p73 Gene expression in ovarian cancer tissues and cell lines

Clinical Cancer Research

Volumn 6, Issue 10, 2000, Pages 3910-3915

  Chen, Chun Ling ^a   Ip, Sin Ming ^a   Cheng, Danny ^a   Wong, Ling Chui ^a   Ngan, Hextan Y S ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN P73;

ARTICLE; CANCER CELL CULTURE; CANCER TISSUE; DEMETHYLATION; DNA DETERMINATION; DNA METHYLATION; DNA POLYMORPHISM; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENOCARCINOMA, CLEAR CELL; ADENOCARCINOMA, MUCINOUS; ALLELES; BLOTTING, WESTERN; CARCINOMA, ENDOMETRIOID; CPG ISLANDS; CYSTADENOCARCINOMA, MUCINOUS; CYSTADENOCARCINOMA, SEROUS; CYSTADENOMA, SEROUS; DNA METHYLATION; DNA-BINDING PROTEINS; EXONS; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; LOSS OF HETEROZYGOSITY; LYMPHOCYTES; METHYLATION; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; OVARY; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0033754993     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. p53 Mutations in human cancers
2. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
3. There may be two tumor suppressor genes on chromosome arm 1p closely associated with biologically distinct subtypes of neuroblastoma
4. 1p36: Every subband a suppressor?
5. Loss of imprinting and allele switching of p73 in renal cell carcinoma
6. Activation of p73 silent allele in lung cancer
7. Overexpression of the wild type p73 gene in human bladder cancer
8. Mutation, allelotyping, and transcription analysis of the p73 gene in prostatic carcinoma
9. Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas
10. p73 At chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent
11. p73, A gene related to p53, is not mutated in esophageal carcinomas
12. Mutational and expression analysis of the p73 gene in melanoma cell lines
13. The expression of p73 is increased in lung cancer, independent of p53 gene alteration
14. Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5' CpG island methylation
15. Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation
16. Frequent loss of imprinting of the HI9 and IGF-II genes in ovarian tumors
17. Loss of imprinting of the IGF-II and HI9 genes in epithelial ovarian cancer
18. Expression of p73, a novel protein related to the p53 tumor suppressor p53, and apoptosis in cholangiocellular carcinoma of the liver
19. Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers
20. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumor
21. Relaxation of imprinted genes in human cancer
22. Imprinting of genomic domain of 11p15 and loss of imprinting in cancer: An introduction
23. p73 Competes with p53 and attenuates its response in a human ovarian cancer cell line