Dietary zinc deficiency and expression of T lymphocyte signal transduction proteins

Canadian Journal of Physiology and Pharmacology

Volumn 78, Issue 10, 2000, Pages 823-828

  Taylor, C G ^a   Giesbrecht, J A C ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Immune function; Signal transduction; T lymphocytes; Zinc

Indexed keywords

ANIMAL CELL; CONFERENCE PAPER; IMMUNE DEFICIENCY; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ZINC DEFICIENCY;

EID: 0033762892     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y00-052     Document Type: Conference Paper

References (43)

1. Changes in cytokine production and T cell subpopulations in experimentally induced zinc-deficient humans
2. Dietary zinc deficiency and protein-energy malnutrition decrease in vitro murine T lymphocyte cell cycle progression
3. Zinc finger domains: Hypotheses and current knowledge
4. The physiological role of zinc as an antioxidant
5. T and B lymphocyte subpopulations and leukocyte terminal deoxynucleotidyl-transferase in energy-protein undernutrition
6. Zinc can increase activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes
7. Functional capacity of residual lymphocytes from zinc deficient adult mice
8. p56(lck) plays a key role in transducing apoptotic signals in T cells
9. T-lymphocyte subsets and interleukin-2 production in zinc-deficient rats
10. The effect of severe protein deficiency on serum zinc concentration of mice fed a requirement level or a very high level of dietary zinc
11. Relationship between serum zinc level and immunocompetence in protein-deficient and well-nourished weanling mice
12. Nutrition and immunity: Disruption of lymphopoiesis in zinc-deficient mice
13. The dynamic link between the integrity of the immune system and zinc status
14. Requirement for the association of p56(lck) with CD4 in antigen specific signal transduction in T cells
15. The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation
16. Plasma zinc and the clinical features of malnutrition
17. Requirement for p56(lck) tyrosine kinase activation in T cell receptor-mediated thymic selection
18. High-resolution (1.5 A) crystal structure of phospholipase C from Bacillus cereus
19. Circadian variation in rat plasma zinc and rapid effect of dietary zinc deficiency
20. Sulfhydryl oxidation down-regulates T-cell signalling and inhibits tyrosine phosphorylation of phospholipase Cγl
21. Reevaluation of zinc deficiency on concanavalin-A-induced rat spleen lymphocyte proliferation
22. Expression of T lymphocyte p56(lck), a zinc-finger signal transduction protein, is elevated by dietary zinc deficiency and caloric deficiency in mice
23. A dominant-negative transgene defines a role for p56(lck) in thymopoesis
24. Profound block in thymocyte development in mice lacking p56(lck)
25. Effect of zinc deficiency on autologous rosette-forming cells
26. Phospholipase c from Bacillus cereus, a zinc-requiring metalloenzyme
27. In vitro lymphocyte-differentiating effects of thymulin (Zn-FTS) on lymphocyte subpopulations of severely malnourished children
28. 2+
29. The regulatory domain of protein kinase C coordinates four atoms of zinc
30. Zinc-altered immune function and cytokine production
31. Is zinc deficiency a public health problem?
32. Integration of receptor-mediated signals in T cells by transmembrane adaptor proteins
33. Zinc deficiency impairs immune responses against parasitic nematode infections at intestinal and systemic sites
34. Metal binding 'finger' structures in the glucocorticoid receptor defined by site-directed mutagenesis
35. Zinc and immune function: The biological basis of altered resistance to infection
36. Zinc-controlled Th1/Th2 switch significantly determines development of diseases
37. Glutathione and immunophenotypes of T and B lymphocytes in HIV-infected individuals
38. Rat liver glutathione: Possible role as a reservior of cysteine
39. Effect of dietary zinc or copper deficiency on the primary free radical defense system in rats
40. Splenocyte glutathione and CD3-mediated cell proliferation are reduced in mice fed a protein-deficient diet
41. Interaction of the unique N-terminal region of tyrosine kinase p56(lck) with cytoplasmic domains of CD4 or CD8 is mediated by cysteine motifs
42. Signal transduction by the lymphocyte-specific tyrosine protein kinase p56(lck)
43. Protein, calories, and immune defenses