Purification of a diagnostic, secreted cysteine protease-like protein from the hookworm Ancylostoma caninum

Parasitology International

Volumn 49, Issue 4, 2000, Pages 327-333

  Loukas, Alex ^a,b   Dowd, Andrew J ^a,c   Prociv, Paul ^b   Brindley, Paul J ^a,d  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c DUBLIN CITY UNIVERSITY   (Ireland)

^d TULANE UNIVERSITY   (United States)

Author keywords

Ac68; Ancylostoma caninum; Cysteine protease; Eosinophilic enteritis

Indexed keywords

ABC TRANSPORTER; CYSTEINE PROTEINASE; HELMINTH PROTEIN; PROTEIN AC68; PROTEIN ACCP1; SYNTHETASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANCYLOSTOMA CANINUM; ANCYLOSTOMIASIS; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CONTROLLED STUDY; EOSINOPHILIC GASTROENTERITIS; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PURIFICATION; SERODIAGNOSIS;

AMINO ACID SEQUENCE; ANCYLOSTOMA; ANCYLOSTOMIASIS; ANIMALS; ANTIBODIES, HELMINTH; CHROMATOGRAPHY; CYSTEINE ENDOPEPTIDASES; DOGS; ENTERITIS; HELMINTH PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT;

ANCYLOSTOMA CANINUM; ANCYLOSTOMATOIDEA; VERMES;

EID: 0033767859     PISSN: 13835769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5769(00)00054-4     Document Type: Article

References (29)

1. Human eosinophilic enteritis caused by dog hookworm Ancylostoma caninum
2. Dog hookworm: A cause of eosinophilic enterocolitis in humans
3. Human enteric infection with Ancylostoma caninum: Hookworms reappraised in the light of a 'new' zoonosis
4. Occult enteric infection by Ancylostoma caninum: A previously unrecognized zoonosis
5. A distinctive aphthous ileitis linked to Ancylostoma caninum
6. Eosinophilic enteritis - A recent north Queensland experience
7. Detection of antibodies to secretions of Ancylostoma caninum in human eosinophilic enteritis
8. Immunologic incrimination of Ancylostoma caninum as a human enteric pathogen
9. Immunoglobulin G subclass antibodies against excretory/secretory antigens of Ancylostoma caninum in human enteric infections
10. Characterisation of an immunodominant glycoprotein antigen of Onchocerca volvulus with homologues in other filarial nematodes and Caenorhabditis elegans
11. Characterization of Trichinella spiralis antigens sharing an immunodominant, carbohydrate-associated determinant distinct from phosphorylcholine
12. Immune responses of cattle to biochemically modified antigens from the midgut of the cattle tick Boophilus microplus
13. Detection of monoclonal antibodies specific for carbohydrate epitopes using periodate oxidation
14. CpABC, a Cryptosporidium parvum ATP-binding cassette protein at the host-parasite boundary in intracellular stages
15. Structural and functional analysis of the LaMDR1 multidrug resistance gene in Leishmania amazonesis
16. Purification and characterization of S-linalool synthase, and enzyme involved in the production of floral scent in Clarkia breweri
17. The C. elegans vitellogenin genes: Short sequence repeats in the promoter regions and homology to the vertebrate genes
18. Characterization and localization of cathepsin B proteinases expressed by adult Ancylostoma caninum hookworms
19. Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme
20. Purification and biochemical characterization of a novel cysteine protease of Entamoeba histolytica
21. Secretion of cysteine proteinase activity by the zoonotic hookworm Ancylostoma caninum
22. Immuno-histochemical localization of excretory/secretory antigens in adult Ancylostoma caninum using monoclonal antibodies and infected human sera
23. Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum
24. A developmentally regulated cysteine protease gene family in Haemonchus contortus
25. Isolation and characterization of four developmentally regulated cathepsin B-like cysteine protease genes from the nematode Caenorhabditis elegans
26. Proteolytic activities that mediate apoptosis
27. The cysteine protease activity of the major dust mite allergen Der p 1 selectively enhances the immunoglobulin E antibody response
28. Grass group I allergens (beta-expansins) are novel, papain-related proteinases