Nitric oxide: A new player in the modulation of energy metabolism

International Journal of Obesity

Volumn 24, Issue , 2000, Pages S36-S40

  Kapur, S ^a   Picard, F ^a   Perreault, M ^a   Deshaies, Y ^a   Marette, A ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Adipocytes; Endotoxemia; Inflammation; Insulin resistance; Lipopolysaccharide; Nitric oxide synthase isoform; Obesity; Skeletal muscle; Tumor necrosis factor

Indexed keywords

ARGININE; BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; LIPOPROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; BROWN ADIPOSE TISSUE; CONFERENCE PAPER; ENERGY METABOLISM; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HYDROLYSIS; IMMUNITY; INFLAMMATION; LIPID METABOLISM; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; ANIMALS; ENERGY METABOLISM; MUSCLE, SKELETAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OBESITY; RATS;

BACTERIA (MICROORGANISMS);

EID: 0033694103     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0801502     Document Type: Article

References (18)

1. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmac Rev 1991; 43: 109-142.
2. Kapur S, Bedard S, Marcotte B, Cote CH, Marette A. Expression of nitric oxide synthase in skeletal muscle: a novel role for nitric oxide as a modulator of insulin action. Diabetes 1997; 46: 1691-1700.
3. Nathan CF. Secretory products of macrophages. J Clin Invest 1987; 79: 319-326.
4. Andersson J, Nagy S, Bjork L, Abrams J, Holm S, Andersson U. Bacterial toxin-induced cytokine production studied at the single-cell level. Immunol Rev 1992; 127: 69-96.
5. Nathan C. Inducible nitric oxide synthase: what difference does it make? J Clin Invest 1997; 100: 2417-2423.
6. Hardardottir I, Moser AH, Memon R, Grunfeld C, Feingold KR. Effects of TNF, IL-1, and the combination of both cytokines on cholesterol metabolism in Syrian hamsters. Lymphokine Cytokine Res 1994; 13: 161-166.
7. Frayn KN. Hormonal control of metabolism in trauma and sepsis. Clin Endocrinol 1986; 24: 577-599.
8. Westfall MV, Sayeed MM. Basal-and insulin-stimulated muscle glucose transport in endotoxin and bacteremia rats. Am J Physiol 1988; 254: R673-R679.
9. Shangraw RE, Jahoor F, Miyoshi H, Neff WA, Stuart CA, Herndon DN, Wolfe RR. Differentiation between septic and postburn insulin resistance. Metab Clin Exp 1989; 38: 983-989.
10. Wolfe RR. Substrate utilization/insulin resistance in sepsis/trauma. Baillieres Clin Endocrinol Metab 1997; 11: 645-657.
11. Bédard S, Marcotte B, Marette A. Cytokines modulate glucose transport in skeletal muscle by inducing the expression of inducible nitric oxide synthase. Biochem J 1997; 325: 487-493.
12. Spitzer JA, Fish RE. Lipolytic patterns in isolated adipocytes of continuously endotoxemic rats. Circ Shock 1986; 18: 21-29.
13. Gaudiot N, Jaubert AM, Charbonnier E, Sabourault D, Lacasa D, Giudicelli Y, Ribiere C. Modulation of white adipose tissue lipolysis by nitric oxide. J Biol Chem 1998; 273: 13475-13481.
14. Andersson K, Gaudiot N, Ribiere C, Elizalde M, Giudicelli Y, Arner P. A nitric oxide-mediated mechanism regulates lipo-lysis in human adipose tissue in vivo. Br J Pharmac 1999; 126: 1639-1645.
15. Hotamisligil GS, Spiegelman BM. Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes 1994; 43: 1271-1278.
16. Hotamisligil, GS, Arner, P, Caro, JF, Atkinson, RL, Spiegel-man, BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995; 95: 2409-2415.
17. Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 1995; 95: 2111-2119.
18. Saghizadeh M, Ong JM, Garvey WT, Henry RR, and Kern PA. The expression of TNF alpha by human muscle. Relationship to insulin resistance. J Clin Invest 1996; 97: 1111-1116.