c-Fes tyrosine kinase binds to and activates STAT3 after granulocyte-macrophage colony-stimulating factor stimulation

Cancer Letters

Volumn 129, Issue 1, 1998, Pages 29-37

  Park, Woong Yang ^a   Ahn, Jung Hyuck ^a   Feldman, Ricardo A ^b,c   Seo, Jeong Sun ^a  

^a Seoul National University College of Medicine   (South Korea)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

c Fes; GM CSF; Interaction; STAT; Tyrosine phosphorylation

Indexed keywords

DNA; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; MUTANT PROTEIN; PROTEIN TYROSINE KINASE; STAT3 PROTEIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

BASE SEQUENCE; DNA; DNA-BINDING PROTEINS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

EID: 0032479519     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00077-9     Document Type: Article

References (39)

1. Metcalf D. Control of granulocytes and macrophages: molecular, cellular, and clinical aspects. Science. 254:1991;529.
2. Cosman D., Lyman S.D., Idzerda R.L., Beckman M.P., Park L.S., Goodwin R.G., March C.J. A new cytokine receptor superfamily. Trends Biochem. Sci. 15:1990;265.
3. Kitamura T., Sato N., Arai K., Miyajima A. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell. 66:1991;1165.
4. Hayashida K., Kitamura T., Gorman D.M., Arai K., Yokota T., Miyajima A. Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc. Natl. Acad. Sci. USA. 87:1990;9655.
5. Tavernier J., Devos R., Cornelis S., Tuypens T., Van der Heyden J., Fiers W., Plaetinck G. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF. Cell. 66:1991;1175.
6. Witthuhn B.A., Quelle F.W., Silvennoinen O., Yi T., Tang B., Miura O., Ihle J.N. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell. 74:1993;227.
7. Silvennoinen O., Schindler C., Schlessinger J., Levy D.E. Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation. Science. 261:1993;1736.
8. Corey S., Eguinoa A., Puyana-Theall K., Bolen J.B., Cantley L., Mollinedo F., Jackson T.R., Hawkins P.T., Stephens L.R. Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src-related tyrosine kinase(s) in human myeloid derived cells. EMBO J. 12:1993;2681.
9. Linnekin D., Howard O.M., Park L., Farrar W., Ferris D., Longo D.L. Hck expression correlates with granulocyte-macrophage colony-stimulating factor-induced proliferation in HL-60 cells. Blood. 84:1994;94.
10. Smithgall T.E., Yu G., Glazer R.I. Identification of the differentiation-associated p93 tyrosine protein kinase of HL-60 leukemia cells as the product of the human c-fes locus and its expression in myelomonocytic cells. J. Biol. Chem. 263:1988;15050.
11. Jucker M., Feldman R.A. Identification of a new adapter protein that may link the common β subunit of the receptor for granulocyte/macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 to phosphatidylinositol 3-kinase. J. Biol. Chem. 270:1995;27817.
12. Hanazono Y., Chiba S., Sasaki K., Mano H., Miyajima A., Arai K., Yazaki Y., Hirai H. c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3. EMBO J. 12:1993;1641.
13. Feldman R.A., Gabrilove J.L., Tam J.P., Moore M.A.S., Hanafusa H. Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells. Proc. Natl. Acad. Sci. USA. 82:1985;2379.
14. MacDonald I., Levy J., Pawson T. Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related protein. Mol. Cell. Biol. 5:1985;2543.
15. Samarut J., Mathey-Prevot B., Hanafusa H. Preferential expression of the c-fps protein in chicken macrophages and granulocytic cells. Mol. Cell. Biol. 5:1985;1067.
16. Care A., Mattia G., Montesoro E., Parolini I., Russo G., Colombo M.P., Peschle C. c-fes expression in ontogenetic development and hematopoietic differentiation. Oncogene. 9:1994;739.
17. Darnell J.E., Kerr I.M., Stark G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 264:1994;1415.
18. Ihle J.N. STATs: signal transducers and activators of transcription. Cell. 84:1996;331.
19. Stahl N.T., Farruggella J., Boulton T.G., Zhong Z., Darnell J.E., Yancopoulos G.D. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science. 267:1995;1349.
20. Migone T.S., Lin J.-X., Ceresto A., Mulloy J.C., O'Shea J.J., Franchini G., Leonard W.J. Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I. Science. 269:1995;79.
21. Yu C.-L., Meyer D.J., Campbell G.S., Larner A.C., Carter-Su C., Schwartz J., Jove R. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science. 269:1995;81.
22. Danial N.N., Pernis A., Rothman P.B. Jak-STAT signaling induced by the v-abl oncogene. Science. 269:1995;1875.
23. David M., Petricoin E., Benjamin C., Pine R., Weber M.J., Larner A.C. Requirement for MAP kinase (ERK2) activity in interferon alpha and interferon beta-stimulated gene expression through STAT proteins. Science. 269:1995;1721.
24. Dignam J.D., Lebovitz R.M., Roeder R.G. Accurate transcription initiation by RNA polmerase II in soluble extracts from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475.
25. Feldman R.A., Lowy D.R., Vass W.C., Velu T.J. A highly efficient retroviral vector allows detection of the transforming activity of the human c-fps/fes proto-oncogene. J. Virol. 63:1989;5469.
26. Kunkel T.A. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA. 82:1985;488.
27. Wagner B.J., Hayes T.E., Hoban C.J., Cochran B.H. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J. 9:1990;4477.
28. Quelle F., Sato N., Witthuhn B.A., Inhorn R.C., Eder M., Miyajima A., Griffin J.D., Ihle J.N. JAK2 associates with the common beta chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol. Cell. Biol. 14:1994;4335.
29. Brizzi M.F., Aronica M.G., Rosso A., Bangnara G.P., Yarden Y., Pegoraro L. Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signalling pathway and rapidly activates p93fes, STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytes. J. Biol. Chem. 271:1996;3562.
30. Greer P., Haigh J., Mbamalu G., Khoo W., Bernstein A., Pawson T. The Fps/Fes protein-tyrosine kinase promotes angiogenesis in transgenic mice. Mol. Cell. Biol. 14:1994;6755.
31. Yu G., Smithgall T.E., Glazer R.I. K562 leukemia cells transfected with the human c-fes gene acquire the ability to undergo myeloid differentiation. J. Biol. Chem. 264:1989;10276.
32. Koeffler H.P., Billing R., Lusis A.J., Sparkes R., Golde D.W. An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1). Blood. 56:1980;265.
33. Manfredini R., Grande A., Tagliafico E., Barbieri D., Zucchini P., Citro G., Zupi G., Franceschi C., Torelli U., Ferrari S. Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation. J. Exp. Med. 178:1993;381.
34. Nagata Y., Todokoro K. Interleukin-3 activates not only JAK2 and STAT5, but also Tyk2, STAT1, and STAT3. Biochem. Biophys. Res. Commun. 221:1996;785.
35. Caldenhoven E., van Dijk T., Raaijmakers J.A., Lammers J.M., Koenderman L., De Groot R.P. Activation of the STAT3/acute phase response factor transcription factor by interleukin-5. J. Biol. Chem. 270:1995;25778.
36. Rosen R.L., Winestock K.D., Chen G., Liu X., Hennighausen L., Finbloom D.S. Granulocyte-macrophage colony-stimulating factor preferentially activates the 94-kDa STAT5A and an 80kDa STAT5B isoform in human peripheral blood monocytes. Blood. 88:1996;1206.
37. Mui A.L., Wakao H., O'Farell A.-M., Miyajima A. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J. 14:1996;1166.
38. Cao X., Tay A., Guy G., Tan Y.H. Activation and association of Stat3 with Src in v-Src-transformed cell line. Mol. Cell. Biol. 16:1996;1595.
39. gag-fps. Biochem. Biophys. Res. Commun. 211:1995;447.