Disomy rates for chromosomes 14 and 21 studied by fluorescent in-situ hybridization in spermatozoa from three men over 60 years of age

Molecular Human Reproduction

Volumn 4, Issue 7, 1998, Pages 695-699

  Rousseaux, Sophie ^a   Hazzouri, Mira ^a   Pelletier, Roberte ^a   Monteil, Michèle ^a   Usson, Yves ^a   Sèle, Bernard ^a  

^a INSERM   (France)

Author keywords

Aneuploid; Fluorescence in situ hybridization; Paternal age; Spermatozoa; Trisomy 21

Indexed keywords

ADULT; AGE; ARTICLE; CHROMOSOME 14; CHROMOSOME 21; CHROMOSOME ANALYSIS; DISOMY; DNA DETERMINATION; DNA PROBE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; SPERM; YEAST ARTIFICIAL CHROMOSOME;

ADULT; AGED; CHROMOSOMES, ARTIFICIAL, YEAST; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 21; DIPLOIDY; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; NONDISJUNCTION, GENETIC; PATERNAL AGE; SPERMATOZOA;

EID: 0031826302     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/4.7.695     Document Type: Article

References (36)

1. Bischoff, F.Z., Nguyen, D.D., Burt, K J. and Shaffer, L.G. (1994) Estimates of aneuploidy using multicolor fluorescence in situ hybridization on human sperm. Cytogenet. Cell Genet , 66, 237-243. [Published erratum appears in Cytogenet. Cell. Genet., 1995; 69, 189].
2. Blanco, J., Egozcue, J. and Vidal, F. (1996) Incidence of chromosome 21 disomy in human spermatozoa as determined by fluorescent in-situ hybridization [see comments]. Hum. Reprod., 11, 722-726.
3. Cross, P.K. and Hook, E.B. (1987) An analysis of paternal age and 47,+21 in 35,000 new prenatal cytogenetic diagnosis data from the New York State Chromosome Registry: no significant effect. Hum. Genet., 77, 307-316.
4. Eichenlaub-Ritter, U. (1996) Parental age-related aneuploidy in human germ cells and offspring: a story of past and present. Environ. Mol. Mutagen., 28, 211-236.
5. Griffin, D.K., Abruzzo, M.A., Millie, E.A. et al. (1995) Non-disjunction in human sperm: evidence for an effect of increasing paternal age. Hum. Mol. Genet., 4, 2227-2232.
6. Guttenbach, M., Martinez-Exposito, M.J., Michelmann, H.W. et al. (1997a) Incidence of diploid and disomic sperm nuclei in 45 infertile men. Hum. Reprod., 12, 468-473.
7. Guttenbach, M., Engel, W. and Schmid, M. (1997b) Analysis of structural and numerical chromosome abnormalities in sperm of normal men and carriers of constitutional chromosome aberrations. A review. Hum. Genet., 100, 1-21.
8. Hassold, T., Abruzzo, M., Adkins, K. et al. (1996) Human aneuploidy: incidence, origin, and etiology. Environ. Mol Mutagen., 28, 167-175.
9. Hassold, T.J. (1998) Nondisjunction in the human male. Curr. Top. Dev. Biol., 37, 383-406.
10. Hook, E.B. (1987) Issues in analysis of data on paternal age and 47,+21: implications for genetic counseling for Down syndrome [see comments]. Hum. Genet., 77, 303-306.
11. Kinakin, B., Rademaker, A., & Martin, R. (1997) Paternal age effect of YY aneuploidy in human sperm, as assessed by fluorescence in situ hybridization. Cytogenet. Cell. Genet., 78, 116-119.
12. Lengauer, C., Green, E.D. and Cremer, T. (1992) Fluorescence in situ hybridization of YAC clones after alu-PCR amplification. Genomics, 13, 826-828.
13. Lorda-Sanchez, I., Binkert, F., Maechler, M. et al. (1992a) Reduced recombination and paternal age effect in Klinefelter syndrome. Hum. Genet., 89, 524-530.
14. Lorda-Sanchez, I., Binkert, F., Maechler, M. and Schinzel, A. (1992b) Molecular study of 45,X conceptuses: correlation with clinical findings. Am. J. Med Genet., 42, 487-490.
15. Lowe, X., Collins, B., Allen, J. et al. (1995) Aneuploidies and micronuclei in the germ cells of male mice of advanced age. Mutat. Res., 338, 59-76.
16. MacDonald, M., Hassold, T., Harvey, J. et al. (1994) The origin of 47,XXY and 47,XXX aneuploidy: heterogeneous mechanisms and role of aberrant recombination. Hum. Mol. Genet., 3, 1365-1371.
17. Martin, R.H., Spriggs, E., Ko, E. and Rademaker, A.W. (1995a) The relationship between paternal age, sex ratios, and aneuploidy frequencies in human sperm, as assessed by multicolor FISH. Am. J. Hum. Genet., 57, 1395-1399.
18. Martin, R.H. and Rademaker, A. (1995b) Reliability of aneuploidy estimates in human sperm: results of fluorescence in situ hybridization studies using two different scoring criteria. Mol. Reprod. Dev., 42, 89-93.
19. Ogata, T. and Matsuo, N. (1995) Turner syndrome and female sex chromosome aberrations: deduction of the principal factors involved in the development of clinical features. Hum. Genet., 95, 607-629.
20. Petersen, M.B., Antonarakis, S.E., Hassold, TJ. et al. (1993) Paternal nondisjunction in trisomy 21: excess of male patients. Hum. Mol. Genet., 2, 1691-1695.
21. Pinkel, D., Straume, T. and Gray, J.W. (1986a) Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization. Proc. Natl. Acad. Sci. USA, 83, 2934-2938.
22. Pinkel, D., Gray, J.W., Trask, B. et al. (1986b) Cytogenetic analysis by in situ hybridization with fluorescently labeled nucleic acid probes. Cold Spring Harbour Symp Quant Biol., 51, 151-157.
23. Rademaker, A., Spriggs, E., Ko, E. and Martin, R. (1997) Reliability of estimates of diploid human spermatozoa using multicolour fluorescence insitu hybridization. Hum. Reprod., 12, 77-79.
24. Robbins, W.A., Segraves, R., Pinkel, D. and Wyrobek, A.J. (1993) Detection of aneuploid human sperm by fluorescence in situ hybridization: evidence for a donor difference in frequency of sperm disomic for chromosomes 1 and Y. Am. J. Hum. Genet., 52, 799-807.
25. Robbins, W.A., Baulch, J E., Moore, D. et al. (1995) Three-probe fluorescence in situ hybridization to assess chromosome X, Y, and 8 aneuploidy in sperm of 14 men from two healthy groups: evidence for a paternal age effect on sperm aneuploidy. Reprod. Fertil. Dev., 7, 799-809.
26. Rousseaux, S. and Chevret, E. (1995) In-vitro decondensation of human spermatozoa for fluorescence in-situ hybridization. Hum. Reprod., 10, 2209-2213.
27. Rousseaux, S., Chevret, E., Monteil, M. et al (1995) Sperm nuclei analysis of a Robertsonian t(14q21q) carrier, by FISH, using three plasmids and two YAC probes. Hum. Genet., 96, 655-660.
28. Sherman, S.L., Takaesu, N., Freeman, S.B. et al. (1991) Trisomy 21: association between reduced recombination and nondisjunction [see comments]. Am. J. Hum. Genet., 49, 608-620.
29. Spriggs, E.L., Rademaker, A.W. and Martin, R.H. (1996) Aneuploidy in human sperm: the use of multicolor FISH to test various theories of nondisjunction. Am. J. Hum. Genet., 58, 356-362.
30. Stene, J., Stene, E., Stengel-Rutkowski, S. and Murken, I.D. (1981) Paternal age and Down's syndrome: data from prenatal diagnoses (DFG). Hum. Genet., 59, 119-124.
31. Thepot, F., Wack, T., Selva, J., Czyglik, F. and Mayaux, M.J. (1993) [Paternal age and pregnancy issues. The CECOS experience]. Contracept. Fertil. Sex., 21, 388-390.
32. Thepot, F., Mayaux, M.J., Czyglick, F. et al. (1996) Incidence of birth defects after artificial insemination with frozen donor spermatozoa: a collaborative study of the French CECOS Federation on 11 535 pregnancies. Hum. Reprod., 11, 2319-2323.
33. Williams, B.J., Ballenger, C.A., Malter, H.E. et al. (1993) Non-disjunction in human sperm results of fluorescence in situ hybridization studies using two and three probes. Hum. Mol. Genet., 2, 1929-1936.
34. Wyrobek, A J., Robbing, W.A., Mehraein, Y. et al. (1994) Detection of sex chromosomal aneuploidies X-X, Y-Y, and X-Y in human sperm using two-chromosome fluorescence in situ hybridization. Am. J. Med. Genet., 53, 1-7.
35. Wyrobek, A.J., Aardema, M., Eichenlaub-Ritter, U. et al. (1996) Mechanisms and targets involved in maternal and paternal age effects on numerical aneuploidy. Environ. Mol. Mutagen., 28, 254-264.
36. Zaragoza, M.V., Jacobs, P.A., James, R.S. et al. (1994) Nondisjunction of human acrocentric chromosomes: studies of 432 trisomic fetuses and liveborns. Hum. Genet., 94, 411-417.