Meiotic nondisjunction of chromosomes 1, 17, 18, X, and Y in men more than 80 years of age

Biology of Reproduction

Volumn 63, Issue 6, 2000, Pages 1727-1729

  Guttenbach, M ^a   Kohn, F M ^a   Engel, W ^a   Schmid, M ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Aging; Meiosis; Sperm

Indexed keywords

AGED; AGING; ARTICLE; CHROMOSOME 1; CHROMOSOME 17; CHROMOSOME 18; DIPLOIDY; DISOMY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; MALE; MEIOSIS; PATERNAL AGE; PRIORITY JOURNAL; SPERMATOZOON; SPERMATOZOON COUNT; X CHROMOSOME; Y CHROMOSOME;

EID: 0033708759     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod63.6.1727     Document Type: Article

References (19)

1. Chromosomal abnormalities in human reproductive wastage
2. On the parental origin of de novo mutation in man
3. Origin and mechanisms of non-disjunction in human autosomal trisomies
4. Paternal age and Down's syndrome genotypes diagnosed prenatally: No association in New York State data
5. Factual, statistical and logical issues in the search for a paternal age effect for Down syndrome
6. Controversy concerning paternal age effect in 47,+21 Down's syndrome
7. Reduced recombination and paternal age effect in Klinefelter syndrome
8. The incidence, origin, and etiology of aneuploidy
9. The relationship between paternal age, sex ratios, and aneuploidy frequencies in human sperm, as assessed by multicolor FISH
10. Non-disjunction in human sperm: Evidence for an effect of increasing paternal age
11. Paternal age effect of YY aneuploidy in human sperm, as assessed by fluorescence in situ hybridization
12. Donor age and the frequency of disomy for chromosomes 1, 13, 21 and structural abnormalities in human spermatozoa using multicolour in-situ hybridization
13. Disomy rates for chromosomes 14 and 21 studied by fluorescent insitu hybridization in spermatozoa from three men over 60 years of age
14. Cloning of satellite III DNA: Different components are on different chromosomes
15. Segregation of sex chromosomes into sperm nuclei in a man with 47,XXY Klinefelter's syndrome: A FISH analysis
16. The effect of age on the frequency of sperm chromosomal abnormalities in normal men
17. Estimation of aneuploidy levels in human spermatozoa using chromosome specific probes and in situ hybridization
18. Analysis of structural and numerical chromosome abnormalities in sperm of normal men and carriers of constitutional chromosome aberrations. A review
19. Detection of chromosomes and estimation of aneuploidy in human spermatozoa using fluorescence in-situ hybridization