Characterization of the endothelin receptor subtypes in human prostate

Journal of Cardiovascular Pharmacology

Volumn 36, Issue 5 SUPPL. 1, 2000, Pages

  Hiraoka, Y ^a   Oshita, M ^a   Morikawa, K ^a   Nagata, O ^a   Hahn, K J ^a   Hahn, A ^a   Okada, K ^a   Taniguchi, T ^a   Muramatsu, I ^a  

^a Abbott Japan Co Ltd   (Japan)

Author keywords

Contractile response; Endothelin receptor; Human prostate; Receptor binding experiment; Receptor subtype

Indexed keywords

DARUSENTAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR AGONIST; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; LU 224332; RECEPTOR SUBTYPE; SARAFOTOXIN S6C; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BINDING COMPETITION; DRUG EFFECT; DRUG RECEPTOR BINDING; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION; RECEPTOR AFFINITY; SMOOTH MUSCLE CONTRACTION;

EID: 0033734683     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200036001-00123     Document Type: Article

References (8)

1. A novel potent vasaconstrictor peptide produced by vascular endothelial cells
2. Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
3. Endothelin-1 in the human prostate: Tissue levels, source of production and isometric tension studies
4. Binding and functional properties of endothelin receptor subtypes in the human prostate
5. Evaluation of the effect of endothelin-1 and characterization of the selective endothelin A receptor antagonist PD155080 in the prostate
6. LU302872 and its racemate (LU224332) show balanced endothelin-A/B receptor affinity, high oral activity, and inhibit human prostate tissue contractions
7. Localization of endothelin receptors in the human prostate
8. Identification of endothelin receptors in normal and hyperplastic human prostate tissues