Hypoxia up-regulates angiopoietin-2, a Tie-2 ligand, in mouse mesangial cells

Kidney International

Volumn 58, Issue 5, 2000, Pages 1912-1919

  Hai Tao Yuan, ^a   Su Ping Yang, ^a   Woolf, A S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Angiopoietin; Endothelial cells; Hypoxia; Kidney development; Mesangium; Nephrogenesis

Indexed keywords

ANGIOPOIETIN 2; MESSENGER RNA; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; GLOMERULUS; HYPOXIA; IMMUNOHISTOCHEMISTRY; KIDNEY DEVELOPMENT; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033753391     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00363.x     Document Type: Article

References (30)

1. Distinct roles for the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
2. A molecular and genetic analysis of renal glomerular capillary development
3. Cell autonomous functions of the receptor tyrosine kinase TIE in a late phase of angiogenic capillary growth and endothelial cell survival during murine development
4. Effects of oxygen on vascular patterning in Tiel/LacZ metanephric kidneys in vitro
5. The endothelial-specific receptor tyrosine kinase, tek, is a new member of a subfamily of receptors
6. Isolation of angiopoietin-1, a ligand for the Tie-2 receptor, by secretion-trap expression cloning
7. Angiopoietin-1 induces sprouting angiogenesis in vitro
8. Chemotactic properties of the angiopoietin-1 and angiopoietin-2 ligands for the endothelial specific receptor tyrosine kinase Tie2
9. Direct actions of angiopoietin-1 on human endothelium: Evidence for network stabilisation, cell survival, and interaction with other angiogenic growth factors
10. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
11. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
12. Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggest a role in glioblastoma angiogenesis
13. Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma
14. Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia
15. Angiopoietin-2 is a site specific factor in differentiation of mouse renal vasculature
16. Hypoxia and vascular endothelial growth factor selectively upregulate angiopoietin-2 in bovine microvascular endothelial cells
17. Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation
18. Angiopoietins 3 and 4: Diverging gene counterparts in mice and humans
19. The hepatocyte growth factor/scatter factor (HGF/SF) receptor, met, transduces a morphogenetic signal in renal glomerular fibromuscular mesangial cells
20. Interaction of angiotensin II and mechanical stretch on vascular endothelial growth factor production by human mesangial cells
21. Chronic hypoxia induces proliferation of cultured mesangial cells: Role of calcium and protein kinase C
22. Effects of hypoxia on the extracellular matrix production of cultured rat mesangial cells
23. 2 production in renal cell cultures
24. Signal perception and transduction: The role of protein kinases
25. Endothelial PAS domain protein 1 (EPAS1), a transcription selectively expressed in endothelial cells
26. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
27. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes
28. Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression
29. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
30. A new model of renal microvascular endothelial injury