Pharmacokinetic-pharmacodynamic modelling of the analgesic effect of alfentanil in the rat using tooth pulp evoked potentials

Journal of Pharmacological and Toxicological Methods

Volumn 39, Issue 1, 1998, Pages 19-27

  Cox, Eugène H ^a   Langemeijer, Mariska W E ^a   Danhof, Meindert ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Alfentanil; Analgesia; NONMEM; Pharmacokinetic pharmacodynamic; Tooth pulp evoked potentials

Indexed keywords

ALFENTANIL;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ELECTROENCEPHALOGRAM; EVOKED RESPONSE; INTRAVENOUS DRUG ADMINISTRATION; MALE; MODEL; NONHUMAN; PHARMACODYNAMICS; PHARMACOKINETICS; RAT; TOOTH PAIN; TOOTH PULP;

ALFENTANIL; ANALGESICS, OPIOID; ANIMALS; DENTAL PULP; DRUG EVALUATION, PRECLINICAL; EVOKED POTENTIALS; MALE; PAIN THRESHOLD; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0031946136     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(97)00101-9     Document Type: Article

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