Role of thrombomodulin in cancer biology

Breast

Volumn 9, Issue 5, 2000, Pages 264-266

  Iqbal, S ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR; FIBRINOLYTIC AGENT; THROMBOMODULIN;

BIOLOGY; BREAST CANCER; CANCER; CONTROLLED STUDY; EPITHELIUM CELL; HEMOSTASIS; HUMAN; HUMAN CELL; LYMPH VESSEL; MALIGNANT TRANSFORMATION; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; TUMOR CELL;

EID: 0033739778     PISSN: 09609776     EISSN: None     Source Type: Journal    
DOI: 10.1054/brst.2000.0186     Document Type: Review

References (24)

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2. Activation of blood coagulation in cancer; Trousseau's Syndrome revisited
3. Coagulation disorders in cancer
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6. Human thrombomodulin complete cDNA sequence and chromosome localization of the gene
7. Thrombomodulin as a marker of vascular and lymphatic tumours
8. Expression of thrombomodulin in oesophageal squamous cell carcinoma and its relationship to lymph node metastasis
9. Thrombomodulin inhibits intrahepatic spread in human hepatocellular carcinoma
10. Production of endothelin-1 and Thrombomodulin by human pancreatic cancer cells
11. Detection of Thrombomodulin in human lung cancer cells
12. Expression and localisation of thrombomodulin in preneoplastic brochial lesions and in lung cancer
13. Increased plasma Thrombomodulin in cancer patients
14. Thrombomodulin is present in human plasma and urine
15. Fibrinogen deposition without thrombin generation in primary human breast tissue
16. Thrombomodulin is a new biological prognostic marker for breast cancer: An immunohistochemical study
17. Thrombomodulin expression of primary breast cancer is a predictor of axillary lymph node metastasis
18. Fetomodulin: Marker surface protein of foetal development which is modulatable by cyclic AMP
19. Absence of blood clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
20. Thrombin stimulates tumour platelet adhesion in vitro and metastasis in vivo
21. Thrombomodulin modulates the mitogenic response to thrombin of human umbilical vein endothelial cells
22. Thrombomodulin modulates growth of tumour cells independent of its anticoagulant activity
23. Thrombospondin-I and transforming growth factor-beta 1 promote breast tumor cell invasion through up-regulation of the plasminogen/plasmin system
24. Inactivation of receptor-bound pro-urokinase-type plasminogen activator (pro-uPA) by thrombin and thrombin/thrombomodulin complex