Differential gene expression of hepatocellular carcinoma using cDNA microarray analysis

Oncology Research

Volumn 12, Issue 2, 2000, Pages 59-69

  Lau, Wan Yee ^a   Lai, Paul B S ^a   Leung, Mun Fai ^a   Leung, Billy C S ^a   Wong, Nathalie ^a   Chen, Gong ^a   Leung, Thomas W T ^a   Liew, Choong Tsek ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

cDNA microarray analysis; Gene expression; Hepatocellular carcinoma

Indexed keywords

ACTIN; COMPLEMENTARY DNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTEIN S 16; RIBOSOMAL PROTEIN L6; RIBOSOME PROTEIN;

ADULT; AGED; ARTICLE; BIOSYNTHESIS; DNA MICROARRAY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMAGE PROCESSING; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; UPREGULATION;

ACTINS; ADULT; AGED; CARCINOMA, HEPATOCELLULAR; DNA, COMPLEMENTARY; DOWN-REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; LIVER; LIVER NEOPLASMS; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RIBOSOMAL PROTEINS; UP-REGULATION;

EID: 0033648033     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: 10.3727/096504001108747530     Document Type: Article

References (69)

1. Parkin, D. M.; Pisani, P.; Ferlay, J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int. J. Cancer 80:827-841; 1999.
2. Ferlay, J.; Parkin, D. M.; Pisani, P. GLOBOCAN: Cancer incidence and mortality worldwide. International Agency for Research on Cancer (IARC) Cancer Base 3, IARC, Lyon, France; 1998.
3. Yu, M. W.; Chen, C. J. Hepatitis B and C viruses in the development of hepatocellular carcinoma. Crit. Rev. Oncol. Hematol. 17: 71-91; 1994.
4. Yu, M. W.; You, S. L.; Chang, A. S.; Lu, S. N.; Liaw, Y. F.; Chen, C. J. Association between hepatitis C virus antibodies and hepalocellular carcinoma in Taiwan. Cancer Res. 51:5621-5625; 1991.
5. Chang, C. C.; Yu, M. W.; Lu, C. F.; Yang, C. S.; Chen, C. J. A nested case-control study on association between hepatitis C virus antibodies and primary liver cancer in a cohort of 9,775 men in Taiwan. J. Med. Virol. 43:276-280; 1994.
6. Kolars, J. C. Aflatoxin and hepatocellular carcinoma: A useful paradigm for environmentally induced carcinogenesis. Hepatology 16:848-851; 1992.
7. Tanaka, K.; Hirohata, T.; Takeshita, S.; Hirohata, I.; Koga, S.; Sugimachi, K.; Kanematsu, T.; Ohryohji, F.; Ishibashi, H. Hepatitis B virus, cigarette smoking and alcohol consumption in the development of hepatocellular carcinoma: A case-control study in Fukuoka, Japan. Int. J. Cancer 51:509-514; 1992.
8. Austin, H.; Delzell, E.; Grufferman, S.; Levine, R.; Morrison, A. S.; Stolley, P. D.; Cole, P. A case-control study of hepatocellular carcinoma and the hepatitis B virus, cigarette smoking, and alcohol consumption. Cancer Res. 46:962-966; 1986.
9. Chen, C. J.; Liang, K. Y.; Chang, A. S.; Chang, Y. C.; Lu, S. N.; Liaw, Y. F.; Chang, W. Y.; Sheen, M. C.; Lin, T. M. Effects of hepatitis B virus, alcohol drinking, cigarette smoking and familial tendency on hepalocellular carcinoma. Hepatology 13:398-406; 1991.
10. Sager, R. Tumor suppressor genes: The puzzle and the promise. Science 246:1406-1412; 1989.
11. Hsu, H. C.; Wu, T. T.; Wu, M. Z.; Sheu, J. C.; Lee, C. S.; Chen, D. S. Tumor invasiveness and prognosis in resected hepatocellular carcinoma. Clinical and pathogenetic implications. Cancer 61: 2095-2099; 1988.
12. Liang, P.; Averboukh, L.; Keyomarsi, K.; Sager, R.; Pardee, A. B. Differential display and cloning of messenger RNAs from human breast cancer versus mammary epithelial cells. Cancer Res. 52:6966-6968; 1992.
13. Liang, P.; Pardee, A. B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257: 967-971; 1992.
14. Sager, R. Expression genetics in cancer: Shifting the focus from DNA to RNA. Proc. Natl. Acad. Sci. USA 94:952-955; 1997.
15. Zhang, J. S.; Duncan, E. L.; Chang, A. C.; Reddel, R. R. Differential display of mRNA. Mol. Biotechnol. 10:155-165; 1998.
16. Sun, Y.; Hegamyer, G.; Colburn, N. H. Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: One is homologous to human tissue inhibitor of metalloproteinases-3. Cancer Res. 54:1139-1144; 1994.
17. Sunaga, M.; Yoshikawa, M.; Ebara, M.; Kondo, F.; Kashiwada, M.; Takemori, T.; Saisho, H. Expression of cellular adhesion regulatory molecule in hepatocellular carcinoma. J. Gastroenterol. Hepatol. 13:878-884; 1998.
18. Sun, L.; Hui, A. M.; Kanai, Y.; Sakamoto, M.; Hirohashi, S. Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogencsis. Jpn. J. Cancer Res. 88:1165-1170; 1997.
19. Barnard, G. F.; Staniunas, R. J.; Mori, M.; Puder, M.; Jessup, M. J.; Steele, G. D. J.; Chen, L. B. Gastric and hepatocellular carcinomas do not overexpress the same ribosomal protein messenger RNAs as colonie carcinoma. Cancer Res. 53:4048-4052; 1993.
20. Begum, N. A.; Mori, M.; Matsumata, T.; Takenaka, K.; Sugimachi, K.; Barnard, G. F. Differential display and integrin alpha 6 messenger RNA overexpression in hepatocellular carcinoma. Hepatology 22:1447-1455; 1995.
21. Hsu, H. C.; Cheng, W.; Lai, P. L. Cloning and expression of a developmentally regulated transcript MXR7 in hepatocellular carcinoma: Biological significance and temporospatial distribution. Cancer Res. 57:5179-5184; 1997.
22. Edwards, D. R.; Denhardt, D. T. A study of mitochondrial and nuclear transcription with cloned cDNA probes. Changes in the relative abundance of mitochondrial transcripts after stimulation of quiescent mouse fibroblasts. Exp. Cell Res. 157:127-143; 1985.
23. Tso, J. Y.; Sun, X. H.; Kao, T. H.; Reece, K. S.; Wu, R. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 13:2485-2502; 1985.
24. Warburg, O. On the origin of cancer cells. Science 123:309-314; 1956.
25. Gong, Y.; Cui, L.; Minuk, G. Y. Comparison of glyceraldehyde-3-phosphate dehydrogenase and 28s-ribosomal RNA gene expression in human hepatocellular carcinoma. Hepatology 23:734-737; 1996.
26. Tokunaga, K.; Nakamura, Y.; Sakata, K.; Fujimori, K.; Ohkubo, M.; Sawada, K.; Sakiyama, S. Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res. 47:5616-5619; 1987.
27. Schek, N.; Hall, B. L.; Finn, O. J. Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma. Cancer Res. 48:6354-6359; 1988.
28. Arcari, P.; Martinelli, R.; Salvatore, F. The complete sequence of a full length cDNA for human liver glyceraldenyde-3-phosphate dehydrogenase: Evidence for multiple mRNA species. Nucleic Acids Res. 12:9179-9189; 1984.
29. Pogue-Geile, K.; Geiser, J. R.; Shu, M.; Miller, C.; Wool, I. G.; Meisler, A. I.; Pipas; J. M. Ribosomal protein genes are overexpressed in colorectal cancer: Isolation of a cDNA clone encoding the human S3 ribosomal protein. Mol. Cell. Biol. 11:3842-3849; 1991.
30. Barnard, G. F.; Staniunas, R. J.; Bao, S.; Mafune, K.; Steele, G. D. J.; Gollan, J. L.; Chen, L. B. Increased expression of human ribosomal phosphoprotein P0 messenger RNA in hepatocellular carcinoma and colon carcinoma. Cancer Res. 52:3067-3072; 1992.
31. Wolf, C. R.; Mahmood, A.; Henderson, C. J.; McLeod, R.; Manson, M. M.; Neal, G. E.; Hayes; J. D. Modulation of the cytochrome P450 system as a mechanism of chemoprotection. IARC Scientific Publications (Lyon) 165-173; 1996.
32. Lieber, C. S. Hepatic, metabolic and toxic effects of ethanol: 1991 update. Alcohol. Clin. Exp. Res. 15:573-592; 1991.
33. Tsutsumi, M.; Lasker, J. M.; Shimizu, M.; Rosman, A. S.; Lieber, C. S. The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver. Hepatology 10:437-446; 1989.
34. Lieber, C. S. Biochemical and molecular basis of alcohol-induced injury to liver and other tissues. N. Engl. J. Med. 319:1639-1650; 1988.
35. Koop, D. R. Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB J. 6:724-730; 1992.
36. Mukaiya, M.; Nishi, M.; Miyake, U.; Hirata, K. Chronic liver diseases for the risk of hepatocellular carcinoma: A case-control study in Japan. Etiologic association of alcohol consumption, cigarette smoking and the development of chronic liver diseases. Hepatogastroenterology 45:2328-2332; 1998.
37. Donato, F.; Tagger, A.; Chiesa, R.; Ribero, M. L.; Tomasoni, V.; Fasola, M.; Gelatti; Portera, G.; Boffetta, P.; Nardi, G. Hepatitis B and C virus infection, alcohol drinking, and hepatocellular carcinoma: A case-control study in Italy. Brescia HCC Study. Hepatology 26:579-584; 1997.
38. Matsuhashi, T.; Yamada, N.; Shinzawa, H.; Takahashi, T. Effect of alcohol on tumor growth of hepatocellular carcinoma with type C cirrhosis. Intern. Med. 35:443-448; 1996.
39. McCoy, G. D.; Hecht, S. S.; Wynder, E. L. The roles of tobacco, alcohol, and diet in the etiology of upper alimentary and respiratory tract cancers. Prev. Med. 9:622-629; 1980.
40. Cherian, M. G. Metallothionein and its interaction with metals. In: Goyer, R. A.; Cherian, M. G., eds. Toxicology of metals biochemical aspects. Berlin/Heidelberg: Springer-Verlag Inc.; 1995:121-132.
41. Andrews, G. K.; Adamson, E. D.; Gedamu, L. The ontogeny of expression of murine metallothionein: Comparison with the alpha-fetoprotein gene. Dev. Biol. 103:294-303; 1984.
42. Fresno, M.; Wu, W.; Rodriguez, J. M.; Nadji, M. Localization of metallothionein in breast carcinomas. An immunohistochcmical study. Virchows Arch. A Pathol. Anat. Histopathol. 423:215-219; 1993.
43. Giuffre, G.; Barresi, G.; Stumiolo, G. C.; Sarnelli, R.; D'I; Tuccari, G. Immunohistochemical expression of metallothionein in normal human colorectal mucosa, in adenomas and in adenocarcinomas and their associated metastases. Histopathology 29: 347-354; 1996.
44. Goulding, H.; Jasani, B.; Pereira, H.; Reid, A.; Galca, M.; Bell, J. A.; Elston, C. W.; Robertson, J. F.; Blarney, R. W.; Nicholson, R. A. Metallothionein expression in human breast cancer. Br. J. Cancer 72:968-972; 1995.
45. Ohshio, G.; Imamura, T.; Okada, N.; Wang, Z. H.; Yamaki, K.; Kyogoku, T.; Suwa, H.; Yamabe, H.; Imamura, M. Immunohistochemical study of metallothionein in pancreatic carcinomas. J. Cancer Res. Clin. Oncol. 122:351-355; 1996.
46. Chin, J. L.; Banerjee, D.; Kadhim, S. A.; Kontozoglou, T. E.; Chauvin, P. J.; Cherian, M. G. Metallothionein in testicular germ cell tumors and drug resistance. Clinical correlation. Cancer 72: 3029-3035; 1993.
47. Zeiger, B.; Hittmair, A.; Schir, M.; Ofner, C.; Ofner, D.; Fritsch, P. O.; Bocker, W.; Jasani, B.; Schmid, K. W. Immunohistochemically demonstrated metallothionein expression in malignant melanoma. Histopathology 23:257-263; 1993.
48. Bahnson, R. R.; Banner, B. F.; Ernstoff, M. S.; Lazo, J. S.; Cherian, M. G.; Banerjee, D.; Chin, J. L. Immunohistochemical localization of metallothionein in transitional cell carcinoma of the bladder. J. Urol. 146:1518-1520; 1991.
49. Deng, D. X.; Chakrabarti, S.; Waalkes, M. P.; Cherian, M. G. Metallothionein and apoptosis in primary human hepatocellular carcinoma and metastatic adenocarcinoma. Histopathology 32: 340-347; 1998.
50. Onosaka, S.; Min, K. S.; Fukuhara, C.; Tanaka, K.; Tashiro, S.; Shimizu, I.; Furuta M.; Yasutomi, T.; Kobashi, K.; Yamamoto, K. Concentrations of metallothionein and metals in malignant and non-malignant tissues in human liver. Toxicology 38:261-268; 1986.
51. Cherian, M. G. The significance of the nuclear and cytoplasmic localization of metallothionein in human liver and tumor cells. Env. Health Perspect. 102(Suppl.)3:131-135; 1994.
52. Blostein R. E.; Rutter, W. J. Comparative studies of liver and muscle aldolase. J. Biol. Chem. 238:3280-3285; 1963.
53. Rutter, W. J. Evolution of aldolase. Fed. Proc. 23:1248-1257; 1964.
54. Penhoet, E. E.; Kochman, M.; Rutter, W. J. Isolation of fructose diphosphate aldolases A, B, and C. Biochemistry 8:4391-4395; 1969.
55. 31P magnetic resonance spectroscopy. Lancet 2:931-934; 1987.
56. Asaka, M.; Kimura, T.; Meguro, T.; Kato, M.; Kudo, M.; Miyazaki, T.; Alpert, E. Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases. J. Clin. Lab. Anal. 8:144-148; 1994.
57. Asaka, M.; Kimura, T.; Nishikawa, S.; Miyazuki, T.; Alpert, E. Decreased serum aldolase B levels in patients with malignant tumors. Cancer 62:2554-2557; 1988.
58. Royds, J. A.; Kennedy, H. J.; Little, P. V.; Taylor, C. B.; Triger, D. R. Serum aldolase isoenzymes in benign and malignant liver disease. Clin. Chim. Acta 167:237-246; 1987.
59. Asaka, M.; Miyazaki, T.; Hollinger, F. B.; Alpert, E. Human aldolase B serum levels: A marker of liver injury. Hepatology 4:531-535; 1984.
60. Amemiya, N.; Yatomi, Y.; Endo, T.; Mizoc, A.; Yoda-Endo, M.; Yuminamochi, T.; Yamamoto, M.; Matsumoto, Y.; Ozaki, Y.; Kume, S. A case of hepatocellular carcinoma with marked hyperfibrinogenemia. Acta Haematol. 97:236-238; 1997.
61. Ansari, A.; Silvis, S. E. Plasma fibrinogen in health and disease. Its application in the differential diagnosis of an enlarged and irregular liver. Am. J. Gastroenterol. 57:13-19; 1972.
62. Brugarolas, A.; Elias, E. G. Incidence of hyperfibrinogenemia in 1961 patients with cancer. J. Surg. Oncol. 5:359-364; 1973.
63. Callea, F.; Favret, M.; Marino, C.; Brisigotti, M. Pathology of hepatocellular carcinoma. J. Surg. Oncol. Suppl. 3:168-169; 1993.
64. Callea, F. Natural history of hepatocellular carcinoma as viewed by the pathologist. Appl. Pathol. 6:105-116; 1988.
65. Hiramatsu, S.; Kojima, J.; Okada, T. T.; Inai, S.; Ohmori, K. The serum protein profile in chronic hepatitis, cirrhosis and liver cancer. Acta Hepatogastroenterol. 23:177-182; 1976.
66. Murray-Lyon, I. M.; Clarke, H. G.; McPherson, K.; Williams, R. Quantitative immunoelectrophoresis of serum proteins in cryptogenic cirrhosis, alcoholic cirrhosis and active chronic hepatitis. Clin. Chim. Acta 39:215-220; 1972.
67. Housley, J. Alpha-2-macroglobulin levels in disease in man. J. Clin. Pathol. 21:27-31; 1968.
68. Cleve, H.; Strohmeyer, G. Quantitative variations of serum glycoproteins in pathological processes; determination of acid alpha-I-glycoprotein, Gc and alpha-2-macroglobulin using radial immunodiffusion. Klin. Wochenschr. 45:1051-1054; 1967.
69. Kramer, R. Structural and functional aspects of the phosphate carrier from mitochondria. Kidney Int. 49:947-952; 1996.