16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocytes and reduces intracranial pressure in a rabbit model of thromboembolic stroke

Neurosurgery

Volumn 47, Issue 6, 2000, Pages 1410-1419

  Bednar, Martin M ^a,b   Gross, Cordell E ^a   Russell, Sheila R ^a   Fuller, Susan P ^a   Ahern, Thomas P ^a   Howard, Diantha B ^a   Falck, John R ^c   Reddy, Komandla Malla ^c   Balazy, Michael ^d  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Cerebral ischemia; Hydroxyeicosatetraenoic acid; Intracranial pressure; Leukotriene B4; Polymorphonuclear leukocyte

Indexed keywords

ARACHIDONIC ACID DERIVATIVE; HYDROXYICOSATETRAENOIC ACID; LEUKOTRIENE B4; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL AGGREGATION; CYTOKINE PRODUCTION; INTRACRANIAL HYPERTENSION; ISCHEMIA; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RABBIT; STROKE;

EID: 0033660079     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-200012000-00029     Document Type: Article

References (58)

1. Guidelines for the management of patients with acute ischemic stroke: A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association
2. Comparison of the vasodepressor effects of prostacyclin and 6-oxo-prostaglandin F 1 alpha with those of prostaglandin E2 in rats and rabbits
3. Neutrophil and platelet activity and quantification following delayed t-PA therapy in a rabbit model of thromboembolic stroke
4. Comparison of triphenyltetrazolium dye with light microscopic histopathology in a rabbit model of acute cerebral ischemia
5. 16(R)-HETE, a new arachidonate metabolite in human polymorphonuclear leukocytes
6. Antineutrophil strategies
7. Neutrophil activation in acute human central nervous system injury
8. Nitric oxide reverses aspirin antagonism of t-PA thrombolysis in a rabbit model of thromboembolic stroke
9. Humanized anti-L-selectin monoclonal antibody DREG 200 therapy in acute thromboembolic stroke
10. In vitro evidence supporting two mechanisms of action for the anion transport inhibitor L 644,711 in cerebral ischemia
11. Tissue plasminogen activator reduces brain injury in a rabbit model of thromboembolic stroke
12. Tissue plasminogen activator: Comparison of dose and route of administration in a rabbit model of thromboembolic stroke
13. The role of neutrophils and platelets in a rabbit model of thromboembolic stroke
14. Conversion of arachidonic acid to two novel products by a cytochrome P450-dependent mixed function oxidase in polymorphonuclear leukocytes
15. Nafazatrom-induced salvage of ischemic myocardium in anesthetized dogs is mediated through inhibition of neutrophil function
16. Neutrophil depletion suppresses 111-In-platelet accumulation in infarcted myocardium
17. IB4, a monoclonal antibody against the CD 18 leukocyte adhesion protein, reduces intracranial pressure following thromboembolic stroke in the rabbit
18. The enigma of the decline in stroke deaths in the United States: The search for an explanation
19. One-year outcome after decompressive surgery for massive nondominant hemispheric infarction
20. Anti-CD 11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat
21. Attenuation of postischemic brain hypoperfusion and reperfusion injury by the cyclooxygenaselipoxygenase inhibitor BW 755C
22. Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats
23. Anti-leukocyte adhesion therapy: Preclinical trials and combination therapy
24. Reduction of central nervous system ischemic injury in rabbits using leukocyte adhesion antibody treatment
25. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons
26. Influence of granulocytopenia on canine cerebral ischemia induced by air embolism
27. The enlimomab acute stroke trial: Final results
28. Cytochrome P-450-dependent oxidation of arachidonic acid to 16-, 17-, and 18-hydroxyeicosatetraenoic acids
29. PROACT II: Recombinant prourokinase (rProUK) in acute cerebral thromboembolism
30. Delayed hypoperfusion after incomplete forebrain ischemia in the rat: The role of polymorphonuclear leukocytes
31. Delayed adjuvant therapy with the 21-aminosteroid U74006F and the anion channel blocker L644-711 does not improve outcome following thrombolytic therapy in a rabbit model of thromboembolic stroke
32. Delayed tissue-plasminogen activator therapy in a rabbit model of thromboembolic stroke
33. The omega-hydroxylation of arachidonic acid by human polymorphonuclear leukocytes
34. Modifying the host response to injury: The future of trauma care
35. Quantitation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE) produced by human polymorphonuclear leukocytes using electron capture ionization gas chromatography/mass spectrometry
36. Intravenous prostacyclin in acute nonhemorrhagic stroke: A placebo-controlled double-blind trial
37. Reduction in ischemic brain injury by the anion transport inhibitor L644,711
38. A neutrophil-derived cytochrome P450-dependent metabolite of arachidonic acid modulates neutrophil behavior
39. Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats
40. Role of cell adhesion molecules in brain injury after transient middle cerebral artery occlusion in the rat
41. Circulatory responses to ketamine: Dependence on respiratory pattern and background anaesthesia in the rabbit
42. Adhesion molecules contribute to ischemia and reperfusion-induced injury in the isolated rat lung
43. Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons
44. Randomised control trial of streptokinase, aspirin, and combination of both in treatment of acute ischemic stroke: Multicentre Acute Stroke Trial-Italy (MAST-I) Group
45. Tissue plasminogen activator for acute ischemic stroke
46. CD 18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke
47. Randomized Trial of Tirilazad Mesylate in Acute Stroke (RANTTAS)
48. Stroke in the elderly
49. Identification of time window for therapy to reduce experimental canine myocardial injury: Suppression of neutrophil activation during 72 hours of reperfusion
50. Sustained limitation of myocardial reperfusion injury by a monoclonal antibody that alters leukocyte function
51. The role of leukocyte and endothelial adhesion molecules in ischemia-reperfusion injury
52. Optimized thrombolysis of cerebral clots with tissue-type plasminogen activator in a rabbit model of embolic stroke
53. Intravenous aspirin causes a paradoxical attenuation of cerebrovascular thrombolysis
54. Two-step model of leukocyte-endothelial cell interaction in inflammation: Distinct roles for LECAM- 1 and the leukocyte beta 2 integrins in vivo
55. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood
56. Stimulation of neutrophil adherence to vascular endothelial cells by histamine and thrombin and its inhibition by PAF antagonists and dexamethasone
57. Reduced brain edema after traumatic brain injury in mice deficient in P-selectin and intercellular adhesion molecule-1
58. 2 clearance measurement of blood flow: A 1980 review of technique and polarographic principles