Reduced expression of manganese superoxide dismutase mRNA may correlate with invasiveness in esophageal carcinoma

Oncology

Volumn 59, Issue 3, 2000, Pages 223-228

  Toh, Yasushi ^a   Kuninaka, Shinji ^a   Mori, Masaki ^b   Oshiro, Tatsuro ^a   Ikeda, Yasuharu ^a   Nakashima, Hideaki ^a   Baba, Hideo ^a   Kohnoe, Shunji ^a   Okamura, Takeshi ^a   Sugimachi, Keizo ^c  

^a NATIONAL KYUSHU CANCER CENTER   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Esophageal carcinoma; Manganese superoxide dismutase; mRNA expression; Vessel invasion

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; SUPEROXIDE;

ANTIOXIDANT ACTIVITY; ARTICLE; CALCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; ENZYME ACTIVITY; ESOPHAGUS CARCINOMA; ESOPHAGUS MUCOSA; FEMALE; HUMAN; HUMAN TISSUE; INVASIVE CARCINOMA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TUMOR DIFFERENTIATION;

EID: 0033768576     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012165     Document Type: Article

References (37)

1. Aspects of the structure, function, and applications of superoxide dismutase
2. Biosynthesis and regulation of superoxide dismutases
3. Molecular genetics of superoxide dismutases
4. Antioxidant defense mechanisms: From the beginning to the end (of the beginning)
5. Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation
6. Overexpression of manganese-containing superoxide dismutase confers resistance to the cytotoxicity of tumor necrosis factor alpha and/or hyperthermia
7. Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
8. Role of antioxidant enzymes in cell immortalization and transformation
9. Antioxidant enzyme levels in cancer
10. Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells
11. Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase
12. Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma SCC-25 cells
13. Suppression of fibrosarcoma metastasis by elevated expression of manganese superoxide dismutase
14. Manganese-containing superoxide dismutase overexpression causes phenotypic reversion in SV40-transformed human lung fibroblasts
15. Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells
16. Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase
17. Manganese superoxide dismutase expression in human central nervous system tumors
18. Reactivity of a monoclonal antibody to manganese superoxide dismutase with human ovarian carcinoma
19. Manganese superoxide dismutase expression correlates with p53 status and local recurrence of cervical carcinoma treated with radiation therapy
20. Manganese superoxide dismutase content and localization in human thyroid tumors
21. Elevated serum manganese superoxide dismutase in acute leukemias
22. Detection of cancer micrometastases in lymph nodes by reverse transcription-polymerase chain reaction
23. Overexpression of manganese superoxide dismutase selectively modulates the activity of Jun-associated transcription factors in fibrosarcoma cells
24. Regulation of manganese superoxide dismutase and other antioxidant genes in normal and leukemic hematopoietic cells and their relationship to cytotoxicity by tumor necrosis factor
25. Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells
26. Lowered superoxide dismutase in highly metastatic B16 melanoma cells
27. Superoxide dismutase in SAS human tongue carcinoma cell line is a factor defining invasiveness and cell motility
28. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
29. Oxygen radicals and signaling
30. Antioxidant and redox regulation of gene transcription
31. Expression of manganese superoxide dismutase in esophageal and gastric cancers
32. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-κB and activated protein-1
33. Enzyme-linked immunosorbent assay for human manganese-containing superoxide dismutase and its content in lung cancer
34. Enhancement of superoxide dismutase activity in cancer cell lines by anticancer drugs
35. Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase transgene
36. Role of manganese superoxide dismutase in radioprotection using gene transfer studies
37. Guidelines for the clinical and pathological studies on carcinoma of the esophagus