Impaired [Ca2+](i) and pH(i) responses to κ-opioid receptor stimulation in the heart of chronically hypoxic rats

American Journal of Physiology - Cell Physiology

Volumn 279, Issue 5 48-5, 2000, Pages

  Pei, Jian Ming ^a   Zhou, Jing Jun ^a   Bian, Jin Song ^a   Yu, Xiao Chun ^a   Fung, Man Lung ^a   Wong, Tak Ming ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Heart; Hypertrophy; Hypoxia; Intracellular calcium; Intracellular pH; Protein kinase C

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; 5 (N ETHYL N ISOPROPYL)AMILORIDE; CALCIUM ION; CALPHOSTIN C; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; NORBINALTORPHIMINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ACTIVATOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL HYPOXIA; CONTROLLED STUDY; HEART HYPERTROPHY; HEART MUSCLE CELL; MALE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION;

ANIMALIA;

EID: 0033715773     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.279.5.c1483     Document Type: Article

References (62)

1. Calcium transients in feline left ventricular myocytes with hypertrophy induced by slow progressive pressure overload
2. Alterations in calcium handling in cardiac hypertrophy and heart failure
3. Mechanisms of transmembrane calcium movement in cultured chick embryo ventricular cells
4. Altered calcium handling in left ventricular pressure-overload hypertrophy as detected with aequorin in the isolated, perfused ferret heart
5. Effects of κ-opioid receptor stimulation in the heart and the involvement of protein kinase C
6. -
7. Signal transduction mechanisms controlling cardiac contractility and their alterations in chronic heart failure
8. Cardiac beta-adrenergic receptor function in fetal sheep exposed to long-term high-altitude hypoxemia
9. Changes in myoplasmic pH and calcium concentration during exposure to lactate in the isolated rat ventricular myocytes
10. Prodynorphin mRNA expression in adult cultured rat ventricular cardiac myocytes
11. 2+ in adult rat cardiac myocytes
12. 2+ homeostasis of cardiac myocytes
13. Cell geometry and contractile abnormalities of myocytes from failing human left ventricle
14. Calcium antagonistic antiarrhythmic actions of CPU-23, a substituted tetrahydroisopuinoline
15. + exchange gene in the rat heart
16. Altered calcium handling in experimental pressure-overload hypertrophy in the ferret
17. Sarcoplasmic reticulum calcium mobilization in right ventricular pressure-overload hypertrophy in the ferret: Relationships to diastolic dysfunction and a negative treppe
18. Early changes in the functions of cardiac sarcoplasmic reticulum in volume-overloaded cardiac hypertrophy in rats
19. + exchange is impaired in cardiac hypertrophy
20. Alpha-adrenergic regulation of phosphoinositide metabolism and protein kinase C in isolated cardiac myocytes
21. + exchange in cardiac physiology and pathophysiology: Mediation of myocardial reperfusion injury by the pH paradox
22. Effect of U- 50,488H on the contractile response of cardiomyopathic hamster ventricular myocytes
23. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C
24. Control of steady-state intracellular pH in intact perfused ferret hearts
25. Opiate binding in rat hearts: Modulation of binding after hemorrhagic shock
26. - exchange
27. Effects of 5-day hypoxia on cardiac adrenergic neurotransmission in rats
28. 5]enkephalin
29. Pathophysiology of cardiac hypertrophy and failure of human working myocardium: Abnormalities in calcium handling
30. 2+](i) during acidosis in cardiac cells
31. Effect of hypertrophy on mechanisms of relaxation in isolated cardiac myocytes from guinea pig
32. Ventilatory and haemopoietic responses to chronic hypoxia in two rat strains
33. Acidosis antagonizes intracellular calcium response to κ-opioid receptor stimulation in the rat heart
34. Impaired G(s)α and adenylyl cyclase cause β-adrenoceptor desensitization in chronically hypoxic rat hearts
35. Amiloride analogs inhibit chronic hypoxic pulmonary hypertension
36. 2+ accumulation in cardiac sarcoplasmic reticulum
37. Protein kinase C isoform expression in normal and failing rabbit hearts
38. Influence of pH(i) and creatine phosphate on alpha-adrenoceptor-mediated cardiac hypertrophy
39. Parathyroid hormone induces protein kinase C but not adenylate cyclase in adult cardiomyocytes and regulates cyclic AMP levels via protein kinase C-dependent phosphodiesterase activity
40. Lithium attenuates the effects of dynorphin (A1-13) on inositol (1,4,5)trisphosphate and intracellular calcium in rat ventricular myocytes
41. 2+](i) in myocytes
42. 2+ elevation evoked by κ-opioid receptor in rat myocytes
43. A cellular mechanism for impaired posthypoxic relaxation in isolated cardiac myocytes. Altered myofilament relaxation kinetics at reoxygenation
44. 2+] in single cardiac cells with fura-2 or indo-1
45. Depressed intracellular calcium transients and contraction in myocytes from hypertrophied and failing guinea pig hearts
46. Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays
47. + antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system
48. 3H]U69593 binding sites in the rat heart by receptor binding assays
49. Growth factors mediate intracellular signaling in vascular smooth muscle cells through protein kinase C-linked pathways
50. Opioid receptors in rat cardiac sarcolemma: Effect of phenylephrine and isoproterenol
51. 2+ in cardiac myocytes
52. Dynorphin gene expression and release in the myocardial cell
53. Opioid peptide gene expression in the primary hereditary cardiomyopathy of the Syrian hamster. III. Autocrine stimulation of prodynorphin gene expression by dynorphin B
54. 2+ release from an intracellular pool in myocytes and neurons
55. Effects of hypoxia on density of beta-adrenergic receptors
56. Proenkephalin- and prodynorphin-derived peptides in guinea-heart
57. Tissue distribution of opioid receptor gene expression in the rat
58. Characterization of a stimulatory adenosine A2a receptor in adult rat ventricular myocyte
59. U50,488H inhibits effects of norepinephrine in rat cardiomyocytes-cross talk between κ-opioid and β-adrenergic receptors
60. Multiplicity of kappa opioid receptor binding in the rat cardiac sarcolemma
61. 2+ pathway in the cardiac κ-opioid receptor
62. 3H]U69593 binding and the cardiac effects of U50,488H by calcium channel blockers in the rat heart