. 38. Eskandari MK, Kundel SL, Remik DG (1989) Effects of arachidonic acid metabolites and other compounds on the CTLL assay for interleukin-2. J Immunol Methods 118:85-89.
39. 39. Karasuyama H, Melchers F (1988) Establishment of mouse cell lines which constitutively produce large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur J Immunol 18:97-104.
40. 40. Maxwell SE, Delaney HD (1990) Designing Experiments and Analyzing Data, a Model Comparison Perspective. Belmont, CA: Wads worth Publishing Company.