Role of cGMP-inhibited phosphodiesterase and sarcoplasmic calcium in mediating the increase in basal heart rate with nitric oxide donors

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 10, 2000, Pages 1831-1840

  Musialek, Piotr ^a   Rigg, Lauren ^b   Terrar, Derek A ^b   Paterson, David J ^b   Casadei, Barbara ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Heart rate; Intracellular calcium; Nitric oxide signaling; Sinoatrial node

Indexed keywords

CYCLIC GMP; CYCLOPIAZONIC ACID; KT 5720; LINSIDOMINE; MILRINONE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHOSPHODIESTERASE; QUAZINONE; RYANODINE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CHRONOTROPISM; GUINEA PIG; HEART RATE; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; SINUS NODE;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0033744510     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1216     Document Type: Article

References (50)

1. Nitric oxide can increase heart rate by stimulating the hyperpolarization-activated inward current. I(f)
2. The nitric oxide donor sodium nitro-prusside increases heart rate in the absence of changes in arterial blood pressure when applied topically to the sino-atrial node in the anaesthetised pig
3. Nitric oxide donors can increase heart rate independent of autonomic activation
4. Effect of exogenous nitric oxide on baroreflex function in humans
5. Direct activation of cardiac pacemaker channels by intracellular cyclic AMP
6. A family of hyperpolarization-activated mammalian cation channels
7. Relationship between inhibition of cardiac muscle phosphodiesterases, changes in cyclic nucleotide levels, and contractile response for CI-914 and other novel cardiotonics
8. Intracellular cyclic GMP receptor proteins
9. The role of phosphorylation in the regulation of I(f) in rabbit SA node myocytes
10. Differential control of the hyperpolarization-activated current I(f) by cAMP gating and phosphatase inhibition in rabbit sino-atrial node myocytes
11. 2+ of the hyperpolarization-activated inward current in rabbit single sino-atrial node cells
12. Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway
13. Nitric oxide activates skeletal and cardiac ryanodine receptors
14. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation
15. Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes
16. Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes
17. Localization and functional significance of ryanodine receptors during beta-adrenoceptor stimulation in the guinea-pig sinoatrial node
18. The use of nitric oxide donors in pharmacological studies
19. Regulation of the cardiac ryanodine receptor by protein kinase-dependent phosphorylation
20. 2+-independent manner in cardiac myocytes: Role of troponin I phosphorylation
21. Protein kinase G is not essential to NO-cGMP modulation of basal tone in rat pulmonary circulation
22. 2+ transients in mammalian cardiac muscle
23. 2+-ATPase, on the frequency-dependence of the contraction-relaxation cycle of the guinea-pig isolated atrium
24. 2+, contraction, and potential in cardiac myocytes
25. Dual effect of nitric oxide on the hyperpolarization-activated inward current I(f) in sino-atrial cells of the rabbit
26. Differential sensitivity to cardiotonic drugs of cyclic AMP phosphodiesterases isolated from canine ventricular and sinoatrial-enriched tissues
27. Characteristics of nitric oxide-mediated cholinergic modulation of calcium current in rabbit sinoatrial node
28. The ability of denbufylline to inhibit cyclic nucleotide phosphodiesterase and its affinity for adenosine receptors and the adenosine re-uptake site
29. Pharmacology of the bipyridines: Amrinone and milrinone
30. Cyclic nucleotide phosphodiesterases as therapeutic targets in cardiovascular diseases
31. Possible role of calcium release from the sarcoplasmic reticulum in pacemaking in guinea-pig sinoatrial node
32. 2+ release from sarcoplasmic reticulum in the regulation of sinoatrial node automaticity
33. A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate
34. Intracellular calcium does not directly modulate cardiac pacemaker I(f) channels
35. 2+ on I(k) and I(f) in guinea-pig isolated sino-atrial node cells. Abstract
36. Different compartments of sarcoplasmic reticulum participate in the excitation-contraction coupling process in human atrial myocytes
37. NO induces positive inotropy through cGMP-dependent pathway: Rectification of previously misinterpreted phenomenon. Abstract
38. Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle
39. Cytosolic and sarcoplasmic reticulum-associated low K(m), cGMP-inhibited cAMP phosphodiesterase in mammalian myocardium
40. Regulation of cyclic ADP ribose (cADPR) production by protein kinase A in cardiac ventricular microsomes prepared from guinea-pig heart
41. Actions of cADP-ribose and its antagonists on contraction in guinea pig isolated ventricular myocytes. Influence of temperature
42. Effects of photoreleased cADP-ribose on calcium transients and calcium sparks in myocytes isolated from guinea pig and rat ventricle
43. Nitric oxide release from the isolated guinea pig heart
44. Mechanical transduction of nitric oxide synthesis in the beating heart
45. Changes in extracellular pH mediate the chronotropic responses to L-arginine
46. Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: Contributions of NOS isoforms to blood pressure and heart rate control
47. Prolonged sinus node recovery time in humans after the intracoronary administration of a nitric oxide synthase inhibitor
48. Elevated blood pressures in mice lacking endothelial nitric oxide synthase
49. Mechanisms of complete baroreceptor resetting in hypertension