Accelerated assessing of antisense RNA efficacy using a chimeric enhanced green fluorescent protein-antisense RNA-producing vector

Antisense and Nucleic Acid Drug Development

Volumn 10, Issue 5, 2000, Pages 401-408

  Dittmar, T ^a   Schafer, F ^a   Brandt, B H ^b   Zanker, K S ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; COMPLEMENTARY RNA; GREEN FLUORESCENT PROTEIN;

ARTICLE; CLONING VECTOR; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REPORTER GENE; RNA SEQUENCE;

EID: 0033767629     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.2000.10.401     Document Type: Article

References (20)

1. Liposome-mediated in vivo gene transfer of antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity
2. Reduction of erbB2 gene product in mamma carcinoma cell lines by erbB2 mRNA-specific and tyrosine kinase consensus phosphorothioate antisense oligonucleotides
3. c-erbB-2/EGFR as dominant heterodimerization partners determine a motogenic phenotype in human breast cancer cells
4. Inhibition of tumorigenicity in lung adenocarcinoma cells by c-erbB-2 antisense expression
5. Green fluorescent protein as a marker for gene expression
6. erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification
7. Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium
8. Green light for antisense: Detection of antisense/sense RNA complex by a chimeric enhanced GFP+HER2/neu-antisense RNA producing vector
9. Expression of the apoptosis inhibitor, survivin, in nonmelanoma skin cancer and gene targeting in a keratinocyte cell line
10. Recombinant AAV-2 harboring gfp-antisense/ribozyme fusion sequences monitor transduction, gene expression, and anti-HIV-1 efficacy
11. Inhibition of thymidine kinase gene expression by antisense RNA: A molecular approach to genetic analysis
12. Stable reduction of thymidine kinase activity in cells expressing high levels of antisense RNA
13. Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms
14. Proteins specified by avian erythroblastosis virus: Coding region localization and identification of a previously undetected erb-B polypeptide
15. Induction of multidrug resistance (MDR) by transfection of MCF-10A cell line with c-Ha-ras and c-erbB-2 oncogenes
16. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
17. Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay
18. C-erbB-2 anti-sense phosphorothioate oligodeoxynucleotides inhibit growth and serum-induced cell spreading of p185(c-erbB-2)-overexpressing ovarian carcinoma cells
19. Reduction of EGF receptor levels in human tumor cells transfected with an antisense RNA expression vector
20. Dual color microscopic imagery of cells expressing the green fluorescent protein and a red-shifted variant