Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal cancer cells: Possible association with Na+, K+-ATPase

British Journal of Cancer

Volumn 83, Issue 9, 2000, Pages 1209-1215

  Iizuka, N ^a   Miyamoto, K ^a,b   Tangoku, A ^a   Hayashi, H ^a   Hazama, S ^a   Yoshino, S ^a   Yoshimura, K ^a   Hirose, K ^c   Yoshida, H ^d   Oka, M ^a  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

^c KUREHA CORPORATION   (Japan)

^d YAMAGUCHI UNIVERSITY HOSPITAL   (Japan)

Author keywords

Cisplatin; DNA damage; Mitochondrial membrane potential; nm23; Oesophageal squamous cell carcinoma

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CELL DNA; CISPLATIN; NUCLEOSIDE DIPHOSPHATE KINASE; OUABAIN;

ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DNA DAMAGE; DRUG ACCUMULATION; DRUG UPTAKE; ENZYME ACTIVITY; ESOPHAGUS CARCINOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SQUAMOUS CELL CARCINOMA;

EID: 0033760343     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1436     Document Type: Article

References (43)

1. Role of the Na+, K(+)-adenosine triphosphatase in the accumulation of cis-diamminedichloroplatinum(II) in human ovarian carcinoma cells
2. Regulation of expression of Na+, K+-ATPase in androgen-dependent and androgen-independent prostate cancer
3. Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus
4. Polymerase chain reaction analysis of cisplatin-induced mitochondrial DNA damage in human ovarian carcinoma cells
5. ATP-dependent steps in apoptotic signal transduction
6. Increased sensitivity to cisplatin by nm23-transfected tumor cell lines
7. Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines
8. MycN sensitizes neuroblastoma cells for drug-induced apoptosis
9. Tumour cells engineered to secrete interleukin- 15 augment anti-tumour immune responses in vivo
10. Immunohistochemical analysis of nm23 gene product/NDP kinase expression in pulmonary adenocarcinoma: Lack of prognostic value
11. Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer
12. NM23-H1 and NM23-H2 messenger RNA abundance in human hepatocellular carcinoma
13. The association between nm23-H1 expression and survival in patients with esophageal squamous cell carcinoma
14. The nm23-H1 gene as a predictor of sensitivity to chemotherapeutic agents in oesophageal squamous cell carcinoma
15. Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines
16. Isolation and characterization of a gene encoding rat nucleoside diphosphate kinase
17. Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay
18. Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
19. Cisplatin and etoposide in oesophageal cancer: A phase II study
20. The mitochondrial death/life regulator in apoptosis and necrosis
21. Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: Effects on tumor metastatic potential, colonization and enzymatic activity
22. NM-23 H1 immunohistochemistry is not useful as predictor of metastatic potential of colorectal cancer
23. Modulation of cis-diamminedichloroplatinum (II) accumulation and sensitivity by forskolin and 3-isobutyl-1-methylxanthine in sensitive and resistant human ovarian carcinoma cells
24. Na+ and K+ regulate the phosphorylation state of nucleoside diphosphate kinase in human airway epithelium
25. Ouabain-resistant non-small-cell lung-cancer cell line shows collateral sensitivity to cis-diamminedichloroplatinum(II) (CDDP)
26. The influence of interleukin-6 on the growth of human esophageal cancer cell lines
27. Induction of Fas-mediated apoptosis on circulating lymphocytes by surgical stress
28. Preferential binding of cisplatin to mitochondrial DNA of Chinese hamster ovary cells
29. Preferential formation and decreased removal of cisplatin-DNA adducts in Chinese hamster ovary cell mitochondrial DNA as compared to nuclear DNA
30. Gene-specific repair of Pt/DNA lesions and induction of apoptosis by the oral platinum drug JM216 in three human ovarian carcinoma cell lines sensitive and resitant to cisplatin
31. Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current
32. Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines
33. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
34. Nm23 in ovarian cancer: Correlation with clinical outcome and other clinicopathologic and biochemical prognostic parameters
35. Nm23-H1 expression in intrahepatic or extrahepatic metastases of hepatocellular carcinoma
36. Identification of a second human nm23 gene, nm23-H2
37. Evidence for a novel gene associated with low tumor metastatic potential
38. cis-diamminedichloroplatinum (ii) resistance in vitro and in vivo in human embryonal carcinoma cells
39. Reduced expression of nm23-H1, but not of nm23-H2 is concordant with the frequency of lymph node metastasis of human breast cancer
40. Expression of nm23/NDP kinase proteins on the cell surface
41. Decrease in nucleoside diphosphate kinase (NDPK/nm23) expression during hematopoietic maturation
42. Denaturing gradient gel method for mapping single base changes in human mitochondrial DNA
43. Secretion of ATP-utilizing enzymes, nucleoside diphosphate kinase and ATPase, by Mycobacterium bovis BCG: Sequestration of ATP from macrophage P2Z receptors?