Tilmicosin does not inhibit interleukin-8 gene expression in the bovine lung experimentally infected with Mannheimia (Pasteurella) haemolytica

Canadian Journal of Veterinary Research

Volumn 64, Issue 4, 2000, Pages 238-242

  Goubau, S ^a   Morck, D W ^a   Buret, A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; INTERLEUKIN 8; MESSENGER RNA; TILMICOSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CATTLE DISEASE; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; GRAM NEGATIVE INFECTION; HOST RESISTANCE; INFLAMMATION; LUNG INFECTION; MANNHEIMIA HAEMOLYTICA; NONHUMAN; RESPIRATORY TRACT INFECTION;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; CATTLE; CATTLE DISEASES; IN SITU HYBRIDIZATION; INTERLEUKIN-8; LUNG; MACROLIDES; MANNHEIMIA HAEMOLYTICA; NEUTROPHILS; PASTEURELLA INFECTIONS; TYLOSIN;

ANIMALIA; BACTERIA (MICROORGANISMS); BOS TAURUS; BOVINAE; MANNHEIMIA HAEMOLYTICA; NEGIBACTERIA; PASTEURELLA;

EID: 0033762916     PISSN: 08309000     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Gorham PE, Carroll LH, McAskill JW, et al. Tilmicosin as a single injection treatment for respiratory disease of feedlot cattle. Can Vet J 1990;31:826-829.
2. Morck DW, Merrill JK, Gard MS, Olson ME, Nation PN. Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. Can J Vet Res 1997;61: 187-192.
3. Frank GH. Pasteurellosis of cattle. In: Adlam C, Rutter JM, eds. Pasteurella and pasteurellosis. San Diego: Academic Press, 1989:179-122.
4. Chin AC, Morck DW, Merrill JK, et al. Anti-inflammatory benefits of tilmicosin in calves with Pasteurella haemolytica-infected lungs. Am J Vet Res 1998;59:765-771.
5. Umeki S. Anti-inflammatory action of erythromycin. Its inhibitory effect on neutrophil NADPH oxidase activity. Chest 1993;104:1191-1193.
6. Aoshiba K, Nagai A, Konno K. Erythromycin shortens neutrophil survival by accelerating apoptosis. Antimicrob Agents Chemother 1995;39:872-877.
7. Aoshiba K, Nagai A, Konno K. Erythromycin shortens neutrophil survival by accelerating apoptosis. Antimicrob Agents Chemother 1995;39:872-877.
8. Shoji T, Yoshida S, Sakamoto H, Hasegawa H, Nakagawa H, Amayasu H. Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma. Clin Exper Allergy 1999;29:950-956.
9. Chin AC, Lee WD, Murrin KA, et al. Tilmicosin induces apoptosis in bovine peripheral neutrophils in the presence or in the absence of Pasteurella haemolytica and promotes neutrophil phagocytosis by macrophages. Antimicrob Agents Chemother 2000;44:2465-2470.
10. Mukaida N, Harada A, Matshushima K. Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactions. Cytokine Growth Factor Rev 1998;9:9-23.
11. Baggiolini M, Loetscher P, Moser B. Interleukin-8 and the chemokine family. Int J Immunopharmacol 1995;17:103-108.
12. Morsey MA, Popowych Y, Kowalski J, et al. Molecular cloning and expression of bovine interleukin-8. Microb Pathogen 1996; 20:203-212.
13. Guide to the Care and Use of Experimental Animals. Vol. 1, 2nd ed. Ottawa: The Canadian Council on Animal Care, 1992.
14. Caswell JL, Middleton DM, Sorden SD, Gorden JR. Expression of the neutrophil chemoattractant interleukin-8 in the lesions of bovine pneumonic pasteurellosis. Vet Pathol 1998;35:124-131.
15. Dean WL, Seufert AC, Schultz GA, et al. The small nuclear RNAs for pre-mRNA splicing are coordinately regulated during oocyte maturation and early embryogenesis in the mouse. Development 1989;106:325-334.
16. Koch CC, Esteban DJ, Chin AC, et al. Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: Effects of Streptococcus pneumoniae. J Antimicrob Chemother 2000;46:19-26.
17. Kunkel SL, Lukacs NW, Strieter RM. The role of interleukin-8 in the infectious process. Ann N Y Acad Science 1994;730:134-143.
18. Bresser P, van Alphen L, Habets FJM, et al. Persisting Haemophilus influenzae strains induce lower levels of inter