The cyclic GMP-specific phosphodiesterase inhibitor, sildenafil, stimulates human sperm motility and capacitation but not acrosome reaction

Journal of Andrology

Volumn 21, Issue 6, 2000, Pages 929-937

  Lefievre, L ^a   De Lamirande, E ^a   Gagnon, C ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

cAMP; Hyperactivation; Phosphodiesterases; Tyrosine phosphorylation

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN); SILDENAFIL; TYROSINE;

ACROSOME; ACROSOME REACTION; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; HUMAN CELL; MALE; PHOSPHORYLATION; PRIORITY JOURNAL; SPERM; SPERMATOZOON CAPACITATION; SPERMATOZOON MOTILITY;

1-METHYL-3-ISOBUTYLXANTHINE; 3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ACROSOME REACTION; CYCLIC AMP; CYCLIC GMP; FEMALE; HUMANS; ISOENZYMES; MALE; PHOSPHODIESTERASE INHIBITORS; PHOSPHOPROTEINS; PIPERAZINES; SPERM CAPACITATION; SPERM MOTILITY; SUBSTRATE SPECIFICITY;

EID: 0033759441     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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