Facilitation of the L-type calcium current in rabbit sino-atrial cells: Effect on cardiac automaticity

Cardiovascular Research

Volumn 48, Issue 3, 2000, Pages 375-392

  Du, Xiao Jun ^a   Gao, Xiao Ming ^a   Wang, Binghui ^a   Jennings, Garry L ^a   Woodcock, Elizabeth A ^a   Dart, Anthony M ^a  

^a ALFRED HOSPITAL   (Australia)

Author keywords

Ca channel; Impulse formation; Sinus node

Indexed keywords

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; ELECTRIC POTENTIAL; FACILITATION; FREQUENCY ANALYSIS; HEART AUTOMATICITY; HEART DEPOLARIZATION; HEART RATE VARIABILITY; MEMBRANE POTENTIAL; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; RABBIT; REGULATORY MECHANISM; SINUS NODE;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; COMPUTER SIMULATION; ELECTRIC STIMULATION; EXTRACELLULAR SPACE; FEEDBACK; MEMBRANE POTENTIALS; MODELS, CARDIOVASCULAR; MYOCARDIAL CONTRACTION; PATCH-CLAMP TECHNIQUES; RABBITS; SINOATRIAL NODE;

EID: 0033711754     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00182-6     Document Type: Article

References (52)

1. Electrophysiology of the sinoatrial node
2. A model of cardiac electrical activity incorporating ionic pumps and concentration changes
3. A mathematical model of a rabbit sinoatrial node cell
4. Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells
5. Ionic mechanisms of the cardiac pacemaker potential
6. Voltage-clamp investigations of membrane currents underlying pace-maker activity in rabbit sino-atrial node
7. Regulation of cardiac ion channels by catecholamines, acetylcholine and second messengers systems
8. Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells
9. A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells
10. Pacemaker mechanisms in in cardiac tissue
11. 2+ currents in compensated heart failure
12. Cardiac pacemaking in the sinoatrial node
13. Muscarinic control of the hyperpolarization-activated current (i(f)) in rabbit sino-atrial node myocytes
14. A G protein directly regulates mammalian calcium channels
15. The calcium and frequency dependence of the slow inward current 'staircase' in frog atrium
16. Influence of a change in stimulation rate on action potentials, currents and contractions in rat ventricular cells
17. Calcium current restitution in mammalian ventricular myocytes is modulated by intracellular calcium
18. Potentiation of the calcium-channel currents of internally perfused mammalian heart cells by repetitive depolarizations
19. 2+ currents in guinea pig myocytes
20. 2+ channel gating differentially modulated by physiological stimuli
21. Interconversion between distinct gating pathways of the high threshold calcium channel in rat ventricular myocytes
22. High frequency-induced upregulation of human cardiac calcium currents
23. 2+ channel activity: Mechanism and implication in force-frequency relation
24. Facilitation of L-type calcium currents by diastolic depolarization in cardiac cells: Impairment in heart failure
25. Properties of the hyperpolarisation-activated (I(f)) in cells isolated from the rabbit sino-atrial node
26. Inhibition of the hyperpolarization activated current (I(f)) induced by acetylcholine in rabbit sino-atrial node myocytes
27. Calcium tolerant ventricular myocytes prepared by preincubation in a 'KB medium'
28. Improved patch-clamp techniques for high-resolution current recording from cells and cell free membrane patches
29. Ionic mechanisms in normal and abnormal cardiac pacemaker activity
30. Regional differences in effects of 4-aminoppyridine within the sinoatrial node
31. Removal of syalic acid alters both T- and L-type calcium currents in cardiac myocytes
32. + current in rabbit sino-atrial node pacemaker cells
33. Inactivation of calcium channels in mammalian heart cells: Joint dependence on membrane potential and intracellular calcium
34. Ca channels in cardiac myocytes: Structure and function in Ca influx and intracellular Ca release
35. Regulation of the frequency-dependent facilitation of L-type calcium currents in rat ventricular cells
36. 2+ channels and ryanodine receptors in rat ventricular myocytes
37. Mechanisms of inactivation of L-type calcium channels in human atrial myocytes
38. 2+ signalling
39. 2+ channels in mouse ventricular myocytes
40. 2+ release by the sarcoplasmic reticulum
41. The voltage-sensitive release mechanism: A new trigger for cardiac contraction
42. Ionic current mechanisms generating vertebrate primary cardiac pacemaker activity at the single cell level: An integrative view
43. 2+ current to electrical activity in sinoatrial nodal myocytes of rabbits
44. Calcium currents
45. Ionic currents during sustained pacemaker activity in rabbit sino-atrial myocytes
46. 2+ and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node
47. Sinus bradycardia, sinus arrest, and sinoatrial exit block: Pathophysiological, electocardiographic, and clinical considerations
48. Voltage clamp investigations of membrane current underlying pacemaker activity in rabbit sino-atrial node
49. 2+ of the hyperpolarization-activated inward current in rabbit single sino-atrial node cells
50. Intracellular calcium does not directly modulate cardiac pacemaker I(f) channels