Pharmacokinetics of ketoprofen enantiomers after intravenous administration of racemate in camels: Effect of gender

Journal of Veterinary Pharmacology and Therapeutics

Volumn 23, Issue 3, 2000, Pages 137-143

  Al Katheeri, N A ^a   Wasfi, I A ^a   Lambert, M ^b   Saeed, A ^c   Khan, I A ^c  

^a Forensic Science Laboratory Abu Dhabi   (United Arab Emirates)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c Veterinary Research Centre   (United Arab Emirates)

Author keywords

[No Author keywords available]

Indexed keywords

KETOPROFEN;

ANIMAL EXPERIMENT; ARTICLE; CAMEL; DRUG CLEARANCE; DRUG ELIMINATION; FEMALE; GENDER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RACEMIC MIXTURE; VETERINARY MEDICINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; CAMELS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HALF-LIFE; INJECTIONS, INTRAVENOUS; KETOPROFEN; MALE; METABOLIC CLEARANCE RATE; PROTEIN BINDING; SEX FACTORS; STEREOISOMERISM;

ANIMALIA; CAMELIDAE;

EID: 0033773453     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.2000.00264.x     Document Type: Article

References (42)

1. Enantioselective disposition of 2-aryl propionic acid non-steroidal anti-inflammatory drugs. IV. Ketoprofen disposition
2. Pharmacokinetics and metabolism of ketoprofen after intravenous and intramuscular administration in camels
3. Chiral inversion as a parameter for interspecies and intercompound discrepancies in enantiospecific pharmacokinetics
4. Stereospecific pharmacokinetics of free and protein-bound ketoprofen in serum and synovial fluid of horses after intravenous and intramuscular administration
5. The metabolic chiral inversion and dispositional enantioselectivity of 2-arylpropionic acids and their biological consequences
6. Ketoprofen concentration in plasma and milk after intravenous administration in dairy cattle
7. Enantioselectivite comparee de la disposition de deux anti-inflammatories non steroidiens, le ketoprofen et le carprofene, chez l'hoet l'animal
8. Stereoselectire protein binding of ketoprofen: Effect of albumin concentration and of the biological system
9. Stereoselective pharmacokinetics of ketoprofen in the rat: Influence of route of administration
10. Adverse effects of NSAIDs
11. Non compartmental analysis based on statistical moment theory
12. Factors affecting drug metabolism
13. Stereoselective high-performance liquid chromatographic analysis of ketoprofen and its acyl glucuronides in chronic renal insufficiency
14. Gender effects in pharmacokinetics and pharmacodynamics
15. The importance of stereochemistry in the clinical pharmacokinetics of the 2-arylpropionic acid nonsteroidal anti-inflammatory drugs
16. Stereoselective disposition of ketoprofen in rats
17. Clinical pharmacokinetics of ketoprofen and its enantiomers
18. The metabolic fate of ketoprofen in the horse after oral and intramuscular administration
19. Passage of S-(+)- and R-(-)- ketoprofen across the human isolated perfused placenta
20. Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modeling
21. Infuence of formulation on the pharmacokinetics and bioavailability of racemic ketoprofen in horses
22. Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves
23. Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in the horse
24. Pharmacokinetics of ketoprofen enantiomers in monkeys following single and multiple oral administration
25. Stereoselective metabolism of anti-inflammatory 2-arylpropionates
26. Stereoselectivity of biliary excretion of 2-arylpropionates in rats
27. Stereoselective metabolism of 2-phenylpropionic acid in rat. 1) In vitro studies on the stereoselective isomerization and glucuroindation of 2-phenylpropionic acid
28. Total and free ketoprofen in serum and synovial fluid after intramuscular injection
29. Pharmacokinetics of ketoprofen in the donkey (Equus asinus)
30. Ketoprofen pharmacokinetics in the camel (Camelus deromedarius)
31. Pharmacokinetics of ketoprofen in healthy horses and horses with acute synovitis
32. Gender related differences in the pharmacokinetics of ketoprofen enantiomers in the rat
33. Metabolism of carprofen, a non-steroidal anti-inflammatory agent, in rats, dogs and human
34. Stereoselective pharmacokinetics and inversion of (R)-ketoprofen in healthy volunteers
35. Pharmacokinetics of ketoprofen after multiple intravenous doses to mares
36. Pharmacokinetics of ketoprofen in rats. Effect of age and dose
37. Comparative metabolism of R (-)-fenoprofen in rats and sheep
38. Enantioselective glucuronidation and subsequent biliary excretion of carprofen in horses
39. Formation of glycine conjugate and (-)- and (+)-enantiomers from (+)-(S)-2-phenylpropionic acid suggesting the formation of the CoA thioester intermediate in dogs
40. Pharmacokinetics of phenylbutazone in camels
41. Pharmacokinetics, metabolism and urinary detection time of flunixin after intravenous administration in camels
42. Pharmacokinetics of tolfenamic acid and its detection time in urine after intravenous administration of the drug in camels (Camelus dromedrius)