Inhibition of cholesteryl ester transfer protein by substituted dithiobisnicotinic acid dimethyl ester: Involvement of a critical cysteine

Journal of Lipid Research

Volumn 41, Issue 10, 2000, Pages 1604-1614

  Hope, Heidi Rath ^a   Heuvelman, Deborah ^e   Duffin, Kevin ^b   Smith, Christine ^a   Zablocki, Jeffery ^c   Schilling, Roger ^d   Hegde, Shridhar ^c   Lee, Len ^c   Witherbee, Bryan ^e   Baganoff, Mark ^a   Bruce, Can ^f   Tall, Alan R ^f   Krul, Elaine ^e   Glenn, Kevin ^e   Connolly, Daniel T ^e  

^a Biochemistry and Molecular Biology   (United States)

^b Analytical Sciences   (United States)

^c Chemical Sciences   (United States)

^d Pharmacia   (United States)

^e Pharmacia   (United States)

^f Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Disulfide mapping; HDL; LC MS; LDL

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; CYSTEINE; DITHIOBISNICOTINIC ACID DIMETHYL ESTER; DITHIOTHREITOL; NICOTINIC ACID ESTER; PROTEIN INHIBITOR; SC 71952; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL STRUCTURE; DISULFIDE BOND; ENZYME INHIBITION; HYDROPHOBICITY; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHROMATOGRAPHY, LIQUID; CYSTEINE; DISULFIDES; DITHIOTHREITOL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOPROTEINS; HUMANS; KINETICS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; NICOTINIC ACIDS; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN BINDING; SULFIDES; TIME FACTORS;

EID: 0033771151     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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