Administration of adenosine during reperfusion reduces injury of vascular endothelium and death of myocytes

Coronary Artery Disease

Volumn 10, Issue 8, 1999, Pages 617-628

  Zhao, Zhi Qing ^a   Nakamura, Masanori ^a   Wang, Ning Ping ^a   Wilcox, Josiah N ^a   Shearer, Steven ^a   Guyton, Robert A ^a   Vinten Johansen, Jakob ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine; Apoptosis; Infarct size; Neutrophils; Reperfusion injury

Indexed keywords

ACETYLCHOLINE; ADENOSINE; CD18 ANTIGEN; CREATINE KINASE; DNA NUCLEOTIDYLEXOTRANSFERASE; DRUG VEHICLE; HEART ENZYME; MICROSPHERE; MONOCLONAL ANTIBODY; MYELOPEROXIDASE; SODIUM CHLORIDE; SUPEROXIDE; TRIPHENYLTETRAZOLIUM; URIDINE TRIPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DOG; DOSE RESPONSE; ENZYME ACTIVITY; FEMALE; GEL ELECTROPHORESIS; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT ATRIUM; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; VASCULAR ENDOTHELIUM;

EID: 0032762058     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-199912000-00011     Document Type: Article

References (47)

1. 1 Hearse DJ, Bolli R. Reperfusion induced injury: manifestations, mechanisms, and clinical relevance [review]. Cardiovasc Res 1992; 26:101-108.
2. 2 Mehta JL, Nichols WW, Mehta P. Neutrophils as potential participants in acute myocardial ischemia: relevance to reperfusion. J Am Coll Cardiol 1988; 11:1309-1316.
3. 3 Dreyer WJ, Michael LH, West MW, Smith CW, Rothlein R, Rossen RD, et al. Neutrophil accumulation in ischemic canine myocardium: insights into time course, distribution, and mechanism of localization during early reperfusion. Circulation 1991; 84:400-411.
4. 4 Nakanishi K, Vinten-Johansen J, Lefer DJ, Zhao Z, Fowler WC III, McGee DJ, et al. Intracoronary L-arginine during reperfusion improves endothelial function and reduces infarct size. Am J Physiol 1992; 263:H1650-H1658.
5. 5 Entman ML, Michael L, Rossen RD, Dreyer WJ, Anderson DC, Taylor AA, et al. Inflammation in the course of early myocardial ischemia. FASEB J 1991; 5:2529-2537.
6. 6 Jolly SR, Kane WJ, Bailie MB, Abrams GD, Lucchesi BR. Canine myocardial reperfusion injury: its reduction by the combined administration of superoxide dismutase and catalase. Circ Res 1984; 54:277-285.
7. 7 Ma X-L, Tsao PS, Lefer AM. Antibody to CD-18 exerts endothelial and cardiac protective effects in myocardial ischemia and reperfusion. J Clin Invest 1991; 88:1237-1243.
8. 8 Engler RL, Dahlgren MD, Morris D, Peterson MA, Schmid-Schönbein GW. Role of leukocytes in response to acute myocardial ischemia and reflow in dogs. Am J Physiol 1986; 251:H314-H322.
9. 9 Cotran RS, Kumar V, Robbins SL, Schoen FJ. Cellular injury and cellular death. In: Cotran RS, Kumar V, Robbins SL, Schoen FJ (editors): Pathologic basis of disease. Philadelphia: W.B. Saunders Company; 1994. pp. 1-33.
10. 10 Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 1994; 94:1621-1628.
11. 11 MacLellan WR, Schneider MD. Death by design. Programmed cell death in cardiovascular biology and disease. Circ Res 1997; 81:137-144.
12. 12 Saraste A, Pulkki K, Kallajoki M, Henriksen K, Parvinen M, Voipio-Pulkki L-M. Apoptosis in human acute myocardial infarction. Circulation 1997; 95:320-323.
13. 13 Fliss H, Gattinger D, Apoptosis in ischemic and reperfused rat myocardium. Circ Res 1996; 79:949-956.
14. 14 Piot CA, Padmanaban D, Ursell PC, Sievera RE, Wolfe CL. Ischemic preconditioning decreases apoptosis in rat hearts in vivo. Circulation 1997; 96:1598-1604.
15. 15 Vakeva AP, Agah A, Rollins SA, Matis LA, Li L, Stahl GL. Myocardial infarction and apoptosis after myocardial ischemia and reperfusion. Role of the terminal complement components and inhibition by anti-C5 therapy. Circulation 1998; 97:2259-2267.
16. 16 Yue T-L, Ma X-L, Wang X, Romanic AM, Liu G-I, Louden C, et al. Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol. Circ Res 1998; 82:166-174.
17. 17 Yang JJ, Kettritz R, Falk RJ, Jennette JC, Gaido ML. Apoptosis of endothelial cells induced by the neutrophil serine proteases proteinase 3 and elastase. Am J Pathol 1996; 149:1617-1626.
18. 18 Toombs CF, McGee DS, Johnston WE, Vinten-Johansen J. Protection from ischaemic-reperfusion injury with adenosine pretreatment is reversed by inhibition of ATP-sensitive potassium channels. Cardiovasc Res 1993; 27:623-629.
19. 19 Mentzer RM Jr, Bunger R, Lasley RD. Adenosine enhanced preservation of myocardial function and energetics. Possible involvement of the adenosine A1 receptor system. Cardiovasc Res 1993; 27:28-35.
20. 1 selective agonist, 2-chloro-N6-cyclopentyladenosine (CCPA), causes a sustained limitation of infarct size in rabbits. Cardiovas Res 1993; 27:652-656.
21. 1-selective adenosine analogues protects the heart against infarction. Circulation 1992; 85:659-665.
22. 22 Olafsson B, Forman MB, Puett DW, Pou A, Cates CU, Friesinger GC, et al. Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: importance of the endothelium and the no-reflow phenomenon. Circulation 1987; 76:1135-1145.
23. 23 Pitarys CJ, Virmani R, Vildibill HD Jr, Jackson EK, Forman MB. Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period. Circulation 1991; 83:237-247.
24. 24 Verrier ED, Shen I. Potential role of neutrophil anti-adhesion therapy in myocardial stunning, myocardial infarction, and organ dysfunction after cardiopulmonary bypass. J Cardiovasc Surg 1993; 8:309-312.
25. 25 Nichols WW, Nicolini FA, Yang BC, Henson K, Stechmiller JK, Mehta JL. Adenosine protects against attenuation of flow reserve and myocardial function after coronary occlusion and reperfusion. Am Heart J 1994; 127:1201-1211.
26. 2-receptor activation inhibits neutrophil-mediated injury to coronary endothelium. Am J Physiol 1996; 271:H1456-H1464.
27. ATP-channel activation. Am J Physiol 1997; 273:H1677-H1687.
28. 28 Kowallik P, Schulz R, Guth BD, Schade A, Paffhausen W, Gross R, et al. Measurement of regional myocardial blood flow with multiple colored microspheres. Circ Res 1991; 83:974-982.
29. 29 Scott NA, Cipolla GD, Ross CE, Dunn B, Martin FH, Simonet L, et al. Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries. Circulation 1996; 93:2178-2187.
30. 30 Mullane K, Engler R. Proclivity of activated neutrophils to cause postischemic cardiac dysfunction: participation in stunning? Cardiovasc Drugs Ther 1991; 5:915-924.
31. 31 Smith CW, Entman ML, Beaudet AL, Ty TI, Youker K, Hawkins HK, et al. Adherence of neutrophils to canine cardiac myocytes in vitro is dependent on intercellular adhesion molecule-1. J Clin Invest 1991; 88:1216-1223.
32. 32 Albertine KH, Weyrich AS, Ma X-L, Lefer DJ, Becker LC, Lefer AM. Quantification of neutrophil migration following myocardial ischemia and reperfusion in cats and dogs. J Leukocyte Biol. 1994; 55:557-566.
33. 33 Entman ML, Youker K, Shoji T, Kukielka G, Shappell SB, Taylor AA, et al. Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence. J Clin Invest 1992; 90:1335-1345.
34. 34 Smith CW, Entman ML, Lane CL, Beaudet AL, Ty TI, Youker K, et al. Adherence of neutrophils to canine cardiac myocytes in vitro is dependent on intercellular adhesion molecule-1. J Clin Invest 1991; 88:1216-1223.
35. 35 Ma X-L, Lefer DJ, Lefer AM, Rothlein R. Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion. Circulation 1992; 86:937-946.
36. 36 Zhao Z-Q, Lefer DJ, Sato H, Hart KK, Jefforda PR, Vinten-Johansen J. Monoclonal antibody to ICAM-1 preserves postischemic blood flow and reduces infarct size after ischemia-reperfusion in rabbit. J Leukocyte Biol 1997; 62:292-300.
37. 37 Wollner A, Wollner S, Smith JB. Acting via A2 receptors, adenosine inhibits the upregulation of Mac-1 (CD11b/CD18) expression on FMLP-stimulated neutrophils. Am J Resp Cell Mol Biol 1993; 9:179-185.
38. 38 Bolli R, Zughaib M, Li XY, Tang XL, Sun JZ, Triana JF, et al. Recurrent ischemia in the canine heart causes recurrent bursts of free radical production that have a cumulative effect on contractile function. A pathophysiological basis for chronic myocardial 'stunning'. J Clin Invest 1995; 96:1066-1084.
39. 39 Smith EF3, Egan JW, Bugelski PJ, Hillegass LM, Hill DE, Griswold DE. Temporal relation between neutrophil accumulation and myocardial reperfusion injury. Am J Physiol 1988; 255:H1060-H1068.
40. 40 Forman MB, Velasco CE, Jackson EK. Adenosine attenuates reperfusion injury following regional myocardial ischaemia. Cardiovasc Res 1993; 27:9-17.
41. 41 Homeister JW, Hoff PT, Fletcher DD, Lucchesi BR. Combined adenosine and lidocaine administration limits myocardial reperfusion injury. Circulation 1990; 82:595-608.
42. 42 Zhao Z-Q, Nakamura M, Wang N-P, Wilcox JN, Shearer ST, Katzmark S, et al. Reperfusion-induced apoptosis progressively develops in later stages of reflow [abstract]. FASEB J 1999; 13:A816.
43. 43 Ohno M, Takemura G, Ohno A, Misao J, Hayakawa Y, Minatguchi S, et al. 'Apoptotic' myoctyes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation. Analysis by immunogold electron microscopy combined with in situ nick end-labeling. Circulation 1998; 98:1422-1430.
44. 44 Cheng W, Kajstura J, Nitahara JA, Li B, Reiss K, Lui Y, et al. Programmed myocyte cell death affects the viable myocardium after infarction in rats. Exp Cell Res 1996; 226:316-327.
45. 45 Umansky SR, Pisarenko OI, Serebryakova LI, Studeneva IM, Tskitishvili OV, Khutzian SS, et al. Dog cardiomyoctye death induced in vivo by ischemia and reperfusion. BAM 1996; 6:227-235.
46. 46 Freude B, Masters TN, Kostin S, Robicsek F, Schaper J. Cardiomyocyte apoptosis in acute and chronic conditions. Basic Res Cardiol 1998; 93:85-89.
47. 47 Sharov VG, Sabbah HN, Shimoyama H, Goussev AV, Lesch M, Goldstein S. Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure. Am J Pathol 1996; 148:141-149.