Testing the 3Q:1R 'Rule': Mutational analysis of the ionic 'zero' layer in the yeast exocytic SNARE complex reveals no requirement for arginine

Molecular Biology of the Cell

Volumn 11, Issue 11, 2000, Pages 3849-3858

  Katz, L ^a   Brennwald, P ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SNARE PROTEIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; EXOCYTOSIS; FUNGAL GENETICS; FUNGUS MUTATION; GENETIC ANALYSIS; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN TRANSPORT; YEAST;

FUNGI;

EID: 0033749565     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.11.11.3849     Document Type: Article

References (34)

1. Mso1p: A yeast protein that functions in secretion and interacts physically and genetically with Sec1p
2. SNAREs and the specificity of transport vesicle targeting
3. Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis
4. Sec1p binds to SNARE complexes and concentrates at sites of secretion
5. A conformational switch in syntaxin during exocytosis: Role of munc18
6. Crystal structure of GCN4-pIQI, a trimeric coiled coil with buried polar residues
7. Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly
8. Structural changes are associated with soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor complex formation
9. Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs
10. Folding intermediates of SNARE complex assembly
11. Tomosyn: A syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process
12. Neurotransmitter release: Four years of SNARE complexes
13. Springs and zippers: Coiled coils in SNARE-mediated membrane fusion
14. Genetic and morphological analyses reveal a critical interaction between the C-termini of two SNARE proteins and a parallel four helical arrangement for the exocytic SNARE complex
15. Preferential heterodimeric parallel coiled-coil formation by synthetic Max and c-Myc leucine zippers: A description of putative electrostatic interactions responsible for the specificity of heterodimerizafion
16. Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9
17. Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster
18. Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex
19. Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain
20. Regulation of SNARE complex assembly by an N-terminal domain of the t-SNARE Sso1p
21. Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway
22. Protein dissection of the antiparallel coiled coil from Escherichia coli seryl tRNA synthetase
23. Mechanism of specificity in the Fos-Jun oncoprotein heterodimer
24. The yeast SLY gene products, suppressors of defects in the essential GTP-binding Ypt1 protein, may act in endoplasmic reticulum-to-Golgi transport
25. SNAREs and the secretory pathway: Lessons from yeast
26. Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C terminus of the SNAP-25 homolog, Sec9
27. Mechanisms of intracellular protein transport
28. SNAREs contribute to the specificity of membrane fusion
29. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
30. SNAP receptors implicated in vesicle targeting and fusion
31. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
32. A conserved domain is present in different families of vesicular fusion proteins: A new superfamily
33. A model for structural similarity between different SNARE complexes based on sequence relationships
34. Membrane fusion: SNARE the rod, coil the complex