O6-benzylguanine-mediated enhancement of nitrosourea activity in Mer- central nervous system tumor xenografts - Implications for clinical trials

Cancer Chemotherapy and Pharmacology

Volumn 45, Issue 6, 2000, Pages 437-440

  Keir, Stephen T ^a   Dolan, M Eileen ^b   Pegg, Anthony E ^c   Lawless, Amy ^a   Moschel, Robert C ^d   Bigner, Darell D ^a   Friedman, Henry S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Brain tumors; Glioma; Nitrosourea

Indexed keywords

6 O BENZYLGUANINE; ANTINEOPLASTIC AGENT; CARMUSTINE; DRUG DERIVATIVE; ENZYME INHIBITOR; GUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; O(6) BENZYLGUANINE; O(6)-BENZYLGUANINE;

ANIMAL MODEL; ARTICLE; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER TRANSPLANTATION; CENTRAL NERVOUS SYSTEM TUMOR; CONTROLLED STUDY; ENZYME ACTIVITY; GLIOMA; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CLINICAL TRIAL; FEMALE; GENETICS; MALE; METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS; CARMUSTINE; CENTRAL NERVOUS SYSTEM NEOPLASMS; CLINICAL TRIALS; ENZYME INHIBITORS; FEMALE; GUANINE; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; TRANSPLANTATION, HETEROLOGOUS;

EID: 0033655886     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800051016     Document Type: Article

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