Cyclic adenosine 3',5'-monophosphate-responsive element modulator gene expression in germ cells of normo- and oligoazoospermic men

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 10, 1998, Pages 3722-3726

  Peri, Alessandro ^a,c   Krausz, Csilla ^a   Cioppi, Federica ^a   Granchi, Simone ^a   Forti, Gianni ^a   Francavilla, Sandro ^b   Serio, Mario ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP;

ALTERNATIVE RNA SPLICING; ARTICLE; AZOOSPERMIA; CELL MATURATION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC REGULATION; GERM CELL; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOGENESIS;

CYCLIC AMP RESPONSE ELEMENT MODULATOR; DNA-BINDING PROTEINS; GENE EXPRESSION; HUMANS; IN SITU HYBRIDIZATION; MALE; OLIGOSPERMIA; POLYMERASE CHAIN REACTION; REFERENCE VALUES; REPRESSOR PROTEINS; SPERMATOZOA; TESTIS; TRANSCRIPTION, GENETIC;

EID: 0031796080     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.10.3722     Document Type: Article

References (19)

1. Nieschlag E. 1997 Scope and goals of andrology. In: Nieschlag E, Behre HM, eds. Male reproductive health and dysfunction. Berlin: Springer; 3-8.
2. Behre HM, Kliesch S, Meschede D, Nieschlag E. 1994 Hypogonadismus und Infertilitat des Mannes. In: Gerok W, Hartmann F, Pfrcundschuh M, Philip Th, Schuster H-P, Sybrecht GW, eds. Klinik der Gegenwart, Muenchen: Urban und Schwarzenberg; vol. III, 2:1-73.
3. Sharpe RM. 1994 Regulation of spermatogenesis. In: Knobil E, Neill JD, eds. Physiology of reproduction, 2nd ed. New York: Raven Press; 1363-1434.
4. Griswold MD. 1993 Action of FSH on mammalian Sertoli cells. In: Russel LD, Griswold MD, eds. The Sertoli cell. Clearwater: Coche River; 493-508.
5. Lalli E, Lee JS, Lamas M, et al. 1996 The nuclear response to cAMP: role of transcription factor CREM. Phil Trans R Soc Lond B. 351:201-209.
6. Monaco L, Nantel F, Foulkes NS, Sassone-Corsi P. 1996 CREM: a transcriptional master switch governing the cAMP response in the testis. In: Hansson V, Levy FO, Tasken K eds. Signal transduction in testicular cells. Berlin: Springer-Verlag; 69-94.
7. Walker HW, Habener JF. 1996 Role of transcription factors CREB and CREM in cAMP-regulated transcription during spermatogenesis. Trends Endocrinol Metab. 7:133-138.
8. Sun Z, Sassone-Corsi P, Means A. 1995 Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene. Mol Cell Biol. 15:561-571.
9. Kistler M, Sassone-Corsi P, Kistler SW. 1994 Identification of a functional cAMP response element in the 5′-flanking region of the gene for transition protein 1 (TP1), a basic chromosomal protein of mammalian spermatids. Biol Reprod. 51:1322-1329.
10. Delmas V, Van Der Hoorn F, Melstoem B, et al. 1993 Induction of CREM activator proteins in spermatids: down-stream targets and implications for haploid germ cell differentiation. Mol Endocrinol. 7:1502-1514.
11. Tamai KT, Monaco, L, Nantel F, Zazopoulos E, Sassone-Corsi P. 1997 Coupling signaling pathways to transcriptional control: nuclear factors responsive to cAMP. In: Conn PM, ed. Recent Progress in Hormone Research. Bethesda, MD: The Endocrine Society; 2:121-140.
12. Laoide BM, Foulkes MS, Schloter F, et al. 1993 The functional versatility of CREM is determined by its modular structure. EMBO J. 12:1179-1191.
13. Foulkes NS, Mellstroem B, Benusiglio E, Sassone-Corsi P. 1992 Developmental switch of CREM function during spermatogenesis: from antagonist to activator. Nature. 355:80-84.
14. Nantel F, Monaco L, Foulkes N, et al. 1996 Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice. Nature. 380:159-162.
15. Blendy JA, Kaestner KH, Weinbauer GF, et al. 1996 Severe impairment of spermatogenesis in mice lacking the CREM gene. Nature. 380:162-165.
16. Dveksler GS, Basile AA, Dieffenbach CW. 1992 Analysis of gene expression: use of oligonucleotide primers for glyceraldehyde-3-phosphate dehydrogenase. PCR Methods Appl. 1:283-285.
17. Peri A, Dhanireddy R, Dubin N, et al. 1995 Uteroglobin gene expression in the rabbit uterus throughout gestation and in the fetal lung: relationship between uteroglobin and eicosanoid levels in the developing fetal lung. J Clin Invest. 96:343-353.
18. Weinbauer GF, Behr R, Bergmann M, Nieschlag E. 1998 Testicular cAMP response element modulator (CREM) protein is expressed in round spermatids but is absent or reduced in men with round spermatid maturation arrest. Mol Hum Reprod. 4:9-15.
19. Hurst S, Howes EA, Coadwell J, Jones R. 1998 Expression of a testis-specific putative actin-capping protein associated with the developing acrosome during rat spermiogenesis. Mol Reprod Dev. 49:81-91.