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Volumn 46, Issue 6, 2000, Pages 493-500
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Determination of drug effect on tumour cells, host animal toxicity and drug pharmacokinetics in a hollow-fibre model in rats
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Author keywords
Anticancer drug; CHS 828; In vivo model; NONMEM; Population pharmacokinetics
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Indexed keywords
CYCLOPHOSPHAMIDE;
EPIRUBICIN;
FLUOROURACIL;
GUANIDINE DERIVATIVE;
HEMOGLOBIN;
N (6 CHLOROPHENOXYHEXYL) N' CYANO N'' (4 PYRIDYL)GUANIDINE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
BLOOD TOXICITY;
BREAST CARCINOMA;
CELL DENSITY;
CELL PROLIFERATION;
COMPARTMENT MODEL;
CONTROLLED STUDY;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG CLEARANCE;
DRUG CONCENTRATION;
DRUG EFFECT;
HEMOGLOBIN DETERMINATION;
HUMAN;
HUMAN CELL;
LEUKOCYTE COUNT;
MALE;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
THROMBOCYTE COUNT;
TUMOR CELL CULTURE;
TUMOR CELL LINE;
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EID: 0033653660
PISSN: 03445704
EISSN: None
Source Type: Journal
DOI: 10.1007/s002800000181 Document Type: Article |
Times cited : (31)
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References (23)
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