Targeted disruption of the cation-dependent or cation-independent mannose 6-phosphate receptor does not decrease the content of acid glycosidases in the acrosome

Journal of Andrology

Volumn 21, Issue 6, 2000, Pages 944-953

  Chayko, Catherine A ^a   Orgebin Crist, Marie Claire ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acrosomal enzymes; Acrosomal targeting; Mouse; Testicular germ cells

Indexed keywords

ACETYLGLUCOSAMINIDASE; ALPHA MANNOSIDASE; ANTIBODY; BETA GALACTOSIDASE; ENZYME PRECURSOR; GLYCOSIDASE; HYDROLASE; SOMATOMEDIN B RECEPTOR;

ACROSOME; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; GENE; GENE DISRUPTION; GENE MUTATION; GERM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACROSOME; ANIMALS; BETA-GALACTOSIDASE; CATIONS; CROSSES, GENETIC; EPIDIDYMIS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTOR, IGF TYPE 2; SPERMATOZOA; TESTIS;

EID: 0033764792     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1939-4640.2000.tb03426.x     Document Type: Article

References (50)

1. Lysosomal enzymes in the acrosome and their possible role in fertilization
2. Acrosome biogenesis begins during meiosis: Evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesis
3. The mammalian spermatozoon: Structure and temporal assembly
4. Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice
5. Two proteins targeted to the same lytic granule compartment undergo very different posttranslational processing
6. Glycoprotein synthesis in the Golgi apparatus of spermatids during speriogenesis of the rat
7. The spermatozoon
8. Morphogenesis of the mammalian sperm acrosome in new perspective
9. AM67, a secretory component of the guinea pig sperm acrosomal matrix, is related to mouse sperm protein sp56 and the complement component 4-binding proteins
10. + requirements for capacitation and acrosomal exocytosis in mammalian sperm
11. Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor
12. The role of clathrin-coated vesicles in acrosome formation
13. Mannose 6-phosphate receptors in sorting and transport of lysosomal enzymes
14. Neither type of mannose 6-phosphate receptor is sufficient for targeting of lysosomal enzymes along intracellular routes
15. Structure and function of the mannose 6-phosphate/insulin-like growth factor II receptors
16. Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal enzymes
17. Isolation and characterization of the two glycosylation isoforms of low molecular weight mannose 6-phosphate receptor from bovine testis. Effect of carbohydrate components on ligand binding
18. Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds
19. Roles for mannose-6-phosphate receptors in lysosomal enzyme sorting, IGF-II binding and clathrin-coat assembly
20. Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts
21. Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes
22. Evidence for a nonlysosomal origin of the acrosome
23. Identification of two types of β-COP vesicles in the Golgi complex of rat spermatids
24. Proacrosin from rabbit epididymal spermatozoa: Purification and initial biochemical characterization
25. Re-expression of the mannose 6-phosphate receptors in receptor-deficient fibroblasts
26. Identification of hydrolase binding activities of the acrosomal matrix of hamster spermatozoa
27. The sperm acrosomal matrix contains a novel member of the pentaxin family of calcium-dependent binding proteins
28. Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium
29. Receptor-mediated endocytosis and differential synthesis of mannose 6-phosphate receptors in isolated spermatogenic and Sertoli cells
30. Expression of mannose 6-phosphate receptor messenger ribonucleic acids in mouse spermatogenic and Sertoli cells
31. Characterization of matrix domains of the hamster acrosome
32. Protein transport and organization of the developing mammalian sperm acrosome
33. The two mannose 6-phosphate receptors transport distinct complements of lysosomal proteins
34. Endocytosis in spermatids during spermiogenesis of the mouse
35. Receptor-mediated and absorptive endocytosis by male germ cells of different mammalian species
36. Rat epididymal β-D-galactosidase optimally hydrolyzes glycoprotein substrate at neutral pH
37. Ligand binding specificities of the two mannose 6-phosphate receptors
38. Mouse mutants lacking the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor are impaired by lysosomal enzyme transport: Comparison of cation-independent and cation-dependent mannose 6-phosphate receptor-deficient mice
39. Appearance of an intra-acrosomal antigen during the terminal step of speriogenesis in the rat
40. Extra-Golgi pathway of an acrosomal antigen during spermiogenesis in the rat
41. The effects of brefeldin A on acrosome formation and protein transport to the acrosome in organ cultures of rat seminiferous tubules
42. 3D topography of non-compact zone Golgi tubules in rat spermatids: A computer-assisted serial section reconstruction study
43. Sertoli cell-spermatogenic cell interaction: The insulin-like factor II/cation-independent mannose 6-phosphate receptor mediates changes in spermatogenic cell gene expression in mice
44. Changes in plasma hydrolase activities in hereditary and streptozotosin-induced diabetes
45. Purification and characterization of two forms of β-D-galactosidase from rat epididymal luminal fluid: Evidence for their role in the modification of sperm plasma membrane glycoproteins
46. Purification and characterization of rat epididymal fluid α-D-mannosidase: Similarities to sperm plasma membrane α-D-mannosidase
47. Lysosomal enzymes and their receptors
48. Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/MPR. gene
49. Brefeldin A and mannose 6-phosphate regulation of acrosomic related vesicular trafficking
50. Mammalian fertilization