The CREM system in human spermatogenesis

Journal of Endocrinological Investigation

Volumn 23, Issue 9, 2000, Pages 578-583

  Peri, A ^a   Serio, M ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

CAMP; Signal transduction; Sterility; Transcription factors

Indexed keywords

CYCLIC AMP DERIVATIVE;

AUTOCRINE EFFECT; AZOOSPERMIA; CELL DIFFERENTIATION; CELL STRUCTURE; ENDOCRINE FUNCTION; GENE EXPRESSION; GENE REPRESSION; GERM CELL; HUMAN; MALE INFERTILITY; MEIOSIS; NONHUMAN; OLIGOSPERMIA; PARACRINE SIGNALING; REVIEW; SPERMATID; SPERMATOGENESIS; SPERMATOZOON MATURATION;

EID: 0033760541     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03343779     Document Type: Review

References (22)

1. Transcription factors responsive to cAMP
2. Role of transcription factors CREB and CREM in cAMP-regulated transcription during spermatogenesis
3. Induction of CREM activator proteins in spermatids: Down-stream targets and implications for haploid germ cell differentiation
4. Identification of a functional cAMP response element in the 5'-flanking region of the gene for transition protein 1 (TP1), a basic chromosomal protein of mammalian spermatids
5. cAMP-response element modulator τ is a positive regulator of testis angiotensin converting enzyme transcription
6. Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene
7. Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor
8. Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland
9. Rhythmic transcription and autoregulatory loops: Nuclear pace-maker CREM
10. Developmental switch of CREM function during spermatogenesis: From antagonist to activator
11. Spermiogenesis deficiency and germ cell apoptosis in CREM-mutant mice
12. Severe impairment of spermatogenesis in mice lacking the CREM gene
13. Targeted mutation of the CREB gene: Compensation within the CREB/ATF family transcription factors
14. Pituitary hormone FSH directs the CREM functional switch during spermatogenesis
15. Germ-cell specific adenosine 3'-5'-monophosphate response element modulator expression in rodent and primate testis is maintained despite gonadotropin deficiency
16. cAMP-responsive element modulator gene expression in germ cells of normo- and oligoazoospermic men
17. Testicular cAMP responsive element modulator (CREM) protein is expressed in round spermatids but is absent or reduced in men with round spermatid maturation arrest
18. Round spermatids show normal testis-specific H1t but reduced cAMP-responsive element modulator and transition protein 1 expression in men with round-spermatid maturation arrest
19. Expression of mRNA and protein of nucleoproteins during human spermiogenesis
20. Absence of cAMP responsive element modulator expression at the spermatocyte arrest stage
21. Germ cell suicide: New insights into apoptosis during spermatogenesis
22. The role of autosomal cell apoptosis regulator genes in human spermatogenesis