Homeobox genes in the genetic control of eye development

International Journal of Developmental Biology

Volumn 44, Issue 6, 2000, Pages 627-636

  Lupo, G ^a   Andreazzoli, M ^a   Gestri, G ^a   Liu, Y ^a   He, R Q ^a   Barsacchi, G ^a  

^a Dipto di Fisiologia e Biochimica   (Italy)

Author keywords

Eye field; Eye polarity; Homeobox genes; rx1; vax2

Indexed keywords

GENE PRODUCT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SPECIFICITY; CONTROLLED STUDY; EMBRYO; EMBRYO PATTERN FORMATION; EMBRYO POLARITY; EYE DEVELOPMENT; GENETIC CONSERVATION; GENETIC REGULATION; HOMEOBOX; MORPHOGENESIS; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; VERTEBRATE; XENOPUS;

ANIMALS; CELL DIVISION; CELL LINEAGE; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; MODELS, BIOLOGICAL; PROSENCEPHALON; RETINA; XENOPUS; XENOPUS PROTEINS;

EID: 0033765110     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (69)

1. Role of Xrx1 in Xenopus eye and anterior brain development
2. A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis
3. Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain
4. The homeodomain protein Vax1 is required for axon guidance and major tract formation in the developing forebrain
5. Sonic hedgehog controls epaxial muscle determination through Myf5 activation
6. XBF-1, a winged helix transcription factor with dual activity, has a role in positioning neurogenesis in Xenopus competent ectoderm
7. Pax6 in development and evolution
8. Xrx1, a novel Xenopus homeobox gene expressed during eye and pineal gland development
9. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
10. Pax6 induces ectopic eyes in a vertebrate
11. Expression of three Rx homeobox genes in embryonic and adult zebrafish
12. The specification of the retino-tectal projection in the chick
13. twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development
14. Eye development: Governed by a dictator or a junta?
15. Fate of the anterior neural ridge and the morphogenesis of the Xenopus forebrain
16. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in regulation of CNS polarity
17. Isolation of a Drosophila homolog of the vertebrate homeobox gene Rx and its possible role in brain and eye development
18. Sonic hedgehog: A common signal for ventral patterning along the rostrocaudal axis of the neural tube
19. rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina
20. Pax6 mastering eye morphogenesis and eye evolution
21. The EGF-CFC protein one-eyed pinhead is essential for nodal signaling
22. Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system
23. Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain
24. Mutations affecting morphogenesis during gastrulation and tail formation in the Zebrafish, Danio Rerio
25. Mammalian and Drosophila dachshundgenes are related to the Ski proto-oncogene and are expressed in eye and limb
26. The Shh signaling pathway in early tooth development
27. Notochord repression of endodermal Sonic hedgehog permits pancreas development
28. Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development
29. Mouse small eye results from mutations in a paired-like homeobox-containing gene
30. Retinoic acid establishes ventral retinal characteristics
31. Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk
32. Overexpression of the forebrain-specific homeobox gene Six3 induces rostral forebrain enlargement in zebrafish
33. Tbx5 and retinotectum projection
34. The evolution of eyes
35. The specification of dorsal cell fate in the vertebrate central nervous system
36. A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate
37. Six3 overexpression initiates the formation of ectopic retina
38. Six9 (Optx2), a new member of the six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development
39. Heads or tails? Retinoic acid will decide
40. Retinoic acid is necessary for development of the ventral retina in zebrafish
41. The Rx homeobox gene is essential for vertebrate eye development
42. Retinoic acid synthesis in the developing retina
43. Asymmetrical retinoic acid synthesis in the doreoventral axis of the retina
44. Dorsal and ventral retinoic territories defined by retinoic acid synthesis, breakdown and nuclear receptor expression
45. The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain
46. Midline signaling is required for Pax gene regulation and patterning of the eyes
47. Spatially and temporally restricted expression of Pax2 during murine neurogenesis
48. Expression of the Vax family homeobox genes suggests multiple roles in eye development
49. Identification of chick rax/Rx genes with overlapping patterns of expression during early eye and brain development
50. Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
51. Homeobox genes and connective tissue patterning
52. The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions
53. A posteriorizing factor, retinoic acid, reveals that anteroposterior patterning controls the timing of neuronal differentiation in Xenopus neuroectoderm
54. Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans
55. cyclops encodes a nodal-related factor involved in midline signaling
56. Sonic hedgehog mediates the polarizing activity of the ZPA
57. Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
58. Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signaling
59. Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map
60. Inductive interactions direct early regionalization of the mouse forebrain
61. Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila
62. Unique topographic separation of two spectral classes of cones in the mouse retina
63. Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region
64. The Optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes
65. A conserved blueprint for the eye?
66. Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly
67. Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode
68. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation
69. Giant eyes in Xenopus laevis by overexpressior of XOptx2