Differential expression of GP63 genes in Trypanosoma cruzi

Molecular and Biochemical Parasitology

Volumn 110, Issue 2, 2000, Pages 409-415

  Grandgenett, P M ^a   Coughlin, B C ^b   Kirchhoff, L V ^b,c   Donelson, J E ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Amastigotes; Differential gene expression; Epimastigotes; GP63; Surface protease

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA;

AMASTIGOTE; AMINO ACID SEQUENCE; ARTICLE; EPIMASTIGOTE; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TRYPANOSOMA; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, PROTOZOAN; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; TRYPANOSOMA CRUZI;

EID: 0033747246     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(00)00275-9     Document Type: Article

References (22)

1. Role of the Leishmania surface protease GP63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis
2. Extrachromosomal genetic complementation of surface metalloproteinase (GP63)-deficient Leishmania increases their binding to macrophages
3. Episomal expression of specific sense and antisense mRNAs in Leishmania amazonensis: Modulation of GP63 level in promastigotes and their infection of macrophages in vitro
4. Three distinct RNAs for the surface protease GP63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form
5. Sequence diversity and organization of the msp gene family encoding GP63 of Leishmania chagasi
6. The effect of ongoing protein synthesis on the steady state levels of GP63 RNAs in Leishmania chagasi
7. Genes encoding the major surface glycoprotein in Leishmania are tandemly linked at a single chromosomal locus and are constitutively transcribed
8. Structurally distinct genes for the surface protease of Leishmania mexicana are developmentally regulated
9. Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin (GP63)
10. African trypanosomes have differentially expressed genes encoding homologues of the Leishmania GP63 surface protease
11. Crithida fasciculata contains a transcribed leishmanial surface proteinase (GP63) gene homologue
12. A differentially expressed gene family encoding 'amastin' a surface protein of Trypanosoma cruzi amastigotes
13. Glycolipid anchoring of plasma membrane proteins
14. The crystal structure of the Leishmania major surface proteinase leishmanolysin (GP63)
15. Leishmania: Fine mapping of the leishmanolysin molecule's conserved core binding domains in binding and internalization
16. Post-transcriptional elements regulating expression of mRNAs from the amastin/tuzin gene cluster of Trypanosoma cruzi
17. Amastin mRNA abundance in Trypanosoma cruzi is controlled by a 3'-untranslated region position dependent cis-element and an untranslated region binding protein
18. Glycoprotein 46 mRNA abundance is post-transcriptionally regulated during development of Leishmania chagasi promastigotes to an infectious form
19. Metacyclogenesis is a major determinant if Leishmania promastigote virulence and attenuation
20. Indentification of an infective stage of Leishmania promastigotes
21. Growth cycle-dependent generation of complement-resistant Leishmania promastigotes
22. Control of gene expression in trypanosomes