Multi-site DNA polymorphism analyses of Leishmania isolates define their genotypes predicting clinical epidemiology of Leishmaniasis in a specific region

Journal of Eukaryotic Microbiology

Volumn 47, Issue 6, 2000, Pages 545-554

  Akman, Leyla ^a   Aksu, H S Z ^b   Wang, R Q ^a   Ozensoy, S ^b   Ozbel, Y ^b   Alkan, Z ^b   Ozcel, M A ^b   Culha, G ^b   Ozcan, K ^b   Uzun, S ^c   Memisoglu, H R ^c   Chang, Kwang Poo ^a  

^a University of the Health Sciences   (United States)

^b CUKUROVA UNIVERSITY   (Turkey)

^c EGE UNIVERSITY   (Turkey)

Author keywords

Clinical epidemiology; Kinetoplast DNA; Leishmania; N acetylglucosamine l transferase; Nuclear DNA; Phylogeny; Sequence polymorphism

Indexed keywords

DNA POLYMORPHISM; GENETIC HETEROGENEITY; GENOTYPE; GEOGRAPHIC DISTRIBUTION; LEISHMANIASIS; N ACETYLGLUCOSAMINE 1 PHOSPHATE TRANSFERASE; PHYLOGENY; SEQUENCE ALIGNMENT; TURKEY;

LEISHMANIA; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LEISHMANIA TROPICA;

EID: 0033670005     PISSN: 10665234     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1550-7408.2000.tb00088.x     Document Type: Article

References (52)

1. The GAP project in southeastern Turkey: The potential for emergence of diseases
2. Sand flies (Diptera: Psychodidae) associated with epidemic cutaneous leishmaniasis in Sanliurfa, Turkey
3. Biochemical identification of cutaneous leishmanias by analysis of kinetoplast DNA. II. Sequence homologies in Leishmania kDNA
4. Molecular approaches to DNA diagnosis
5. Evolution of the genus Leishmania as revealed by comparisons of nuclear DNA restriction fragment patterns
6. Characterization of Leishmania donovani stocks by genomic DNA heterogeneity and molecular karyotype
7. Phylogenetic taxonomy of Leishmania (Viannia) braziliensis based on isoenzymatic Study of 137 isolates
8. Evolution of the genus Leishmania revealed by comparison of DNA and RNA polymerase gene sequences
9. A general classification of New World Leishmania using numerical zymotaxonomy
10. Discrimination of Leishmania isolates using a limited set of enzymatic loci
11. Intergenic region typing (IRT): A rapid molecular approach to the characterization and evolution of Leishmania
12. A comparative study of diagnosis by the polymerase chain reaction and by current clinical methods using biopsies from Colombian patients with suspected leishmaniasis
13. Leishmania major: Effect of infectious dose on T cell subset development in BALB/c mice
14. PHYLIP - Phylogeny Inference Package (Version 3. 2)
15. Evolution of nuclear ribosomal RNAs in kinetoplastid protozoa: Perspectives on the age and origins of parasitism
16. 18S rRNA sequences of Leishmania enriettii promastigote and amastigote
17. Isoenzyme characterization of Leishmania isolates from human cases of cutaneous leishmaniasis in Urfa, southeast Turkey
18. Phenotypic diversity of cloned lines of Leishmania major promastigotes
19. Species-specific antibodies to Leishmania tropica (minor) recognize somatic antigens and exometabolites
20. Production and characterization of species-specific monoclonal antibodies against Leishmania donovani for immunodiagnosis
21. Stage-independent splicing of transcripts from two heterogeneous neighboring genes in Leishmania amazonensis
22. The causative organism of infantile kalaazar in Egypt
23. Leishmania in the Old World: 5. Numerical analysis of isoenzyme data
24. The 63-kilobase circular amplicon of tunicamycin-resistant Leishmania amazonensis contains a functional N-acetylglucosamine-l-phosphate transferase gene that can be used as a dominant selectable marker in transfection
25. N-acetylglucosamine-l-phosphate transferase gene is conserved in five Leishmania spp. and over-expressed due to its amplification in their tunicamycin-resistant variants
26. Identification of visceral Leishmania species with Cloned sequences of kinetoplast DNA
27. Separation of Chinese Leishmania isolates into five genotypes by kinetoplast and chromosomal DNA heterogeneity
28. The genomic fingerprinting of the coding region of the β-tubulin gene in Leishmania identification
29. Posttranslational regulation of a Leishmania HEXXH metalloprotease (gp63). The effects of site-specific mutagenesis of catalytic, zinc binding, N-glycosylation, and glycosyl phosphatidylinositol addition sites on N-terminal end cleavage, intracellular stability, and extracellular exit
30. Subspecies - and species - Specific antigens of Leishmania mexicana characterized by monoclonal antibodies
31. The RFLP analysis of the β-tubulin gene region in New World Leishmania
32. Leishmania and Sauroleishmania: The use of random amplified polymorphic DNA for the identification of parasites from vertebrates and invertebrates
33. The Leishmania hertigi (Kinetoplastida; Trypanosomatidae) complex and the lizard Leishmania: Their classification and evidence for a neotropical origin of the Leishmania - Endotrypanum clade
34. Epidemiology, diagnosis and control of leishmaniasis in the Mediterranean region
35. Serodiagnosis and epidemiology of visceral leishmaniasis in Turkey
36. TreeView: An application to display phylogenetic trees on personal computers
37. Identification of intra- and inter-specific Leishmania genetic polymorphisms by arbitrary primed polymerase chain reactions and use of polymorphic DNA to identify differentially regulated genes
38. Conservation of low-copy gene loci in Old World leishmanias identifies mechanisms of parasite evolution and diagnostic markers
39. Amplification of kinetoplast DNA as a tool in the detection and diagnosis of Leishmania
40. Kinetoplast DNA minicircles: Regions of extensive sequence divergence
41. Is Leishmania major the cause of infantile kala-azar in Alexandria, Egypt?
42. The mitochondrial genome of kinetoplastid protozoa: Genomic organization, transcription, replication, and evolution
43. The use of heparin as a simple cost-effective means of controlling background in nucleic acid hybridization procedures
44. Kinetoplast DNA, mitochondrial DNA with a difference
45. A clonal theory of parasitic protozoa: The population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences
46. Genetic characterization of six parasitic protozoa: Parity between random-primer DNA typing and multilocus enzyme electrophoresis
47. A nuclear DNA probe for the identification of strains within the Leishmania donovani complex
48. The gp63 gene locus, a target for genetic characterization of Leishmania belonging to subgenus Viannia
49. Comparative study of the ribosomal RNA from Leishmania and Trypanosoma
50. Rapid identification of Leishmania species by specific hybridization of kinetoplast DNA in cutaneous lesions