Randomized comparison of mefloquine-artesunate versus quinine in the treatment of multidrug-resistant falciparum malaria in pregnancy

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 94, Issue 6, 2000, Pages 689-693

  McGready, Rose ^a,b,c   Brockman, Alan ^a,b,c   Cho, Thein ^a   Cho, Dju ^a   Van Vugt, Michele ^a,d   Luxemburger, Christine ^a,c   Chongsuphajaisiddhi, Tan ^b   White, Nicholas J ^a,b,c   Nosten, François ^a  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Chemotherapy; Clinical trial; Malaria; Mefloquine artesunate; Plasmodium falciparum; Pregnancy; Quinine; Thailand

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ; ARTEMISININ DERIVATIVE; ARTESUNATE; GLUTAMIC ACID DERIVATIVE; MEFLOQUINE; MEROZOITE SURFACE PROTEIN 1; MEROZOITE SURFACE PROTEIN 2; QUININE SULFATE; SUGAR; WATER;

ADOLESCENT; ADULT; ANOREXIA; ANTIBIOTIC RESISTANCE; ARTHRALGIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE CARRIER; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EARLY DIAGNOSIS; FEMALE; GAMETOCYTE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALARIA CONTROL; MALARIA FALCIPARUM; MULTIDRUG RESISTANCE; MYALGIA; PLASMODIUM FALCIPARUM; PREGNANCY COMPLICATION; PREGNANCY DISORDER; RANDOMIZED CONTROLLED TRIAL; SECOND TRIMESTER PREGNANCY; SIDE EFFECT; STILLBIRTH; THAILAND; THIRD TRIMESTER PREGNANCY; TINNITUS; TREATMENT PLANNING; VERTIGO; VOMITING;

EID: 0033659429     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(00)90235-9     Document Type: Article

References (29)

1. A study of the consequences of malarial infection in pregnant women and their infants
2. Neurotoxicity in animals due to arteether and artemether
3. Application of genetic markers to the identification of recrudescent Plasmodium falciparum infections on the north western border of Thailand
4. Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine
5. Bednets for the prevention of malaria and anaemia in pregnancy
6. Falciparum malaria semi-resistant to clindamycin
7. Clinical trials on qinghaosu and its derivatives
8. Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand
9. The epidemiology of malaria in a Karen population on the Thai-Burmese border
10. Artemisinin derivatives in the treatment of malaria in pregnancy
11. Quinine and mefloquine in the treatment of multidrug resistant Plasmodium falciparum malaria in pregnancy
12. Assessment of the neurotoxicity of parenteral artemisinin derivatives in mice
13. Malaria during pregnancy in an area of unstable endemnicity
14. Treatment of multidrug-resistant Plasmodium falciparum malaria with a 3-day artesunate mefloquine combination
15. The effects of mefloquine treatment in pregnancy
16. Reducing P. falciparum incidence and mefloquine resistance in western Thailand
17. Quinine pharmacokinetics and toxicity in pregnant and lactating women with falciparum malaria
18. Artesunate versus artemether in combination with mefloquine for the treatment of multidrug resistant falciparum malaria
19. Effects of artemisinin derivatives on malaria transmissibility
20. Adverse effects in patients with acute falciparum malaria treated with artemisinin derivatives
21. Factors contributing to anaemia following uncomplicated falciparum malaria
22. Efficacy of six doses of artemether-lumefantrine (benflumetol) in multidrug-resistant Plasmodium falciparum malaria
23. Follow-up observation on the therapeutic effects and remote reactions of artemisinin (qinghaosu) and artemether in treating malaria in pregnant women
24. Antimalarial drug resistance: The pace quickens
25. Preventing antimalarial drug resistance through combinations
26. World Health Organization partograph in management of labour
27. Clinical features of malaria in pregnancy