Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: Comparison with her mother and three control subjects

Journal of Lipid Research

Volumn 41, Issue 11, 2000, Pages 1883-1889

  Salen, G ^a   Xu, G ^a   Tint, G S ^a   Batta, A K ^a   Shefer, S ^a  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

Cholesterol; Sitostanol; Sitosterol; Stanol fatty acid esters

Indexed keywords

24 METHYLCHOLESTANOL; CHOLESTEROL; SITOSTANOL; SITOSTEROL; STEROL; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY GAS CHROMATOGRAPHY; CONTROLLED STUDY; DIET; EXCRETION; GAS LIQUID CHROMATOGRAPHY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN EXPERIMENT; LIPID ABSORPTION; LIPID BLOOD LEVEL; NORMAL HUMAN; PRIORITY JOURNAL; STEROL METABOLISM;

ADOLESCENT; ADULT; CARBON RADIOISOTOPES; CHOLESTEROL; DIET; FEMALE; HALF-LIFE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INTESTINAL ABSORPTION; KINETICS; LIPID METABOLISM, INBORN ERRORS; MALE; MIDDLE AGED; PHYTOSTEROLS; SITOSTEROLS; TRITIUM;

EID: 0033729566     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Metabolism of β-sitosterol in man
2. Absorption and lymphatic transport of cholesterol and sitosterol in the rat
3. Review of cholesterol absorption with emphasis on dietary and biliary cholesterol
4. Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population
5. Evaluation of deuterated cholesterol and deuterated sitostanol for measurement of cholesterol absorption in humans
6. Intestinal absorption and lymphatic transport of cholesterol and β-sitostanol in the rat
7. Comparison and absorption of beta sitosterol and beta sitostanol in rats
8. Effects of sitosterol therapy on plasma lipid and lipoprotein concentrations
9. Plant sterols as cholesterol lowering agents: Clinical trials in patients with hypercholesterolemia and studies of sterol balance
10. β-Sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters
11. Sitosterolemia
12. Increased sitosterol absorption, decreased removal and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis
13. Increased sitosterol absorption is offset by rapid elimination to prevent accumulation in heterozygotes with sitosterolemia
14. Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool of sitosterol in patients with sitosterolemia and xanthomatosis
15. Sitosterol and cholesterol metabolism in a patient with coexisting phytosterolemia and cholestanolosis
16. 7-reductase in liver and mononuclear leukocytes
17. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis
18. The effects of abnormal plasma sterol composition on cellular sterol content and composition and low density lipoprotein uptake and degradation by monocytes and lymphocytes in sitosterolemia with xanthomatosis
19. Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: Diminished mononuclear leukocyte 3-hydroxy-3-methyglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function
20. Sitosterolemia: Exclusion of genes involved in reduced cholesterol biosynthesis
21. Mapping a gene involved in regulating cholesterol absorption: The sitosterolemia locus is found at chromosome 2p21
22. Validation of a dual isotope plasma ratio method for measurement of cholesterol absorption in rats
23. Evaluation of an isotope ratio method for measurement of cholesterol absorption in man
24. Campestanol (24-methyl-5α- cholestan-3β-ol) absorption and distribution in New Zealand White rabbits: Effect of dietary sitostanol
25. 3H]sitosterol
26. Effects of sitosterol and sitostanol on micellar solubility of cholesterol
27. Mechanism of action of plant sterols on inhibition of cholesterol absorption
28. Comparison of cholesterol and β-sitosterol: Effects in jejunal fluid secretion induced by oleate, and absorption from mixed micelle solutions
29. Uptake of 7-dehydro derivatives of cholesterol, campesterol, and β-sitosterol by rat erythrocytes, jejunal villus cells, and brush border membranes
30. Differential absorption of plant sterols in the dog
31. Treatment of severe familial hypercholesterolemia in childhood with sitosterol and sitostanol
32. The effect of beta sitosterol on the serum lipids of young men with arteriosclerotic heart disease
33. Comparison of intestinal absorption of cholesterol with different plant sterols in man