Human polyomavirus BK (BKV) and neuroblastoma: Mechanisms of oncogenic action and possible strategy for novel treatment

Medical and Pediatric Oncology

Volumn 35, Issue 6, 2000, Pages 593-596

  Jorgensen G E K ^a   Johnsen, J I ^a   Ponthan, F ^b   Kogner, P ^b   Flgstad, T ^a   Traavik, T ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; PROTEIN P21; PROTEIN P53; VIRUS LARGE T ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; APOPTOSIS; CONFERENCE PAPER; CONTROLLED STUDY; DNA SEQUENCE; HUMAN; HUMAN CELL; NEUROBLASTOMA; NONHUMAN; POLYOMA VIRUS; PRIORITY JOURNAL; RAT; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT; VIRUS CARCINOGENESIS;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; GENES, P53; HUMANS; NEUROBLASTOMA; RATS; TUMOR CELLS, CULTURED;

EID: 0033647385     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-911X(20001201)35:6<593::AID-MPO22>3.0.CO;2-I     Document Type: Conference Paper

References (16)

1. Wildtype p53 undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
2. The p53 signal-transduction pathway is intact in human neuroblastoma despite cytoplasmic localization
3. A possible contributory role of BK virus infection in neuroblastoma developments
4. Transformation by polyomaviruses: Role of tumor suppressor proteins
5. Definition of a continuous human cell line derived from neuroblastoma
6. Cytoplasmic sequestration of wild-type p53 impairs the G1 checkpoint after DNA damage
7. The polyproline region of p53 is required to activate apoptosis but not growth arrest
8. The p53 gene in breast cancer: Prognostic value of complementary DNA sequencing versus immunohistochemistry
9. A two-fusion partner system for raising antibodies against small immunogens expressed in bacteria
10. Amplification and sequencing of the control regions of BK and JC virus from human urine by polymerase chain reaction
11. Protein synthesis-dependent cytoplasmic translocation of p53 protein after serum stimulation of growth-arrested MCF-7 cells
12. Biochemical properties and biological effects of p53
13. Expression of viral T-antigen in pathological tissues from transgenic mice carrying JC-SV40 chimeric DNAs
14. Metastasizing neuroblastomas in mice transgenic for simian virus 40 large T (SV40T) under the olfactory marker protein gene promoter
15. Association of BK and JC human polyomaviruses and SV40 with human tumors